Tag: "aorta" at biology news
Study points to new way to predict death risk from torn aorta
...lots in the channel created when the layers of the aorta
separate like two layers of an onion. This channel...true lumen, which is the hollow middle area of the aorta
that acts as the pipeline for blood to flow out of the heart and down through the abdomen. As blo...
Environment and exercise may affect research results, UA study shows
...ed far fewer regions of disorganized tissue in the aorta
than those housed in standard cages. The evidence suggests that even though the knockout mice were genetically predisposed to arterial damage, simply housing them in an enriched environment, where they could perform their normal functions, reduced...
Hopkins researchers uncover critical player in cell communication
...iated with craniofacial defects, problems with the aorta
and a very specific mental retardation that causes those affected to be talkative, sociable and empathetic but at the same time have significant spatial learning defects. Those affected are highly expressive, have exceptionally strong language abili...
Beyond lipids: understanding the mechanics of atherosclerosis
...ersity, isolated endothelial cells from the bovine aorta
and grew them in culture flasks. They seeded the cells onto silicone rubber membranes that had been coated with a protein that allowed the cells to attach the way they do to underlying blood vessel tissue in the body. They then stretched endothelial ...
Blood pressure medication may revolutionize treatment of Marfan syndrome
...ling in a variety of tissues, including the lungs, aorta
and mitral valve. The next logical step was to see if they could prevent the excessive signaling of transforming growth factor beta. Since aortic aneurysm is the only Marfan syndrome phenotype associated with significant mortality, the researchers ch...
JCI table of contents, March 23, 2006
...rin 3C was dramatically reduced in the SMCs of the aorta
and pulmonary artery. These studies demonstrate that GATA-6 is an important regulator of semaphorin 3C levels in neural crest-derived SMCs during cardiac development, and that further study of this protein may provide insights into the causes of deve...
New research suggests abdominal aortic aneurysm will afflict millions of baby boomers
...ally fatal disease that affects the segment of the aorta
that runs through the abdomen. The most deadly complication is rupture, a condition in which the aneurysm breaks open and profuse bleeding results. To date, however, the exact cause of abdominal aortic aneurysms (AAA) remains unknown, and in its ea...
Study finds significant independent association between air pollution and cardiovascular risk
...herosclerotic plaque in the thoracic and abdominal aorta
and vasomotor tone changes in the mice. They concluded that in a mouse model, long-term exposure to low concentration of PM(2.5) altered vasomotor tone, induced vascular inflammation, and potentiated atherosclerosis. You can read the full study in th...
Inherent vascular repair key to atherosclerosis
...or gene chip, analysis of the activity of genes in aorta
samples from each of the four groups. Using this n...n the disease where the expression patterns in the aorta
begins to change from young VPC to old VPC treatment coincides with the point at which the inflammat...
Researchers learn how blood vessel cells cope with their pressure-packed job
...sts were performed on endothelial cells lining the aorta
of a cow, but the endothelial cells of the human aorta
are expected to react similarly. The stress fibers were made of actin, a fibrous protein that is par...
Gene's mutations found to cause life-threatening aortic disease
...ntified the first genetic mutations that cause the aorta
the body's main artery to widen, tear and ruptur...gical markers that flag aneurysm, a bulging of the aorta
that leads to dissection, a lengthwise separation of tissues in the artery wall, is critically impor...
Why do aneurysms form? New studies suggest leading role for white blood cells
...rgery to repair or replace the swelling section of aorta
before time runs out. But despite the deadly toll ...n the very early stages of AAA formation, when the aorta
wall begins to weaken and bulge. The researchers think the cells may somehow act in combination with...
Inflammatory condition doubles heart attack, stroke risk
... the arteries that supply the brain, heart or main aorta
itself, which can be quite devastating, leading to a stroke or heart attack." Ray and his colleagues from Toronto's Institute for Clinical Evaluative Sciences, report their findings in the March issue of Heart. They compared individuals with GCA to t...
Recognizing new aneurysm syndrome can save lives
... syndrome and rapid surgical repair of the swollen aorta
can save lives, the researchers report in the Jan....ody's biggest blood vessel. In these patients, the aorta
breaks at a much smaller size than it does in people with Marfan syndrome or other causes of aneurys...
Estrogen protects male rats from aortic aneurysms
...disappeared. Every male rat that received a female aorta
developed an aneurysm. "The fact that all the male and female aortas developed aneurysms when transplanted into male rats, compared to only 17 percent of the female aortas in female rats, suggests that host environment is the critical factor in aneur...