Unlocking proteins from their cellular shell
...n the current issue of the journal Science. Cells are exposed to forces every minute of every day. Some forces are exerted by the flow of bodily fluids, such as blood streaming through arteries, while other forces a...Discredited Korean embryonic stem cells' true origins revealed
...ates the egg (meiosis), the duplicated chromosomes are not actually identical, but have places where the ...pecially toward the ends of the chromosomes, which are more likely to exchange genetic material, rather than the middle. In contrast, embryonic stem cells ...Unknotting DNA clue to cancer syndrome
...amily of DNA-unwinding enzymes, or helicases, that are involved in repairing DNA. Neil Hunter, assistan...as a template for the damaged one. The DNA strands are then exchanged to form four-way structures called Holliday junctions. To complete repair, these junc......tricate DNA repair mechanisms in the cells' nuclei are constantly working to fix what's broken, but wheth...Association, have found evidence that indeed there are specific regions where broken DNA is concentrated for repair. "NASA has long been interested in ...News tips from ACS Chemical Biology
...an Chemical Society journal, ACS Chemical Biology, are now available on EurekAlert!, Below is a link to the July 2007 edition. In the current issue Toxins from snails may lead to new drugs New strategies for minimizing the side effects of the COX inhibitors,(some of which were banned due t...Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer
... stability have observed that many kinds of cancer are associated with areas where human chromosomes brea...arises when they do not heal correctly and instead are deleted or rearranged, Freudenreich explained. "Cancer cells almost always have some sort of deletio...Chickadee, nutchatch presence in conifers increases tree growth, says CU-Boulder study
...e said. "The study indicates that pine canopies are very complex systems with an unexpected level of b...hes can help improve the heath of the trees, which are the monarchs of the forest," said CU-Boulder biology Professor Yan Linhart. Linhart was Mooney's doc...New strategy for treating allergic disorders
..., if our immune system is not working properly, we are subject to a variety of diseases. In the case of a...eritis. The initial results of the clinical trials are promising. Now, the bacterium is also being used to fight other disorders. There are a number of a...Success or failure of antidepressant citalopram predicted by gene variation
...respond to the medication citalopram (Celexa) than are people without the variation, a study by the Natio...lead to a better understanding of which treatments are likely to work for each patient. Results of the study are in the August issue of the American Journa...Coelacanth fossil sheds light on fin-to-limb evolution
...il record to the first members of that group, they are really different and very diverse. Until now, ma...h relatives of tetrapods (lungfish and coelacanth) are both highly specialized, according to Friedman. Both groups acquired many of the same specialization...Neurosciences and music meet in Montreal
...into the main themes. Also included in the program are two poster sessions. The conference organizers encourage all members of the Neuromusic Community to participate in the development of the conference program by submitting proposals for symposia on specific topics that actively contribute to the res...A low expression of MX2 gene exists in the white blood cells of narcoleptics
...fering from narcolepsy, or another sleep disorder, are urged to consult with their primary care doctor or a sleep specialist....Marijuana component opens the door for virus that causes Kaposi's sarcoma
... these cells into malignancy. While most people are not at risk from Kaposis sarcoma herpes virus (KSH...s, such as AIDS patients or transplant recipients, are more susceptible to developing the sarcoma as a result of infection. Their findings, reported in th...Altering a protein makes mice less fearful
... that ASIC1a is concentrated in brain regions that are critical for fear behaviors and responses, includi...brains, where it is found in the amygdala. There are no known mutations of the ASIC1a gene linked to altered fearfulness, but the UI study raises the pos...COX-2 inhibitors delay pancreatic cancer precursors in mice
...Eibl, most researchers agree that stage III PanINs are a direct precursor to pancreatic cancer in humans as well as mice. Between 12 and 15 months, Dr. Eibl says the majority of KrasG12D mice will develop pancreatic tumors. The UCLA researchers divided the mice into two groups one set received a nimes...Phase II study of therapeutic vaccine shows efficacy in patients with metastatic colorectal cancer
...nger signals associated with a viral infection, we are demanding that the immune system take notice, Harr...ccinations. According to Harrop, the researchers are currently testing the vaccine in a phase III trial in renal cancer patients in the U.S. and Europe a......ost serious and potentially deadly when its spores are inhaled. Bergmans team focused on the mystifyin...at chance exists for a few hours when the invaders are inside immune cells in the lung and then pass from the lungs to the lymph nodes. Once the bacteri...Einstein researchers' prototype vaccine could provide improved protection against tuberculosis
...sthe organism that actually causes TB in humansand are knocking out certain genes to yield a live, attenuated M. tuberculosis strain that still produces a strong immunological response that protects people. TB bacteria invade human cells and then--successfully evading a persons immune response--lurk in...Progesterone injections do not prevent preterm birth in twin pregnancies
...el Hill. The mechanisms that lead to preterm birth are complex, and I think our current study shows they ...amenable to a single solution. The study results are published in the Aug. 2 issue of The New England Journal of Medicine. The lead author is Dwight J. R...Handicapping tuberculosis may be the way to a better vaccine
...ates that approximately 2 billion people worldwide are infected with TB, with over 95 percent of infectio...nues to circulate throughout the body. These cells are known as memory T lymphocytes, and will be poised and ready should the pathogen appear again. The mo...