Phase II study of therapeutic vaccine shows efficacy in patients with metastatic colorectal cancer
...ay attention to this molecule, so by producing 5T4 artificially in combination with the danger signals associated with a viral infection, we are demanding that the immune system take notice, Harrop said. TroVax causes cells at the injection site to produce 5T4 in a way which agitates the immune system into pro...Smithsonian's National Zoo researchers use electronic eggs to help save threatened species
... species. Temperatures and turning frequencies for artificially incubating eggs can sometimes rely as much on guesswork as on hard data. Improving the success rate of breeding not only increases the numbers of birds in captive populations, but also helps maintain their genetic diversity, which is essential for a ...Ability to listen to 2 things at once is largely inherited, says twin study
...right ear and tried to identify the word. One test artificially filtered out high-pitched sounds, which tended to obscure the consonants, while the other sped up the word. In all but the filtered-words test, researchers found a significantly higher correlation among identical twins than fraternal twins, indica...New collaborative research reveals chimpanzees can sustain multiple-tradition cultures
...rative work of the last five years, showing we can artificially introduce cultures in chimpanzees, which supports the idea cultural variation observed in the wild is learned, says Dr. de Waal. We are the first to show cultures potentially can jump from group to group if you offer chimpanzees the opportunity to wa...Largest synthetic gene ever built offers insights into anti-malarial drug resistance
... in the past three decades. They have been able to artificially construct, and then express in yeast, a protozoan gene that contributes to such resistance. And it was no small feat. The gene they laboriously constructed over a two-year period is believed to be the largest “synthetic” one ever built, and it succes...PET/CT use expands: Effectively diagnosing graft infections
...l. She said that prosthetic grafts are inserted to artificially restore and ensure blood circulation through the obstructed blood vessels to areas that would otherwise suffer from the lack of sufficient blood supply. "Graft infection is an uncommon but potentially severe complication following prosthetic vascular...New data on the probiotic strain Bifantis shows anti-inflammatory properties
...determined that only Bifantis delayed the onset of artificially induced arthritis and resulted in less severe arthritic symptoms. This study represents some of the latest work assessing the link between diet involving probiotics and certain autoimmune diseases. In the second study, mice were fed Bifantis a...FSU engineering professor growing bone in a lab
...a long-term proposition. "We're not going to see artificially created bone tissue being transplanted into human patients by this time next year," he said. "Stem-cell research still is in its very early stages, and we have a great deal more research to do -- and regulatory hurdles to overcome -- before this is r...Pediatric cancer stem cell identified: understanding the origin of ERMS
... therapeutic targets of human ERMS. The scientists artificially activated the RAS pathways to induce ERMS in a strain of genetically engineered zebrafish. Some transgenic zebrafish developed visible tumors by 10 days of age. Through their model, Dr. Zon and colleagues were able to identify both an ERMS tumor-c...Tips from the Journals of the American Society for Microbiology
...able to those of the reference culture method with artificially inoculated pork meat and poultry samples," say the researchers. "The main advantage of the method developed is the reduced time of analysis, enabling faster release of Salmonella-free fresh meat." (M.H. Josefsen, M. Krause, F. Hansen, J. Hoorfar. ...Spud origin controversy solved
...ut also for breeders. Years of effort were made to artificially recreate the European potato from Andean landraces yet it may have originated from Chile, said Spooner. If the true origin of the European potato was from Chile, rather from the Andes, it shows the value of plant evolutionary studies to understand an...Enhanced environment restores memory in mice with neurodegeneration
...d that using drugs to increase histone acetylation artificially produced an effect very similar to that observed in environmental enrichment," said Tsai. "This leads us to believe that further studies of ways to target chromatin remodeling could offer a treatment for Alzheimer's and other forms of dementia," she ...UCLA/Toronto researchers unlock key to memory storage in brain
...ns of the new research could prove profound. "By artificially manipulating CREB levels among groups of cells, we can determine where the brain stores its memories," he explained. "This approach could potentially be used to preserve memory in people suffering from Alzheimer's or other brain injury. We may be a...A 'traffic light' for neurons means 'go' for improving brain research
...wn the road, Deisseroth speculates, the ability to artificially stimulate neural signals, such as movement instructions, could allow doctors to bridge blockages in damaged spinal columns, perhaps restoring some function to the limbs of paralyzed patients. Finally, the technique could be useful in teasing out th...30th anniversary of the Heinz Maier-Leibnitz Prize
...the young field of optical metamaterials. They are artificially produced materials characterised by the fact that they refract incoming light to the left. All natural materials, such as glass, refract light rays to the right. Linden was the first to succeed in developing left-handed metamaterials for the short wa...RNA enzyme structure offers a glimpse into the origins of life
...obertson said. The structure indicates that this artificially selected ribozyme uses reaction mechanisms that are much like those used by naturally occuring enzymes, Robertson said. "The L1 ligase appears to use strategies of transition-state stabilization and acid-base catalysis similar to those that exist ...First direct electric link between neurons and light-sensitive nanoparticle films created
...ticle-based artificial retina. Nanoparticles are artificially created bits of matter not much bigger than individual atoms. Their behavior is controlled by the same forces that shape molecules; they also exhibit the bizarre effects associated with quantum mechanics. Scientists can exploit these characteristics ...Carnegie Mellon researcher proposes development of artificial cells to fight disease
...llon University's Philip LeDuc predicts the use of artificially created cells could be a potential new therapeutic approach for treating diseases in an ever-changing world. LeDuc, an assistant professor of mechanical and biomedical engineering, penned an article for the January edition of Nature Nanotechnology J...Taking heart failure to the MAT1
...n cells that lacked MAT1. Even when the scientists artificially increased the amount of PGC-1 in the cells, its function was decreased if there was no MAT1. Ultimately, the investigators proved that MAT1 binds to PGC-1 and forms a physical complex with it, providing a direct biochemical explanation for the abil......c of damaged DNA under the microscope. Then they artificially supplied the cultured cells with one of two genes-either a functional copy of the WRN gene, which is mutant or nonfunctional in Werner Syndrome, or a gene encoding the protein telomerase, which elongates short or missing telomeres. After cells divide...