Tag: "antibiotic" at biology news
Inflammation may cause preterm labor and fetal deaths
... from the department of periodontics. Currently antibiotic
treatments are not very effective at preventing preterm births that are triggered by a bacterial infection. Mice, as well as humans, have several toll-like receptors (TLR) that sense the surface components of living or dead bacteria. TLR2 and 4 ar...
Investigating antibiotic use in acute care patients
Pigs could be the key to understanding how antibiotic
resistant bacteria persist in Intensive Care Units...in, says it is commonly believed that each time an antibiotic
is used only pathogens or disease-causing bacteria will be killed. "Antibiotic use in hospitals is...
Instant steam takes on MRSA
...or electricity, promises to be useful for tackling antibiotic
resistant superbugs like MRSA and C. difficile, as well as removing chewing gum from pavements and powering environmentally friendly cars, reports Nina Morgan in Chemistry & Industry, the magazine of the SCI. The value of instant steam lies in creat...
Researchers watch antibiotics, bacteria meet at atomic level
...t from a physiological point of view, not only for antibiotic
design, but also because faults in the complex hav...x. In the second study, the team learned how the antibiotic
streptolydigin blocks transcription. Streptolydigin has been around for several decades and the rese...
News tips from the Journal of Neuroscience
...t the dots between neuroprotection afforded by the antibiotic
minocycline, inhibition of microglia activation, and apoptotic signaling through the p75 neurotrophin receptor (p75NTR). Five days after a contusion injury at T10/11 in adult rats, the spinal cord showed elevated levels of proNGF (nerve growth factor...
HWI researchers determine structure of protein from pathogen associated with CF and TB
...ity to disable this protein and may identify a new antibiotic
that could limit the infections that can be fatal in CF patients, Gulick said. Work from other labs has identified the proteins that are essential to make pyoverdine, the compound that Pseudomonas produces to obtain iron. Some of these proteins ar...
New way to target and kill antibiotic-resistant bacteria found
...ck this enzyme and prevent bacteria from spreading antibiotic
resistance genes, the research shows. Interfering ...very type of bacteria has become more resistant to antibiotic
treatment. These bugs cause deadly infections that are difficult to treat and expensive to cure. ...
Waging war on the deadliest superbug
...ction. This will reduce the selection pressure for antibiotic
resistance that arises from the use of traditional antibiotics. Professor Richard James, Director of CHAI said: We intend to apply for 5m over the next five years to increase the critical mass of researchers drawn from nine schools at The Universit...
Tick-related disease thrives on cholesterol, study suggests
...pects he was bitten by a tick needs to seek prompt antibiotic
therapy. Additionally, lowering cholesterol levels through diet or with medication may help decrease the chance of developing HGA, or at least reduce the severity of its symptoms....
Modified mushrooms may yield human drugs
...hers exposed the mushroom cells to hygromycin. The antibiotic
kills all the normal cells, separating out those that have been genetically altered for resistance. The test demonstrates that if a second gene, insulin for example, were to be patched in the plasmid, that gene would be expressed as well. "There i...
New compound effectively treats fungal infections
...l compounds that could help counter the problem of antibiotic
Staphylococcus aureus hides out in cells
...acteria had died by about four days as a result of antibiotic
treatment, the team still found viable bacteria in their model system two weeks after infection. The findings may help in understanding persistent infections, and in designing new antibacterial drugs. S. aureus has not traditionally been considere...
NIH awards nearly $21 million to fund cutting-edge research equipment
...ressors and their mutants, and enzymes involved in antibiotic
resistance, among others. University of Maryland Biotechnology Institute (Baltimore, Md.) $737,850.A high-speed system for confocal fluorescence imaging, subcellular photolysis, and patch clamp control of single cells will allow scientists to con...
Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...f the competition, C. botulinum comes with its own antibiotic
a chemical called boticin that kills competing bacteria." Genome sequences can tell us a lot about the biology of the organism, but research into clostridia has been hampered by the lack of a good genetic system. Professor Nigel Minton, Professor ...
Resistance genes in our food supply
...od supply may also be carrying genes that code for antibiotic
resistance. Once in our bodies, could they transmi...genetic information, including genes that code for antibiotic
resistance. Horizontal gene transfer between disease-causing bacteria in the hospital setting has a...
UVa researcher studying disease that cripples newborns
...ivated DM when the mice drank water containing the antibiotic
doxycycline. Within a few weeks, the doxycycline caused the mice to begin producing RNA made toxic by extra CTG repeats. The mice became unable to relax their muscles, developed heart rhythm abnormalities and other symptoms of DM1. When researchers r...
Burroughs Wellcome Fund awards $14M to support physician-scientists
...se in Pseudomonas aeruginosa biofilm formation and antibiotic
tolerance Anil Potti, M.D. Duke University Gene expression patterns coupled with signatures of oncogenic pathway deregulation provide a novel approach to targeted therapeutics in non-small cell lung carcinoma Alice Shaw, M.D., Ph.D. Massachus...
Clinical trial data regarding NKTR-061 will be presented at ATS International Conference
...um and tracheal aspirate concentration, safety and antibiotic
reduction properties of NKTR-061. Data will be presented and discussed at this ATS session to show a reduction in the use of IV antibiotics in mechanically ventilated patients during treatment of gram-negative pneumonia with NKTR-061. Further, th...
NIH awards VBI, Mayo Clinic $2.4M to study chronic rhinosinusitis
... cases per year and at least 30 million courses of antibiotic
treatment (National Center for Health Statistics). CRS can produce inflammation of the lining of the nasal sinus. In some cases, this is followed by thickening of sinus mucosa and the formation of polyps or growths in the nasal cavity. Even with aggr...
Scientists discover rare 'gene-for-gene' interaction that helps bacteria kill their host
...s have found that Photorhabdus bacteria produce an antibiotic
which inhibits the work of an enzyme that insects'...known as ST for short. This molecule is also an antibiotic
and Photorhabdus produces it to kill off other microbes that might grow in the corpse of the dead in...
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