Gene variant increases risk for alcoholism following childhood abuse
... childhood sexual abuse are more likely to develop alcoholism later in life if they possess a particular variant...influences the impact of childhood sexual abuse on alcoholism and antisocial personality disorder (ASPD) in women, says Dr. Ducci. She and her colleagues analyz...Spousal choices can influence the risk of developing alcoholism
...s drinking behavior. "Phenotypic assortment for alcoholism risk is part of a much larger phenomenon, having deep evolutionary roots," commented Michael Vanyukov, associate professor of pharmaceutical sciences, psychiatry and human genetics at the University of Pittsburgh. "Selecting a phenotypically similar...Study advances evidence for receptor's role in alcohol pleasure and problems
... of General Psychiatry. "Although the pathway to alcoholism is influenced by many factors, our findings affirm that individuals who possess this receptor variant may experience enhanced pleasurable effects from alcohol that could increase their risk for developing alcohol abuse and dependence," notes Markus H...A form of the alcohol dehydrogenase gene may protect Afro-Trinidadians from developing alcoholism
...e less likely to have a positive family history of alcoholism both of which are associated with a reduced vulne...e provides some genetic protection from developing alcoholism but it is not complete. Individuals can choose to drink at high levels in spite of having some prot...The glutamate decarboxylase 1 gene may play a pivotal role in developing alcoholism
...he GAD1 gene may play a role in the development of alcoholism as well as the outcome of alcohol withdrawal. Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the brain. GABA has been implicated in the development of alcoholism, although the mechanisms through which this occurs are un...Animals resistant to drunken behavior offer clues to alcoholism's roots
...of ethanol is a risk factor for the development of alcoholism and is genetically determined, at least in part. Thus, the researchers said, an understanding of the molecular mechanisms underlying ethanol resistance might provide important clues about alcohol addiction. The Italian researchers, who normally stu...Study links receptor to stress-induced alcohol relapse
...eriods of sobriety is a defining characteristic of alcoholism and is often triggered by stress. A new study in rats reports that a specific receptor for a stress-response transmitter may play an important role in stress-induced relapse. The study, a collaboration between scientists at the National Institute o...Study offers clues to brain's protective mechanisms against alcoholism
...Why do some people with a strong family history of alcoholism develop alcohol dependency while others do not? A ...pamine D2 receptors may provide protection against alcoholism by triggering the brain circuits involved in inhibiting behavioral responses to the presence of alco...Gene-on-gene interactions may influence risk for developing alcoholism
...t, "and that may decrease some people's risk for alcoholism slightly." Schuckit said that these findings wil...ho think it's hard to see behavioral problems like alcoholism being impacted by genes, but of course it is, because genes affect what you were like before you t...NIH unprecedented genetic study may help identify people most at risk for alcoholism
... diseases." "Previous studies established that alcoholism runs in families, but this research has given us t...portant contribution to studies of the genetics of alcoholism and co-occurring substance use disorders," adds Dr. Ting-Kai Li, director of the National Institute ...A new tool against brain disease
...ing cigarettes, and the same method might work for alcoholism because nicotinic receptors may be involved in alcohol addiction, McIntosh says. Other nicotinic receptors trigger the release of neurotransmitters involved in memory, so activating the right receptors might lessen Alzheimer's memory loss. "One...The more alcoholic relatives a person has, the more they need to drink to feel alcohol's effects
... an important component of how a family history of alcoholism conveys a person's greater risk of developing alcoholism him or herself. New findings indicate that the more alcoholic relatives a person has, the lower thei...Personality and parents' alcoholism interact to influence a person's risk of becoming an alcoholic
Personality and parental alcoholism interact to influence an individual's risk of beco...nality trait called "novelty seeking" and parental alcoholism can both increase risk of, and protect against, developing individual alcoholism. High novelty see...Both alcoholism and chronic smoking can damage the brain's prefrontal cortex
...socorticolimbic system. New findings indicate that alcoholism and chronic smoking have a higher number of common...paminergic neurons. While the long-term effect of alcoholism on the human brain has been investigated, surprisingly little is known about the long-term effect of...Analysis highlights areas for research into genetic causes of alcoholism
...er understanding of alcoholism. Genetic studies of alcoholism have long confirmed the complexity of the disease and uncovering the underlying molecular mechanisms remains a formidable task. The meta-analysis was completed by Susan Bergeson, an assistant professor of neurobiology at The University of Texas at A...Researchers seek answers to combat TB epidemic
...cine. The researchers hope to pinpoint the role of alcoholism in the global epidemic by studying a population of HIV- and tuberculosis-infected patients in India. The researchers are collecting data for the National Institutes of Health-funded project and hope to have answers within two to three years, Antony s...Same genes may underlie alcohol and nicotine co-abuse
... smoking is three times more common in people with alcoholism than in the general population. Since previous studies have also determined that genetics plays an important role in both alcohol and nicotine addictions, researchers have hypothesized that the same gene or genes may influence the co-abuse of these ...Smoking interferes with brain's recovery from alcoholism
... are, says Meyerhoff, then professionals who treat alcoholism may wish to consider adding smoking cessation to their usual treatment plans. "This may be a lot to ask from an alcoholic individual going through drastic brain chemical imbalances in early recovery," he acknowledges. "But it may lead to faster brain...Genetic and environmental influences on alcohol consumption among rhesus monkeys
...ighly social, which is important for diseases like alcoholism where there are social factors affecting alcohol consumption. And, finally, because we can control their social environment and precisely measure their exposure to alcohol, whereas human studies often rely on self-reported consumption patterns." Re...Alcoholism, smoking and genetics among Plains American Indians
...on. Yet little is known about the co-morbidity of alcoholism and smoking among American Indians. In the March ... that the Met allele is associated with late onset alcoholism and increased alcohol intake in social drinkers, Enoch and her colleagues have found that in America...