Heterochromatin assembly in S. pombe
...ilencing. The authors purified the heterochromatin assembly protein, Rik1, along with two novel Rik-1 associated proteins that proved essential for H3-K9 methylation and centromere silencing. Intruigingly, they also found a novel Rik1-associated E3 ligase that is necessary for heterochromatin assembly. "Thes...DNA constraints control structure of attached macromolecules
...ther efforts, we would like to control macroscopic assembly processes by influencing the shapes of self-assembling molecular components."...The making and breaking of microtubules
...ein from which microtubules are formed) during the assembly and disassembly of microtubules. Details of these ... goal was to understand the process of microtubule assembly and disassembly." "Our current work actually revealed the structures of different tubulin assemblie...ASU researcher fashions DNA to further advances in nanotechnology
...ime been envisioned as scaffolds for directing the assembly of biomolecules such as proteins into a functional... one-billionth of a meter. By programming into the assembly a short sequence of DNA that recognizes a particular protein, called an aptamer, Yan created a DNA m...For first time, brain cells generated in a dish
... as Parkinson's disease or epilepsy. "It's like an assembly line to manufacture and increase the number of brain cells," said Bjorn Scheffler, M.D., a neuroscientist with UF's College of Medicine. "We can basically take these cells and freeze them until we need them. Then we thaw them, begin a cell-generating...From memory formation during sleep to novel components for physics
..., or for copy protection, selective production and assembly control or for determining the causes of machinery malfunctions. (Spokesperson: Prof. Berend Denkena, University of Hannover) Bridges, cranes and aeroplanes are made of complex space frames, which consist of elements that are either welded, riveted, ...Gram-negative bacteria shoot their way into cells
...ing that functions as a molecular platform for the assembly of the secretion system. The greatest excitement about the new atomic structure comes from the potential to selectively target a type of disease-causing bacteria, the researchers said. "Part of why this is so important is that antibiotics are becomin...Rock on! Indiana limestone: NIST's first and latest SRM
...indshields, tires, and transmission gears to final assembly and subsequent operation. Prosaic limestone is a critical natural resource. In addition to being a building material, it is used in the manufacture of lime for agricultural and chemical processes, cement and concrete, and iron and steel. NIST resear...Same fold in viral shells point to common ancestry
...tein fold of the viral envelope is crucial for the assembly of the capsid, which protects DNA vital to a virus' ability to infect host organisms and reproduce. The T4 and HK97 viruses are called bacteriophages because they infect bacteria. "In the case of the T4 virus, the capsid is made of interconnected six...High fidelity keeps human DNA assembly line humming
...urton explains that it is similar to an industrial assembly line, with DNA being a conveyer belt to load build...on said it does not mean mistakes never occur. The assembly line analogy holds up there. The human system has an acceptable level of error required to allow for...New thermometer reveals wet conditions on earliest Earth
...istory of the Earth and have been used to date the assembly and movement of continents and oceans. "Zircons allow us to go further back in geologic time because they survive processes that rocks do not," said Watson. "Although they measure only a fraction of a millimeter in size, zircons hold a wealth of inf...Washington University chosen as NIH Program of Excellence in Nanotechnology
...ix specific aims of the Program Preparation and assembly of programmed, integrated nanosystems Application of nanostructures for imaging at increased levels of sensitivity Imaging of gene expression by recognition of messenger RNA (mRNA) transcription products Application of the nanostructures for the......he architecture of the receptors, resulting in the assembly of a large, springy molecular scaffolding between the receptor towers. The interlocking system grips and pulls the receptors towards each other until they collapse inward like overloaded laundry lines. The stressed receptors become engulfed by the ce......l states in any photoactive system, macromolecular assembly or nanostructure. "This technique should also be useful in studies aimed at improving the efficiency of molecular solar cells," Fleming said. In the Nature paper, he and his colleagues describe how they successfully used 2-D electronic spectroscopy ...Scientists discover that host cell lipids facilitate bacterial movement
.... Because Listeria is capable of stimulating actin assembly and PIP2 and PIP3 are known to localize to regions... only at the very back of Listeria where new actin assembly was taking place," recalls Dr. Southwick. "To our surprise these lipids also localized to the front ...Harnessing microbes, one by one, to build a better nanoworld
...N DIEGO - Taking a new approach to the painstaking assembly of nanometer-sized machines, a team of scientists ...the great challenges of nanotechnology remains the assembly of nanoscale objects into more complex systems," says Robert Hamers, a UW-Madison professor of chemi...Shutting down the HIV assembly line
...of itself. New HIV particles roll off the cellular assembly lines, burst like bubbles out of the cell, and flo... combat HIV infection by shutting down the virus's assembly lines. For several years, Paul W. Spearman, M.D., associate professor of Pediatrics and Microbiology...Dental researchers answer key enamel question
...y of the amelogenin nanospheres, and their further assembly into nanosphere arrays, forms its own scaffold that can direct the alignment of the mineral crystallites."...Insects, viruses could hold key for better human teamwork in disasters
...arch in information technology to enable the rapid assembly and deployment of ad hoc, flexible networks of responders who act largely on the basis of local information. Such a strategy would be enormously helpful in helping us cope with disasters such as the recent tsunami in the Indian Ocean." One of the way...Fritz Lipmann lecture will look at enzyme biosynthesis of peptide natural products
...omal peptide synthetases. These synthetases act in assembly lines to carry out initiation, elongation, and termination reactions. Once released from these assembly lines, the peptides are often tailored by enzymes that glycosylate, oxygenate, and halogenate. Dr. W...