Gene therapy offers new hope for treatment of peripheral neuropathy
...yR-HSV infected animals, while it had no effect on animals infected with vector only. This alleviation of the pain response in GlyR-HSV-treated mice was reversed by the subsequent addition of low concentrations of strychnine, a strong GlyR-specific inhibitor, or antagonist. According to Dr. Glorioso, thes...Scientists discover 5 new species of sea slugs from the Tropical Eastern Pacific
...to yield a wealth of never-before-described marine animals to visiting scientists at the Smithsonian Tropical...d her collaborators two more years to identify the animals in the new collection by comparing them to existing collections, consulting specialists and using a ...Existence of muscle-building stem cells points to regenerative therapies for muscular disease
...o the muscles of mice successfully replenished the animals regenerative reservoir of cells. "Weve found that there are two types of satellite cell90% that are already committed to becoming muscle and another 10% with characteristics normally attributed to stem cells," Rudnicki said. "Its not been shown yet...Lessons from the orangutans: Upright walking may have begun in the trees
...y were on the thinnest branches. When bipedal, the animals also tended to grip multiple branches with their l...r conservation efforts, according to Thorpe. These animals are seriously endangered, primarily due to habitat destruction. "If you can understand how they c......er said anecdotal observations have suggested that animals such as snakes, owls and bees use acoustic mimicry. This study takes the next step and provides the definitive experimental evidence for how mimicking sounds helps an animal survive....A living memory chip, black holes on the loose, and a clearer picture of ocean currents
...n controlling the transport of drifting plants and animals as well as the distribution of nutrients and pollutants that affect ocean life. Researchers at the University of New South Wales in Australia and the Universitat Paderborn in Germany discovered that barriers to currents, which can lead to swirling gy...News tips from the Journal of Neuroscience
...argeted dorsal striatum. The authors studied those animals that displayed motor deficits as revealed by amphetamine-induced rotation, cylinder, and stepping tests. Half of the rats received fetal ventral mesencephalon cell transplants, after which motor performance improved markedly. Next, half of the grafte...New research shows sharks use their noses and bodies to locate smells
...ver, odor itself has no directional properties, so animals must use a variety of senses to get the directiona...uccess rate or plume preference. However, lesioned animals no longer discriminated between sources of turbulent and oozing odor. In the dark, search time of le...Common treatment for methamphetamine overdose may damage brain cells
...urnal of Neuroscience . "This work in laboratory animals raises immediate concerns that a standard treatment for methamphetamine overdose in humans might worsen drug abuse-related brain injuries," says William Carlezon, PhD, at Harvard's McLean Hospital, who was not affiliated with the study. "A crucial ne...Growth factors and environment combine to increase brain maturation
...m is accelerated in an enriched environment, where animals can explore new objects, engage in physical exercise and play. The aim of this research was to clarify the molecular mechanisms that control this phenomenon. Specifically, in this study a molecular factor, called Insulin-like growth factor I (IGF-I...Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...f insects and small crustaceans. It is not only animals that can feel the wrath of C. botulinum, explains Dr Sebaihia: "The soil can be a harsh environment and food can be scarce. To see off the competition, C. botulinum comes with its own antibiotic a chemical called boticin that kills competing bacteri...JCI table of contents: May 24, 2007
...ulin resistance was even further impaired in these animals when they were fed a high-fat diet and the animals were only partially responsive to treatment with TZDs. The study reveals the essential role for PPAR...A nurse makes the decision on who will live
...ositive selection). The genetic alteration in the animals studied results in female mice whose thymocytes undergo positive selection, exclusively, while all thymocytes in male mice are negatively selected. If thymic nurse cells only internalize thymocytes that will be killed and removed, one would expect t...UGA study reveals function of ubiquitous yet poorly understood microorganisms
...e, with bacteria and eukaryotes such as plants and animals on the other two branches. But scientists are just now gaining a fuller understanding of what archaea do in an ecological sense to make a living. A new study led by University of Georgia researchers and announced on Wednesday at the American Soci...Leading the fight against food poisoning
...ncy. Campylobacters are found in poultry and other animals and cause millions of cases of food poisoning worldwide. The researchers intend to develop bacteriophage-based treatments for the control of Campylobacter. Bacteriophages the term literally means bacterium-eater are naturally occurring agents tha...New genetic data overturn long-held theory of limb development
Long before animals with limbs (tetrapods) came onto the scene about 3...bility. According to Shubin, in the Late Devonian, animals like Tiktaalik and its descendants acquired limbs with fingers using this primitive design, largely ...Botulism bug has few genome wrinkles
...f insects and small crustaceans. It is not only animals that can feel the wrath of C. botulinum, explains Dr Sebaihia: "The soil can be a harsh environment and food can be scarce. To see off the competition, C. botulinum comes with its own antibiotic' - a chemical called boticin that kills competing bacte...Bacteria show promise in fending off global amphibian killer
... cryoconitis) has speeded the recovery of infected animals while the other (Pseudomonas reactans) has tended to slow the process, at least on the salamanders. "There will have to be careful testing," say Harris. "Just because on the Petri plate you find a species of bacteria that is anti-chytrid doesn't me...Jefferson scientists use gene therapy to reverse heart failure in animals
...aking it a tailored therapy. After 18 weeks, those animals that received the gene therapy had significantly improved heart function compared to animals that did not receive the treatment. Specifically, the Koch team, including Patrick Most, M.D., and...Plants that produce more vitamin C may result from UCLA-Dartmouth discovery
...ns, vitamin C is also an important antioxidant for animals and plants. Humans do not have the ability to make...s are still studying what VTC2-related genes do in animals and how these genes may relate to aging and cancer. ...