Medical informatics project targets ovarian, breast cancers
... the human genome data and powerful bioinformatics approaches out there," said IU cancer biologist Kenneth Nephew, who is leading one of the cancer project's four parts. "In the end, we believe our work will lead to better therapies for ovarian and breast cancer patients." The researchers will study the genetic...Government development policies, not communities, main threat to forest conservation projects
...orld Parks Congress. It dismisses claims that such approaches to conservation 'haven't worked'. Over the past 25 years, says the report, biodiversity conservation has moved from a 'fences and fines' approach based on a system of heavily guarded, protected areas, to a more inclusive way of doing things, in whic...Trojan-horse therapy blocks buildup of Alzheimer's plaque
...companies and by other academic groups using other approaches to inhibiting A aggregation." The next step will be to test the Trojan horse molecules on mouse models of Alzheimer's disease, to determine whether the molecules have a clinical effect on progression of the disease. Crabtree said that the Trojan hors...UGA scientist Moran receives $2.6 million from Gordon and Betty Moore Foundation for marine research
...d other marine science faculty in using these new approaches was a key factor in Moran receiving the Gordon and Betty Moore Foundation grant, said Gordhan Patel, UGA's vice president for research. "We greatly appreciate the foundation's confidence that its support will lead to new insights into the organisms ...BU chemist to map DNA's surface, uncovering details that will show how structure abets function
...A, and to use these experimental and computational approaches to build structural maps of the genome. To build the database, Tullius will expand earlier research efforts to determine patterns of naked DNA using a chemical probe called a hydroxyl radical. These radicals can spot a particular hydrogen atom in a ...Virginia Tech, TIGR sign memorandum for new alliance
...th the unique opportunity to undertake comparative approaches to systems of disease and health across multiple species. Building on those capabilities, Virginia Tech has made commitments to develop structures and provide resources that encourage and support interdisciplinary research in several critical health ...New source for heart bypass replacement blood vessels: Fibrin-based TEVs
...us or plaque formation. Various tissue-engineering approaches were developed using natural or synthetic biomaterials as scaffolds for cell growth. Biodegradable scaffolds using polyglycolic acid (PGA) have shown promise and collagen gels also worked, though 7mm collagen-based TEVs needed Dacron mesh reinforceme...First Max Planck Partner Institute in China
...litate the combining of compiled system-biological approaches with experiments. Due to the proximity to the experimental bioscience institutes in Shanghai and close ties to a number of Max Planck Institutes, the models could be tested and evaluated immediately. The Institute for Computational Biology will round...Tiny exosomes extracted from donor cells may be 'magic bullet' for drug-free transplants
... cells have tolerance-enhancing qualities, several approaches under study involve giving recipients donor dendritic cells that have been modified in some way. The idea is that the modified donor cells would convince recipient cells that a transplanted organ from the same donor is not foreign. "What may be a mo...New program examines stem cells' potential to repair, replace damaged tissue
... basic researchers working together to develop new approaches to treating common diseases. That group is now meeting weekly, preparing to apply for a Program Project grant from the National Institutes of Health which already has a name: "Molecular Mechanisms of Tissue Repair With Aging." Stem cells are relati...Duchenne Muscular Dystrophy research focuses on early mechanisms
...n life so that researchers can develop therapeutic approaches that will blunt or eliminate its onset, said researcher Robert Grange, assistant professor of human nutrition, foods, and exercise in the College of Agriculture and Life Sciences, who will lead a group of scientists from several universities. Working...Academy eBriefings offer comprehensive reports on more than 100 cutting-edge scientific issues
...earch. The promise of nanotechnology. Scientific approaches to the problem of youth violence. Why Californians have higher rates of autism. Neurogenerative diseases and the role of chemical biology in developing new drugs. How scientists are accelerating the development of an AIDS vaccine. Understanding l...Nuclear imaging offers possibility for early detection of patients with coronary heart disease
...eissberg, M.D., stated the need for better imaging approaches and outlined the biology of atherosclerosis, reviewing both invasive and noninvasive (such as 18F-FDG PET) imaging techniques available, especially those that detect metabolic or inflammatory changes within detected plaque. Advances in understanding ......Medicine , say that this insight could lead to new approaches for inhibiting infection as HIV enters the body. Nearly a decade ago, this group of NIH scientists, led by Sharon Wahl, discovered that SLPI, a protein-chopping inhibitor in saliva, could stop HIV from infecting immune cells called macrophages. They...GlaxoSmithKline awards $250,000 in research grants for research on drug therapies for HIV/AIDS
... been awarded to three scientists working on novel approaches to combat HIV, the virus that causes AIDS. The recipients, who will share equally in a total of $250,000 in grant monies, are: Yaoxing Huang, Ph.D., from the Aaron Diamond AIDS Research Center; Olaf Kutsch, Ph.D., from the University of Alabama at ...How receptors govern inflammatory pain
...gests their potential relevance in the therapeutic approaches toward the prevention and treatment of chronic inflammatory pain. Bettina Hartmann, Seifollah Ahmadi, Paul A. Heppenstall, Gary R. Lewin, Claus Schott, Thilo Borchardt, Peter H. Seeburg, Hanns Ulrich Zeilhofer, Rolf Sprengel, and Rohini Kuner: "The A...Studies suggest promising new directions for gallstone treatment
...al Institute researchers. The findings suggest new approaches to developing drugs to prevent the disease, which afflicts some 20 million people a year. The studies also propose novel strategies for developing diagnostic tests to identify people with a genetically increased risk for developing gallstones. A rese...A new species of amyloid peptide
... the brain emerges as one of the possible rational approaches for the treatment of Alzheimer's disease. Generally, amyloid β-peptides are around 39-43 amino acid long. Studies have shown that the longer amyloid β-peptides are more amyloidogenic and more pathogenic than the shorter ones. Now, Dr. Xu an...MBL scientists embark on international effort to uncover microbial diversity in world's oceans
...crobes is a mega-science problem that requires new approaches to mapping diversity, grand strategies, integration of diverse communities, and enabling studies that will explore processes--whether ecological or evolutionary," said Sogin. "A problem of this magnitude requires careful planning and international c......abine alone. "There are many different approaches to post-remission therapy, and they include using fewer cycles of high-dose cytarabine or reducing the dose of the drug, but our study suggests these treatments are inferior," Farag says. At the same time, the study suggested that using ...