Climate change isolates Rocky Mountain butterflies
...s the lead author of a paper on this research that appears today in the Proceedings of the National Academy of Sciences. Roland also said the Parnassius are not currently a threatened species, but they and smaller species native to Rocky Mountain meadows, including some insects and rodents, will suffer "se...Unravelling new complexity in the genome
...ers of the Blencowe lab, Barash has uncovered what appears to be part of a regulatory code that controls alte...w studies is that the alternative splicing process appears to provide a largely separate layer of gene regulation that works in parallel with other important s...Bursts of waves drive immune system 'soldiers' toward invaders
...tin is not only an output of Hem-1 action; it also appears to eliminate the Hem-1 that has assembled it, the ...ht "next door." As each Hem-1 succumbs, a new one appears - but only on one side. Weiner thinks the structure of actin physically blocks Hem-1 from recruiting...Features of replication suggest viruses have common themes, vulnerabilities
...organelle is suspended. The neck is a gateway that appears to permit substrates needed for replication to enter and newly made viral genomes to exit. The virus begins to co-opt the cell as a critical viral protein and viral RNA localize to the budding organelles, Ahlquist explains. "The virus takes over mo...Newly created cancer stem cells could aid breast cancer research
...d cells for use in experiments. The study, which appears in Cancer Cell on August 13, also offers clues about the trajectory of cancer cells. A normal cell is thought to evolve progressively toward a malignant state through a series of genetic mutations. The early alterations confer uncontrolled growth, wh...Doernbecher Children's Hospital scientist earns coveted Javits award
...ls survive, but fail tomature to make myelin. This appears related to a molecule calledhyaluronic acid (HA) that builds up in the damaged white matter andprevents the normal production of myelin. "The oligo-cells are blocked at a critical period in their celldevelopment before they are able to make myelin....Gene regulation, not just genes, is what sets humans apart
...alk that governs when genes are turned on and off, appears to be significantly different. Positive selection, the process by which genetic changes that aid survival and reproduction spread throughout a species, has targeted the regulation of many genes known to be involved in the brain and nervous system...Risk of common vaginal infection linked to preterm birth appears higher for blacks
...a common vaginal infection linked to preterm birth appears to escalate when even one partner is African-American, according to a University of Pittsburgh School of Medicine study presented today at the 34th annual meeting of the Infectious Diseases Society for Obstetrics and Gynecology in Boston. When a pr...deCODE discovers cause of major subtype of glaucoma
...t because the genetics has led us directly to what appears to be the sole cause of a devastating common disea...e the disease. The LOXL1 protein made by this gene appears to play a role in the accumulation of microfibullar deposits that causes XFG, providing a promising ...New molecular regulators of hyperthyroidism and goiter
...protein complex known as Gs. But now, a study that appears online on August 9, in advance of publication in the September print issue of the Journal of Clinical Investigation, indicates that in mice Gq/G11-mediated signaling has an essential role in transmitting TSH-induced signals and therefore in regulatin...JCI table of contents: Aug. 9, 2007
...protein complex known as Gs. But now, a study that appears online on August 9, in advance of publication in t...he anti-apoptotic protein Bcl-2. In a study that appears online on August 9 in advance of publication in the September print issue of the Journal of Clinical...New test improves detection of liver cancer
...alent primary liver cancer. The disease most often appears following a chronic inflammation of the liver as a consequence of a hepatitis B or C virus infection or cirrhosis of the liver. Cirrhosis of the liver comprises a group of liver diseases in which the normal liver cells become damaged and are replaced...Cardio exercise benefits in male vs. female hearts
...he lead researcher, This study finds that exercise appears to help females more than males. The findings bring us a step closer to explaining the sex bias in physical activity that protects the heart....Inflammation may cause preterm labor and fetal deaths
... deaths. Han said the synthetic TLR4 antagonist appears to be safe for mice mothers and their pups. The researchers said they hope to find ways to prevent preterm labor that complicates 12% of all live deliveries and results in 70% of neonatal deaths. Preterm births affect nearly half a million babies...Penn researchers discover how key protein stops inflammation
... for disposal. During exposure to infection, Bcl-3 appears to overrule the p50 ubiquitination, stabilizing th...ntrols the inflammatory response, says Chen. Bcl-3 appears to take in information from the body and, in response to infection, interferes with p50 degradation ...Gene variant is associated with brain anatomy, clinical course of ADHD
...areas of the brain that handle attention, but also appears associated with better clinical outcomes among individuals with the disorder, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals. ADHD is among the most heritable of neuropsychiatric diso...In a first, Einstein scientists discover the dynamics of transcription in living mammalian cells
... at Einstein and senior author of the study, which appears in the August issue of Nature Structural & Molecular Biology. The study focused on RNA polymerase II--the enzyme responsible for transcription. During transcription, growing numbers of RNA polymerase II molecules assemble on DNA and then synthesiz...New mechanism links smoking to lung damage
...e know occurs in many oxidative stress situations, appears to open these channels and allow unregulated flow. This can weaken and kill cells." Cells have multiple membrane channels that carefully control the flow of specific small molecules in and out of the cell, including calcium, sodium and potassium io...A sensory organ, not the brain, differentiates male and female behavior in some mammals
...odies are strikingly different physiologically, it appears the same cannot be said for the brain." Dulac and colleagues are now studying the behavior of male mice mutant for TRPC2 to determine whether they display female-like traits. ......e of Medicine researcher who led the research that appears today in the journal Science. Dictyostelium discoideum usually exists as a single-celled organism. However, when stressed by starvation, the single cells band together to form a slug that can move. Eventually the slug changes to produce cells that ...