Tag: "assembly" at biology news
Bursts of waves drive immune system 'soldiers' toward invaders
...f-generating waves of Hem-1 control the pattern of assembly
of building blocks of a second protein, actin. Thi... scientists observed the Hem-1 activation of actin assembly
and actin's inhibition of Hem-1 accumulation. The "recruitment" component was not directly observed,...
Doernbecher Children's Hospital scientist earns coveted Javits award
...d hiswork has been singled out by this very senior assembly
of distinguishedneurologists and neuroscientists," said Mark Richardson, M.D., M.B.A.,dean, OHSU School of Medicine....
A unique arrangement for egg cell division
...mice. In the current issue of Cell they report the assembly
of this machinery, which is very different from wh...spindle without such centrosomes. Tracking spindle assembly
over time with a high resolution microscope in live mouse oocytes, Ellenberg and his PhD student Mel...
Weizmann Institute scientists discover a control mechanism for metastasis
...ellular structure. The cells internal skeleton an assembly
of densely-packed protein fibers comes apart and the protein fibers then form thin threads on the outside of the cell membrane that push the cell away from its neighbors. In addition, a number of protein levels change: some get produced in higher qu...
Unlocking proteins from their cellular shell
...logic action and reaction in living things. Their assembly
and reactions are the foundation of processes from... often reflect changes in protein organization and assembly
that adversely affect static and dynamic forces in, on, and around cells. Protein targeting is the...
Scientists discover new way to study nanostructures
...rnett, report that when a microfabricated junction assembly
is held below its superconducting transition temperature, unusual features are found in traces of the electrical conductance measured as a function of the applied voltage. In our experiments, only nanowires - which we know now to contain a single d...
Scientists to make news at Computational Biology Conference
... accomplishments will dot the landscape at a giant assembly
of computational biologists in Vienna in mid-July. From new ways to discern how DNA folds into cell nuclei to possible treatments for diseases such as cancer, both basic and applied biology are getting a boost from researchers who call themselves bio...
Penn researchers discover how microRNAs control protein synthesis
...e manufacturing of proteins to begin. However, the assembly
of proteins quickly comes to a standstill when the miRNA-Ago2 complex binds near the back end of a messenger RNA. By analyzing the amino acid sequence of Ago2, Kiriakidou and others uncovered a similarity with the cap-binding domain of the EIF4E prot...
JCI Table of Contents -- July 2, 2007
...y synthesized excess alpha-globin, but also in the assembly
and stabilization of normal amounts of hemoglobin, even when alpha-globin is deficient, indicating unique and previously unidentified roles for this molecule. In an accompanying commentary, Arthur Bank from Columbia University discusses the identif...
Surprising origin of cell's internal highways
...ll directions to the cell's periphery. Their rapid assembly
and disassembly helps transport proteins throughout the cell and generate polarized (directional) signal distribution that causes cells to move. While microtubules in some specialized cells can originate from non-centrosomal structures, the centro...
Exploring the dark matter of the genome
... unique or sufficiently distinctive sequences. The assembly
was checked by matching it to clones of longer sequences. With the painstaking manual assembly
taken as far as practical, the researchers mapped the sequences to their physical locations on the c...
Crammed with charged DNA, pressure rises inside virus
...pumps its DNA into the capsidouter shellduring the assembly
process. The potential energy of the tightly coiled DNA may help phi29 inject its genetic material into the bacterial cells it infects. Now a team led by physicists at the University of California, San Diego has used laser tweezers to measure the f...
Anti-inflammatory drugs interact with HRT, and more
...ple round bumps on cell surface represent sites of assembly
and budding of virions. Credit: C. Goldsmith/CDC CONTACT: Andrew Yates Emory University Department of Biology 1510 Clifton Road Atlanta, GA 30322 United States of America +1 404 727 1765 email@example.com Related PLoS Medicine Perspective article...
Newly identified mechanism for silencing genes points to possible anti-cancer strategies
...his molecule is known to interfere with the proper assembly
of ribosomes, which prevents them from doing the w...iekhattar says. "If so, the eIF6 would prevent the assembly
of a competent ribosome, thus blocking messenger RNA translation at that gene. The result would be t...
Decoding protein structures helps illuminate cause of diabetes
...nderstand the pathological protein mis-folding and assembly
that seem to underlie a host of human disorders, including diabetes and Alzheimer's disease. Now, chemists at the University of Wisconsin-Madison have designed a powerful analytical tool capable of measuring molecular structures quickly and accur...
DOE JGI sets 'gold standard' for metagenomic data analysis
...tion, labeling, and ultimately sequencing. Genome assembly
is the process of putting the sequenced fragments ..., for example, when using the widely used sequence assembly
tool Phrap, they actually saw artifacts created by the program caused by mixing sequences that shoul...
Story ideas from the Journal of Lipid Research
...Orlean and Menon review the latest findings on GPI assembly
in the ER, its transfer to a protein, and the changes made to GPI on its way to the cell membrane. They describe the enzymes and chemical reactions involved and highlight questions that need to be addressed, especially how GPI structure affects the p...
Work with nanoparticles may lead to 'on-the-spot' virus detector
...t."In the research, the UB engineers used directed assembly
to tailor dielectrophoretic forces, which act through a nonuniform electric field, overcoming an obstacle that occurs whenever nanoparticles are involved. "When you work with microscopic objects dispersed in a liquid, gravity is very important," ex...
New clues for treatment of disease that causes accelerated aging
... clipped off is erroneously deleted during initial assembly
of the protein. That leaves lamin A stuck to its guide molecule, which in turn is stuck in the nuclear membrane. Scientists believe this misplacement causes progeria; under the microscope, it leads to visible distortions in the structure of cell nucl...
MNI researchers find a new role for mitochondria in cellular copper regulation
...oteins, SCO1 and SCO2, which are necessary for the assembly
of COX," says Shoubridge. To characterize the roles of SCO1 and SCO2, Shoubridge and colleagues looked at cells that contained mutated forms of either one or both of these molecules. The study shows that both proteins have a role in maintaining th...
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