Studying the chemistry of drugs in wastewater
What happens to painkillers, antibiotics and other medicines after their work is done, and they end up in the wastewater stream? The National Institute of Standards and Technology (NIST) is using laboratory experiments to help answer this question by studying what happens to pharmaceuticals...Antibiotic identified as potential anti-cancer candidate
...ein chain. While work began on the development of antibiotics against what was thought to be a bacterial-exclusi...thus potentially derailing the usefulness of these antibiotics for specifically combating infectious agents. In previous studies, Scheinberg and colleagues had fo...UCLA scientists discover new way to fix defective gene
...ate the disease entirely. The team used a group of antibiotics called aminoglycosides to make the PTCs invisible ...s protein-reading machinery. After bathing in the antibiotics for four days, cells that earlier contained little or no ATM proteins had grown full-length ATM prot...Insects implicated in the evolution of new human infectious diseases
...ently a large problem is that there are a range of antibiotics to treat them and insecticides that help suppress ...stance to insecticides and bacterial resistance to antibiotics unite to throw up new diseases that doctors will have difficulty controlling. In-built similarities ...Paratek Pharmaceuticals presents multiple sclerosis data at Society for Neuroscience annual meeting
...tment with minocycline or any other broad-spectrum antibiotics causes many patients to experience intolerability related to antibiotic side effects. In today's presentation, Paratek will report that three non-antibacterial tetracycline compounds, with different structures, demonstrated activity in reducing limb...Common household fragrances may be harming aquatic wildlife, study finds
... break down." Pharmaceuticals, such as estrogens, antibiotics and antidepressants, often pass through the body without being fully metabolized, Luckenbach noted. "A lot of them are just dumped into the toilet, and that's how they get into the environment." Major industry Worldwide production of synthetic musk...Antibiotic-resistant bacteria increased after clindamycin use for common vaginal infection
...resistance following topical treatment between two antibiotics routinely prescribed for a common vaginal infection, researchers from the Magee-Womens Research Institute have found antibiotic-resistant bacteria more likely to develop with the drug clindamycin than metronidazole. The study is being published in th...International marine survey of coral death
...re limited inoculation is possible -- by including antibiotics in food for aquaculture fish, for example -- the treatment is problematic. "Spillover of antibiotics from fish pens can lead to low doses of antibiotic being delivered to the wider marine ecosystem, wi...In a tiny squid, bacterial toxin governs organ development
...ic microbes to acquire resistance to commonly used antibiotics has been the primary concern. But because the agents kill microbes indiscriminately, microorganisms that play important roles within their human hosts also are at risk. From a scientific perspective, the new findings may encourage r...Molecular technique shows promise in destroying drug resistance in bacteria
...GN, Ill. -- A new approach to outwit resistance to antibiotics has been discovered by a team of researchers at th... to make themselves impervious, such as by pumping antibiotics out of the cell, preventing them from entering the cell or demolishing them. A common way bacteria ...Diamonds are a urologist's best friend
...many kinds of medication less effective; even when antibiotics are used the infection is then often difficult to combat.' In addition to urinary catheters there are also what are known as ureter splints (stents), which are inserted from the bladder right up to the kidney. For example, in ureteroliths or cases of...Acid-resistant bug doesn't give in to alcohol either
... are the bases for developing valuable drugs."Many antibiotics are derived from soil organisms like bacteria that are trying to kill other bacteria," said Kappock. Fortunately, in the case of Acetobacter, any useful enzymes it may provide should be completely harmless, just as it is to humans (besides rui...New study discovers why 'persister' cells never say die
...st Kim Lewis has discovered the gene that prevents antibiotics from successfully destroying infections within bio...) which puts the cell into hibernation and because antibiotics must work on growing cells to destroy them, the hibernating cells can outlast the antibiotic and the...Multidrug-resitant bacteria found to be airborne in concentrated swine operation
.... They detected bacteria resistant to at least two antibiotics in air samples collected from inside a large-scale...Health Sciences. Chapin explained that the use of antibiotics in industrial animal production has a significant impact on the emergence of antibiotic-resistant ba...New weapon in germ warfare: 'Jamming' bacteria signals stops cholera
... "These bacteria have become resistant to many antibiotics and are becoming harder and harder to treat. "Because furanones don't kill the bacteria, there is no selection pressure for them to develop resistance. Indeed, in a million years of evolution, no natural resistance has been developed by bac...New tuberculosis antibiotic may shorten treatment time, fight drug-resistant strains
...ther bacteria, an advantage because less selective antibiotics can generate resistance genes in other bacterial species, and may interfere with the intestinal flora. Next, the researchers tested their compound in mice, finding that one month of treatment with a drug cocktail that included R207910 reduced the bac...Study by US, Hebrew University scientists sheds light on how bacteria persist despite antibiotics
...t so that the persistent cells could be "hit" with antibiotics at the point that they reach a normal growth stage, then perhaps the problem of relapse could be overcome. Alternatively, perhaps further study of the nature of the persistent cells could lead to drugs that would take direct action against them in th...Researchers show how botulism toxin ensnares its target
...ses that have progressed beyond the stage at which antibiotics are effective.Howard Hughes Medical Institute inve...tage botulism or tetanus, noted Brunger, effective antibiotics and vaccines already exist to treat the diseases in most cases, if they are caught early. In further......permanent resistance by bacteria and fungi against antibiotics cannot be prevented in the longer-term. The only solution is to reduce the dependence on antibiotics by using these less. The reduced effectiveness of antibiotics is not only an important issue for hu......uccessfully against other pathogens, the phenazine antibiotics they contain cannot stop B. cinerea. This is because they also activate the production of the BcatrB protein and are therefore immediately pumped back out again. This new information is helpful in developing new strategies to control grey mould disea...