Brain networks strengthened by closing ion channels
...nsten said inhibiting cAMP closes the channels and allows the network to reconnect. The study also found alpha-2A adrenergic receptors near the channels that inhibit the production of cAMP and allow the information to pass through into the cell, connecting the network. These receptors are stimulated by a na...News tips from the Journal of Biological Chemistry
...ns through the opening that activate the egg. This allows the sperm cell to further enter the egg and mix it...re silenced. This process, called gene repression, allows cells to perform specialized tasks that are different among various organs. Previous studies have sh...OHSU lab finds meth receptor that could lead to therapy
...Biology at OHSU is one of the few in the U.S. that allows biologists and chemists to work side-by-side, using their combined skills to identify drug targets and to design new drugs to treat diseases like drug addiction," said David Dawson, Ph.D., OHSU professor and chairman of physiology and pharmacology. "...New imaging approach promises insights into multiple sclerosis
...eath, Cheng said. "Combining these three methods allows us to conduct more specific and precise molecular analyses," he said. "Ultimately, this work paves the way toward studying the degradation of the myelin sheath as a result of multiple sclerosis and analyzing living tissue to study the mechanisms of ...Researchers develop technique for bacteria crowd control
...ditional centrifuging techniques, the new approach allows selective concentration of healthy cells," said Andrey Sokolov, Ph.D. student from Illinois Institute of Technology and contributor to the research. In addition to the development of the device used in the experimentation, research findings uncove...Bioluminescence at the service of a novel cerebral imaging technique
...rmore, this little-invasive and non-toxic approach allows the recording of neuronal activity over periods of several hours. It is thus possible to monitor the cerebral activity of a Drosophila fruit fly for 24 or even 48 hours. Because of these characteristics, the new tracer can demonstrate new physiol...New diagnostic technologies offer non-invasive means
...eter long. The nature of the individual components allows the researchers to modify the size of the holes in the lattice to form sponge-like pores small enough to catch a single protein biomarker. To entice biomarkers into the pores, Luchini and her colleagues are using "bait" that is specific for either ...Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex
... highly sensitive mass spectrometry methods. "This allows you to get the chance to say, Wait, they really are related because their sequences are related. We didnt get enough sequences to definitively say that, but what sequences we got support that idea." In another study appearing in the same issue of S...Ancient T. rex and mastodon protein fragments discovered, sequenced
...itecture' of the bones," Asara said. "This finding allows us the ability to say that they really are related because their sequences are related." "Scientists had long assumed that the material in fossil bones would not be preserved after millions of years of burial," said Enriqueta Barrera, program direc...Third primate genome, the rhesus macaque, helps illuminate what makes us human
...que Genome Sequencing and Analysis Consortium. "It allows us to learn what has been added or deleted in primate evolution from the rhesus macaque to the chimpanzee to the human." The Rhesus Macaque Genome Sequencing and Analysis Consortium, an international team of more than 170 scientists from 35 institu...Massive gene screening points way to more effective chemotherapy
...gs were made possible because of a technology that allows scientists to rapidly test how cells react when a given gene is turned off, or "silenced." The so-called high-throughput employs a series of small plastic dishes, each with 96 wells. Using a robot, researchers place small bits of RNA that can block t...World's top engineers in San Antonio for system of systems conference
...ustries have already embraced the technology which allows the integration of independent operational systems to create large "super systems" to complete a task. "We will also announce a new national consortium that will bring military, industry and academia together to network to pursue large governmental...Little lifesavers -- Nanoparticles improve delivery of medicines and diagnostics
...e new technique, dubbed "Flash NanoPrecipitation," allows the researchers to mix drugs and materials that encapsulate them. Similar mixing techniques previously have been used to create bulkier pharmaceutical products and have proven practical on a commercial scale. The Princeton-led team, which includes ch...Structural basis for photoswitching in fluorescent proteins brought into focus
...w these molecules can be switched on and off. That allows us to design new variants to make the proteins more useful." For more than a decade, fluorescent proteins first isolated in jellyfish and since found in a variety of colors from coral reef organisms revolutionized molecular biology, allowing scie...New study sheds light on long-term effects of logging after wildfire
...ould rather have the long-term data, using a model allows us to estimate some of the future ecological effects." The computer simulation showed that the difference in surface fuels between logged and unlogged units would persist for about 15 years. The simulation also showed that if a fire did start duri...MIT model helps researchers 'see' brain development
...he folds of the brain mathematically in a way that allows the researchers to analyze their changes over time and space. The original brain scan is then represented computationally with points. Charting each baby's brain requires about 130,000 points per hemisphere. Yu decomposed these points into a repre......e precursor and muscle cells. Cre is a switch that allows us to turn the fusion gene on and off when and where we want it, says Capecchi. In less mature muscle cell precursors, the SYT-SSX2 gene disrupted normal development of mouse embryos, and they died, but there was no cancer. When the cancer gene...Researchers identify gene involved in dog size
...twork. The availability of the dog genome sequence allows researchers to better compare the human and dog genomes and narrow their search for genetic contributors to cancer and other major diseases. Researchers can access the dog sequence data through the following public databases: Dog Genome Resources (...Better together: Bacterial endosymbionts are essential for the reproduction of a fungus
...ore formation in fungi is a universal process that allows the rapid distribution of fungal cells. The new findings appear to represent the first known case in which spore formationalso known as vegetative reproductiondepends on the presence of another organism. The researchers found that when both organis...