Tag: "alleles" at biology news
Competition, loss of selfishness mark shift to supersociety
... societies that are less organized. Thus, genes or alleles
that code for such behaviors will be propagated faster, Hlldobler says. The second piece of the model takes into account that as the colonial organization of one group rises, there is a coincident rise in discrimination against members of other soc...
Dietary preferences and patterns may be linked to genes
...ls expression, or behavior, of the APOA2 gene. The alleles
of the APOA2 promoter, T and C, form combinations;...esearchers did not find an association between any alleles
of APOA2 and blood lipid levels, including triglycerides, total cholesterol, or LDL or HDL cholester...
Nobel laureate James Watson receives personal genome in ceremony at Baylor College of Medicine
... disease. They also looked for gene variants or alleles
that can raise the risk of chronic diseases such as those of the heart or kidneys. The HGSC also managed the process of providing the information to Watson, which included designing an ethical model for providing the data, writing a consent form t...
Landmark study highlights complex genetic risk factors behind type 2 diabetes
...thors of the paper. "Clearly, the more 'high risk' alleles
a person inherits, the higher the likelihood that they will go on to develop diabetes." The exact role of the genes that have been implicated by these studies is still uncertain. However, two of them appear to be involved in the development, functi...
Genes and stressed-out parents lead to shy kids
...onsistently shy behavior. "If you have two short alleles
of this serotonin gene, but your mom is not stressed, you will be no more shy than your peers as a school age child," says Fox. "But we found that when stress enters the picture, the gene starts to show a strong relationship to the child's behavior,"...
A form of the alcohol dehydrogenase gene may protect Afro-Trinidadians from developing alcoholism
...at two loci, ADH1B and ADH1C . While the three alleles
at the ADH1B locus have previously been linked with protection from alcohol dependence, a new study is the first to examine the relationship between the ADH1B*3 allele and alcohol-related disorders among Afro-Trinidadians. Findings indicate that...
Screening for complex genetic interactions
...teraction is defined by heterozygous null/wildtype alleles
in two different genes that combine to yield a more severe phenotypic defect. To illustrate the utility of this novel approach, the researchers culled through nearly 5000 strains of yeast to identify over 200 genes that interact with actin. This pape...
Genetic study of Neanderthal DNA reveals early split between humans and Neanderthals
... our data as an abundance of low-frequency derived alleles
in Europeans where the derived allele matches Neanderthal. No site in the data set appears to be of this type." However, Pritchard said, "We do not exclude the possibility of modest levels of genome admixture." Pritchard's team suggests that human ...
Your genes may hold key to how sick you get from the flu
...rm goal is to identify genomic regions, genes, and alleles
that control variation in inflammation during infection with influenza virus, Trammell said. The identification of these genomic regions has enormous implications for understanding and avoiding the fatality associated with infection. These studies ar...
Insights into honey bee sex gene could bring sweet success in breeding
... die out. "If we know more details about how many alleles
there are and what their frequencies are, bee bree... this effort by providing a direct tool to examine alleles
from different populations." In the research, Zhang and coworkers from U-M, Michigan State Universi...
Affymetrix 500K array used to identify memory gene
...olecular level. The study entitled, "Common KIBRA alleles
are associated with human memory performance," will be published in the Oct. 20, 2006 issue of Science. The research team was led by Dietrich Stephan, Ph.D., director of TGen's Neurogenomics Division. It included colleagues at the University of Zuric...
Early family experience can reverse the effects of genes, UCLA psychologists report
...rticipants' standing on the 5-HTTLPR had two short alleles
(s/s), a short and a long allele (s/l) or two long alleles
(l/l) for the serotonin transporter gene. (An allele is any of several forms of a gene.) The rese...
When two mutants collide: How XPD disorders can be partially rescued in compound heterozygotes
...ndrome (CS), all of which involve different mutant alleles
in the XPD gene, two copies of the individual muta... However, understanding how these different mutant alleles
interact with one another is difficult in humans due to our inability to distinguish environmental a...
Variation in 3 genes influences risk of age-related macular degeneration
.... They observed additive accumulation of risk from alleles
at these three genes, including CFH on chromosome 1, complement factor B (BF) and complement component 2 (C2) genes on chromosome 6, and the LOC gene on chromosome 10. They estimate that genotypes related to five variants in these three genes explai...
Major genetic risk factor found for prostate cancer
...eedman et al. report that the previously described alleles
only explain a fraction of the admixture signal; therefore 8q24 still contains a major unidentified risk gene for prostate cancer. ...
Metal homeostasis research in plants will lead to nutrient-rich food and higher yielding crops
...ion in yeast, Guerinot and her colleagues isolated alleles
of IRT1 that no longer facilitate the accumulation...ility to transport Iron. When the engineered IRT1 alleles
are expressed in plants that no longer express a wild type copy of IRT1, the engineered allele allow...
Researcher gives hard thoughts on soft inheritance
...chards cites a study that shows certain epigenetic alleles
can be inherited that affect tumor suppressor genes. His own work in plants has often shown epigenetic information can be inherited. The Richards lab specializes in epigenetics, a biological field that deals with information stored "above and beyond ...
Pathway toward gene silencing described in plants
...me genes are selectively silenced and how silenced alleles
can be turned on again may someday have practical benefits. For instance, tumor suppressor genes that normally help keep cells from dividing uncontrollably are often silenced by DNA methylation and histone (proteins that wrap DNA) modifications in c...
Rhesus monkeys in Nepal may provide new alternative for HIV/AIDS research
...osomes. They also looked for the presence of other alleles
that are known to influence immunity and the rate of disease progression in the animals, including one that is present in Indian rhesus macaques but not in the Chinese ones. Kyes, who also is a UW research associate professor of psychology, said th...
Gladstone scientists prove neurons produce Alzheimer's-linked apolipoprotein E
...d his team have succeeded in making one of the two alleles
of the apoE gene produce a green fluorescent protein that represents apoE, while the remaining allele functions normally. Thus, under a microscope, the bright green fluorescence, dubbed EGFPapoE, shows researchers wherever the apoE gene is expressed....
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