Tag: "amyotrophic" at biology news

Society for Psychophysiology Research

... with the outside world. The disease, also called amyotrophic lateral sclerosis, or ALS, slowly robs patients of all motor control while leaving their minds intact. Patients often end up "locked in" to their bodies, a nightmarish state in which they are unable to control so much as an eye blink and, until recen...

Gladstone researchers resolve key Huntington's disease mystery in Nature cover story

...ns, including Alzheimer's disease, prion diseases, amyotrophic lateral sclerosis (Lou Gehrig's disease), Parkinson's disease, and a group of nine so-called polyglutamine diseases of which Huntington's is the most widely known. Moreover, the approach could be used to measure the nature and magnitude of the relati...

Study using robotic microscope shows how mutant Huntington's protein affects neurons

... HD, Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis (ALS). The role of inclusion bodies in these diseases has long been controversial. Some studies suggest that they may be a critical part of the disease process, while others indicate that they may help protect the cells from toxic...

Dr. Harris receives NIH Javits Neuroscience Investigator Award

...es in 1983 to honor the late New York senator with amyotrophic lateral sclerosis who was an advocate for research of the brain and nervous system. Nearly 480 awards have been made to date. The award recognizes investigators who have made substantial contributions to the neurological science field and likely wi...

Leading scientists to discuss research applications for therapeutic cloning

...atments for disorders such as Parkinson's disease, amyotrophic lateral sclerosis (ALS), Alzheimer's disease, heart disease, stroke, diabetes, spinal cord injuries and genetic diseases. While the hopes are real, scientific findings remain ambiguous concerning actual benefits for patients using stem cells for ther...

University of South Florida designated Center of Excellence by Huntington's Disease Society

...s said. "Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis -- all involve the progressive loss of specific subsets of brain cells. At the molecular level, if we discover a therapy that works for Huntington's Disease it may also be applicable to these other central nervous system disorders."...

Efforts to clone primates move forward

... treating or curing diabetes, Parkinson's disease, amyotrophic lateral sclerosis (ALS), heart disease, stroke, spinal cord injury and genetic diseases. Scientists believe that embryonic stem cells may have the most versatility in potential cell-based treatments, but intensive research continues on both embryonic...

Human complexity and diversity spring from a surprisingly few (relatively speaking) genes

...been implicated in several human diseases, such as amyotrophic lateral sclerosis (Lou Gehrig's Disease), epilepsy and depression. Maas's group has analyzed brain tumor tissues and tissues from a healthy brain. "RNA editing, because of its effect on the ion channel, is very important for normal brain function," s...

Deciphering the genetic babel of brain cells

...cause their degeneration contributes critically to amyotrophic lateral sclerosis (Lou Gehrig's disease) and to the loss of muscle function in spinal cord injury. Better understanding of the genes that control the development of these neurons could aid in the development of treatments for these disorders. In thei...

Brain controls robot arm in monkey, University of Pittsburgh researcher reports at AAAS

... cord injuries or nervous system disorders such as amyotrophic lateral sclerosis or ALS," said Andrew Schwartz, Ph.D., professor of neurobiology at the University of Pittsburgh School of Medicine and senior researcher on the project. The neural prosthesis moves much like a natural arm, with a fully mobile should...

Scientists infuse rat spinal cords with brain-derived human stem cells

...urgeons treat the deadly neurodegenerative disease amyotrophic lateral sclerosis (ALS), researchers at the University of Wisconsin-Madison have inserted engineered human stem cells into the spinal cords of ALS-afflicted rats. Reporting their work today (April 19) in the journal Human Gene Therapy, the scientists...

New insight into Huntington's disease pathology

...." For example, they wrote, mouse model studies of amyotrophic lateral sclerosis, or Lou Gehrig's disease, had shown that pathological cell-cell interactions are critical to motor degeneration. "Thus, pathological cell-cell interactions may be a surprisingly common pathogenic mechanism warranting further studies...

Columbia University launches multi-year campaign to support stem cell research

...range of illnesses, including Parkinson's disease, amyotrophic lateral sclerosis (ALS), diabetes, pancreatic cancer, leukemia, stroke and other diseases of the nervous system, liver, eye, skin, and heart. Beyond replacement therapy, the use of stem cells as a research tool will lead to new insights regarding me...

Molecular trigger for Huntington's disease found

...ay a role in some forms of Parkinson's disease and amyotrophic lateral sclerosis, or Lou Gehrig's disease. Ironically, p53 is the same regulatory protein that is inactivated in a large fraction of cancers. This inactivation allows abnormal cancer cells to escape the cell's protective "suicide program" that would...

Sticky mutant proteins implicated in Lou Gehrig's disease

.... Over 5,600 people in the U.S. are diagnosed with amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease each year. About 30,000 Americans have the disease at any given time, and 10% of cases are inherited. "Amyotrophic lateral sclerosis is a neurodegenerative disorder in which neurons of the motor pathwa...

Breast cancer risk increased for African-Americans with mitochondrial DNA variant

...risk for Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis (Lou Gehrig's disease), and other neurological disorders. Canter and colleagues determined that the errant allele is associated with a significantly higher risk for breast cancer among African-American women who carry 10398A, but ha...

UCSF study points to link to neurodegenerative disease target

...ular neurodegenerative diseases in humans, such as amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, says study co-author Graeme Davis, PhD, associate professor and vice chair of the Department of Biochemistry and Biophysics at the University of California, San Francisco. "If we want to m...

Biomarker test may give early warning of brain woes

... in people who have had strokes or who suffer from amyotrophic lateral sclerosis, a debilitating disorder frequently referred to as ALS or Lou Gehrig's disease. Further studies will evaluate patients suffering from Alzheimer's disease and other serious damage and disease states of the nervous system. Drug resear...

Javits Award funds neurology of animal movement study

...ty of neurological disorders. Javits suffered from amyotrophic lateral sclerosis, the disabling neurodegenerative disorder also known as Lou Gehrig's disease. A component of the National Institutes of Health, the NINDS is the nation's primary federal sponsor of research on the brain and nervous system....

Protein aggregates in Lou Gehrig's disease linked to neuron death

...ch neurologist Jean-Martin Charcot first described amyotrophic lateral sclerosis (ALS) in 1869, but, nearly 140 years later, little is known about the cause of the devastating neurodegenerative disease, and there is no cure. What is known about Lou Gehrig's disease, as it is commonly called, is that misfolded ...

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(Date:10/14/2014)... the planet,s leading questions is how to produce enough ... climate. The Food and Agriculture Organization of the United ... the next 40 years to feed a growing global ... necessary rise in food production. Plants—grains, cereals, fruits, ... livestock. Current research must tap into our knowledge ...
(Date:10/14/2014)... CA – October 14, 2014 – Scientists from The ... from the National Institutes of Health (NIH) to lead ... virus-induced hemorrhagic fever disease in Africa. The study aims ... why some patients die, while others survive the inflection. ... understand the basic mechanism of how Lassa fever virus ...
(Date:10/14/2014)... likely takes between 10 and 20 years to ... window" of intervention if detected early, which may ... say Australian clinical researchers. , Dr Jeremy ... Institute of Medical Research, analysed medical histories and ... pancreatic cancer patients, operated on between 1994 and ...
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