Tag: "animal" at biology news
Doernbecher Children's Hospital scientist earns coveted Javits award
...osed work includes the use of a novel pre-clinical animal
model totest new translational strategies that wil...ry has been slow, Back says,because of the lack of animal
models to test therapies for the complexforms of brain injury that occur in human survivors of prema...
Gene regulation, not just genes, is what sets humans apart
...od into energy is essentially the same across most animal
species, the fine-tuning of how an organism deals with the different sorts of sugars and complex carbohydrates in its diet lies in the regulatory sequences, Wray said. Chimps are fruit-eaters, for the most part, and would not last long away from t...
Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
...ead investigator on the project. In addition, the animal
models developed in this study will open the door for future studies in which the effects of mitochondrial genome variation can be investigated on fixed nuclear genetic backgrounds. ...
Climate change and permafrost thaw alter greenhouse gas emissions in northern wetlands
... to the atmosphere, as previously frozen plant and animal
remains became susceptible to decay. This could serve as a positive feedback to climate change, where typically warming causes changes that release more greenhouse gases, which in turn causes more warming, and more emissions, and so on, she said. ...
OHSU turns mouse into factory for human liver cells
..., and the mouse liver, despite efforts to make the animal
immunodeficient, often rejected the human cells. Grompe's laboratory now has a system in which those disadvantages have been engineered out. It has created a severely immunodeficient mouse strain that develops liver disease only when the animals do...
Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
... and obesity. The results of their study, using an animal
model, suggest that estrogen depletion can have these effects. The study is entitled, "Role of Estrogens in Postmenopausal Obesity and Hypertension." It was conducted by Lourdes A. Fortepiani and Huimin Zhang, University of Texas Health Science C...
Testosterone replacement therapy: How safe for aging men?
...luated. A team of researchers has been using an animal
model to investigate potential links between testo...study and an overview of data from other human and animal
studies is part of the upcoming conference, Sex and Gender in Cardiovascular-Renal Physiology and Pa...
Female gender provides an advantage in renal diseases
...trogen in Renal Disease Previous studies using animal
models have used hormonal manipulation to explore the effects of sex hormones on renal disease. In these studies, researchers either added supplemental levels of estrogen/testosterone to rats or castrated/performed ovariectomies in males and females ...
Sugar and spice and everything nice: Health differences in newborn girls and boys
...lthy and when they are ill. Two studies using animal
models may lead to a better understanding of sex-based health discrepancies among some newborns. One study found that gender differences in the heart may help explain why infant girls are more likely to die following heart surgery. The other study ha...
Research aims to identify markers for menopausal women at risk for deadly blood clot
...e study builds on the teams earlier findings in an animal
model. They are applying the earlier results to a human population for the first time using blood taken from the women enrolled in the KEEPS trial. Depending upon the results from this group, a larger trial of 720 samples will be examined. Dependi...
The 'female advantage' in kidney disease does not extend to diabetic women
...estrogen-like supplements protect the kidney in an animal
model of diabetic renal disease, suggesting that restoring estrogen levels provides protection against kidney disease the absence of the hormone testosterone contributes to a more rapid progression of kidney disease when diabetes is present. M...
Grapes, soy and kudzu blunt some menopausal side effects
...lyphenols blunt memory loss and hypertension in an animal
model. Study 2: Soy and Hypertension Previous ...a large increase in arterial pressure, putting the animal
at a much greater risk of stroke and other cardiovascular complications. The precise mechanism by wh...
Preclinical study links gene to brain aneurysm formation
...as endothelial nitric oxide synthase (NOS-3) in an animal
model led to intracranial aneurysm formation in 33 percent of study subjects. Scientists say this suggests that the gene may play an important role in the development of intracranial aneurysms. An aneurysm occurs when a blood vessel weakens and...
Lost forest yields several new species
...ests which, so far, have been found to contain six animal
species new to science: a bat, a rodent, two shrew...725 meters above sea level. In addition to the new animal
species, the survey found that the region of gallery forests and woodlands is extremely rich in biod...
High-intensity ultrasound may launch attack on cancer, wherever it lurks
...att School of Engineering. The new findings from animal
experiments suggest that once activated by the ultrasound, the immune system might even seek and destroy cancer cells, including those that have spread through the bloodstream to lurk in other parts of the body. This high-intensity focused ultrasou...
Cornell scientists link E. coli bacteria to Crohn's disease
...rization, said Kenneth Simpson, professor of small animal
medicine at the College of Veterinary Medicine. Our findings raise the possibility that a novel group of E. coli contains opportunistic pathogens that may be causally related to chronic intestinal inflammation in susceptible individuals. They suggest...
American Chemical Society's Weekly PressPac -- Aug. 1, 2007
...N Senior Editor Celia Henry Arnaud, explains that animal
testing long has been the gold standard for enviro...sful, such assays may in the short term reduce the animal
toxicity tests that are necessary and in the long term replace animal
tests entirely, the article st...
Link identified between Alzheimer's disease and glaucoma
... Alzheimer brains can be used to treat glaucoma in animal
models. One such drug, Bapineuzumab, is already being used in clinical trials to treat Alzheimer's patients by pharmaceutical companies Elan in Dublin and Wyeth in the US. However, the UK researchers have shown that when combined with two other novel...
Anthrax bacterium's deadly secrets probed
...rax bacterium secretes equip it to grow only in an animal
host and not in the soil. This finding sheds li..., often fatal, illness when ingested by a suitable animal
host. Bioterrorists have exploited this ability to deadly effect. Dr. Anil Wipat, Professor Colin...
Not all embryonic stem cell lines are created equal
...Before, it was only possible to use mouse or other animal
cells to model neurodegenerative diseases, but the genetic background is so different from that of humans that key aspects of diseases such as Alzheimers could not be reproduced. Both Sun and Sdhof said that their findings have implications for the p...
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