Inflammation may cause preterm labor and fetal deaths
...ucleatum, a common oral pathogen also found in the amniotic fluid of preterm babies, was used as the model organism for the study. Around day 16 of the gestation period for the mice (the equivalent of the third trimester for humans), F. nucleatum was injected into three groups of miceone that had TLR4 recept...A new method of adult stem cell growth efficacious in treatment of disorders of the cornea
...combines culture on a plastic chip with that of an amniotic membrane one. The novelty of the technique focuses...s are verified. The cells are transferred to the amniotic membrane growth culture, one that is highly suitable when dealing with stem cells that are to be tra...The opossum genome sequence casts light on evolution, immunity and disease
...the opossum genome, which is higher than any other amniotic lineage studied to date." Gentles and his colleagues also discovered ancient TEs that appear to have been recruited for specific biological activities. For example, they identified MER131, a non-protein coding sequence that is highly conserved in t...New proteomic method to detect inflammation in amniotic fluid
A score that measures the proteomic profile of amniotic fluid may predict inflammation before delivery. Re...t were closely associated with inflammation in the amniotic fluid, and developed a score based on these proteinsīthe "Mass Restricted" (MR) score. This score ha...American Chemical Society's Weekly PressPac -- December 6, 2006
...rkers for these hard-to-diagnose infections of the amniotic fluid, which surrounds the fetus prior to birth. ...d amniocentesis, in which a needle is used to take amniotic fluid through the abdominal wall. ARTICLE #1 FOR IMMEDIATE RELEASE "Proteomic Analysis of Cervic...Drug-induced labor increases risk of rare but serious delivery complication
...nd in the vessels surrounding the uterus, allowing amniotic fluid to escape into the mother's circulatory system. Though this complication is rare it can be serious and even fatal; amniotic-fluid embolism is one of the leading causes of maternal mortality in developed countries. Little is currently known abou...Children's Hospital Boston presents at the 2006 American Academy of Pediatrics National Conference
... birth defect, using stem cells extracted from the amniotic fluid before the baby is born. Using these cells, Shaun Kunisaki, MD and Dario Fauza, MD, at Children's Hospital Boston, have created a patch to close up a hole in the diaphragm, correcting a life-threatening condition known as congenital diaphragmat...Study shows prenatal diagnostic tests have low risk of miscarriage
...the abdominal wall and into the uterus to withdraw amniotic fluid. CVS is a biopsy procedure that involves removing a piece of tissue from the placenta. These samples are then cultured and chromosomes analyzed to determine abnormalities associated with Down syndrome and other genetic diseases such as cystic f...Genetic variant is associated with higher rate of premature delivery in African-American women
...ength to the membranes that surround the fetus and amniotic fluid. The genetic variant identified reduces the amount of Hsp47 made and thus the collagen in the membranes, making them more prone to rupture. Other published research has reported that reduced collagen content has been found in PPROM fetal memb...New procedure safer for detecting fetal anemia
...ses procedure, where a needle is inserted into the amniotic cavity under ultrasound guidance. This method is highly invasive and uncomfortable for the mother, and carries a risk of miscarriage of the pregnancy, as well as a risk of worsening the fetal anemia. " explains Dr. Seaward. "The Doppler ultrasonog...First link of oral bacteria and preterm birth found in human
... human between bacteria found in the mouth and the amniotic fluid of a woman in preterm labor. Using new DNA ...levels and elevated white blood cell counts in her amniotic fluid that she had an infection. An examination of the placenta, fetal lining and umbilical cord fo...Women's health findings presented at national conference
...valuate biomarkers employed to trace the action of amniotic fluid infection in an animal model. Tracer molecules attached to immune system cells, called macrophages, that are part of the body's inflammatory response, allowed the researchers to see evidence of inflammation in infected animals, all of which del...Preterm birth risk quickly and accurately detected with proteomic profiling
By profiling specific proteins in amniotic fluid for inflammation, researchers at Yale School...h is that the test was done using fresh samples of amniotic fluid and not using banked amniotic fluid. This is a multidisciplinary approach that combines the ba...Profiling amniotic fluid yields faster test for infection and preterm birth risk, researchers find
...today announced that profiling certain proteins in amniotic fluid is the fastest and most accurate way to dete...M member. "We found that profiling the proteins in amniotic fluid for markers of inflammation--a proteomic profile--not only yielded results twice as fast as ot...Cells from amniotic fluid used to tissue-engineer a new trachea
...dpipes) in fetal lambs, first using cells from the amniotic fluid to grow sections of cartilage tube, and then...n's that use the fetus's own cells, drawn from the amniotic fluid that surrounds it, to create patches to fix birth defects -- in this case, even before birth. ...Canadian-led study shows amnioinfusion does not reduce risk of meconium aspiration syndrome
...s when a newborn inhales a mixture of meconium and amniotic fluid during labor and delivery. Meconium is the ...tract during pregnancy and is formed from ingested amniotic fluid and dead intestinal cells. Although it is sterile, inhaled meconium is highly irritating to t...Discarded placentas deliver researchers promising cells similar to embryonic stem cells
...ta called the amnion, or the outer membrane of the amniotic sac, is comprised of cells that have strikingly si...g to the results of their studies, these so-called amniotic epithelial cells could in fact be directed to form liver, pancreas, heart and nerve cells under the ...Change in prenatal genetic testing could reduce detection rate of abnormalities
...hat provide prenatal diagnostic services submitted amniotic fluid and chorionic villus tissue** data from 1999... In total, the laboratories submitted over 119 500 amniotic fluid and 23 000 chorionic villus samples. The researchers analysed all abnormal karyotypes by reaso...Protein analysis of amniotic fluid reveals clues about preterm birth
...fying the presence of several distinct proteins in amniotic fluid. Study results will be published in the Marc...l of Medicine. The researchers tested the amniotic fluid for four distinct proteins they previously had linked to inflammation, a known cause of preter...Researchers find new technique to identify fetal genetic material from amniotic fluid
...enger RNA (ribonucleic acid) can be extracted from amniotic fluid (fluid around the fetus), and then be analyz... In addition, genetic analysis can be performed on amniotic fluid components " They add that the "cell-free component of the amniotic fluid is discarded after...