Pitt phage hunter takes on tuberculosis
...ull course of treatment, which leads to increasing antibiotic resistance against the disease. More effective treatments could be on the way, however, with a new five-year, $2.8 million grant from the National Institutes of Health to Graham Hatfull, Eberly Family Professor of Biotechnology and Chair of the De...Over-use of antibiotics in fish-for-food industry encourages bacterial resistance and disease
...which can survive in the presence of antibiotics - antibiotic resistant bacteria. Eventually this process could lead to increased antibiotic resistance in the 'disease-causing' bacteria (pathogens) of fish. The properties which make bacteria...Scientists to employ Arctic ice and polar bears to protect diversity of world's crops
...has become increasingly resistant to the two major antibiotic pesticides used to protect the trees. The disease reappeared in Italy in 2005 after six years of absence. Yet the diverse genetic apple resources needed to cultivate resistant apple trees are rapidly disappearing, even in Central Asian where the app...Tips from the journals of the American Society for Microbiology
...minary research has indicated a connection between antibiotic resistance and food of animal origin. Experts are...ial (specifically manure) may play in transmitting antibiotic resistant bacteria to residential settings. Enterococci are commonly found in animal and human diges...Attack is the best defence against urinary tract infection
...As the development of resistance to the body's own antibiotic is very rare, it can be used as an alternative or a complement to conventional antibiotic medication." Urinary tract infection is currently one of the ten most common reasons for outpatient...New potential drug target in tuberculosis
...ures of the molecule that could be targeted by new antibiotic drugs. The results appear in this week's online issue of the Proceedings of the National Academy of Sciences (PNAS). M. tuberculosis is dangerous because it hides and persists in the immune cells of our bodies. "It can only persist there because of t...Innocuous intestinal bacteria may be reservoir for resistance
...o harmless after all. They may be a reservoir for antibiotic resistance genes that can be transferred to more h...in Georgia, there was no association found between antibiotic use and isolation of multi-drug resistant Salmonella. Where does the drug resistance in Salmonella ...New study finds key role for VEGF in onset of sepsis
...with severe sepsis will die in spite of successful antibiotic therapy because the body's host response is out of control and turns on its bearer." Sepsis develops when the immune system becomes overactivated in response to an existing infection, setting in motion a cascade of dangerous inflammatory and coagulat...Tips from the journals of the American Society for Microbiology
...actices can significantly affect the prevalence of antibiotic resistant to bacteria in poultry say researchers f...bacter isolates were tested for resistance to nine antibiotic agents. Researchers found that although Campylobacter species were dominant in both poultry operatio...Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax
...stexposure vaccination can shorten the duration of antibiotic treatment required to protect against inhalational...ttack--is difficult to diagnose early, and despite antibiotic therapy, has a high fatality rate. In addition, because anthrax spores can remain in the body for e...Boosting newborns' immune responses
...iscovered that newborns are deficient in a natural antibiotic called bactericidal/permeability-increasing protein (BPI), produced by white blood cells known as neutrophils. Based on this discovery, clinical trials are now underway at the University of Texas Southwestern Medical Center in Dallas to replace the m...Scientists design potent anthrax toxin inhibitor
...ey could one day be important adjuncts to standard antibiotic therapy for the treatment of inhalation anthrax," ...ll evaluate the inhibitor with and without adjunct antibiotic therapy....Anthrax inhibitor counteracts toxin, may lead to new therapeutics
...ator of the project. "Combining the inhibitor with antibiotic therapy may increase the likelihood of survival for an infected person." The 2001 intentional release of anthrax spores via postal mail in the United States led to increased research on possible therapeutics and vaccines to treat toxins that could be...Researchers now able to look deep into heart to view triggers of a heart's beat
.... Because many commonly used drugs, including the antibiotic erythromycin, decongestants containing epinephrine and anti-depressants, can block potassium channels, any woman in her 30s and 40s can be at risk for drug-induced ventricular arrhythmias, and potentially, sudden cardiac death. "The prevailing view ...FDA grants Accentia Biopharmaceuticals...
...ial super-infection for which more than 40 million antibiotic prescriptions are dispensed annually. The healthcare cost of chronic sinusitis is estimated at greater than $5 billion a year." Accentia is preparing to commence its Phase 3 placebo-controlled clinical trial with SinuNase to treat post-surgical patie...Evolution follows few of the possible paths to antibiotic resistance
...reases bacterial resistance to a widely prescribed antibiotic by a factor of roughly 100,000. Their work indicat...ep mutational paths that theoretically could grant antibiotic resistance, only about 10 actually endow bacteria with a meaningful evolutionary advantage. The rese...Keck Futures Initiative announces grant recipients
...ts, thereby reducing the overuse of broad-spectrum antibiotic regimens and saving numerous lives in hospitals. JOHN WIKTOROWICZ, University of Texas Medical Branch, Galveston CORINNE LENGSFELD, University of Denver, Colorado MICRO INCUBATOR FOR BACTERIAL INFECTIOUS AGENTS - $75,000 Using microelectromechanical...International scientists to present MRSA research in Liverpool
...discuss the latest data on tracking the spread and antibiotic resistance of bacteria that cause disease in hospitals and in the wider community. This data is important to assess whether MRSA strains are increasing or decreasing in number and to provide advice to doctors on how to treat patients that might be a...Highlights of American Chemical Society meeting in Atlanta, March 26-30
...oratory tests, extracts of fresh chives had strong antibiotic activity against 38 strains of Salmonella , one of the leading causes of foodborne illness, according to researchers at North Carolina A&T State University in Greensboro. In the future, chive extracts might provide a natural alternative to irradiati......s and their metabolites can significantly increase antibiotic resistance in the population. Synthetic hormones can act as endocrine disruptors, by mimicking or blocking hormones and disrupting the body's normal functions. The UB presentations will be made as part of a day-long symposium to be held March ...