NIH gives $8M to University of Pittsburgh School of Medicine for myositis research
...d adults diagnosed with polymyositis, which is not associated with a rash. The study doctors want to know whether rituximab improves symptoms of these diseases. Rituximab is a monoclonal antibody used and approved since 1997 by the Food and Drug Administration (FDA) for the treatment of B-cell non-Hodgkins l...Unravelling new complexity in the genome
...c functions in the nervous system, including roles associated with memory and learning. However, in most cases the investigators working on these genes were not aware that their favorite genes are regulated at the level of splicing. Blencowe believes that the data his group has generated provides a valuable bas...Does the desire to consume alcohol and tobacco come from our genetic makeup?
... identify sex-specific and non-specific linked and associated areas. Summary of Results The researchers rep...4, inside gene GRID2, researchers found linked and associated SNPs for smoking moreover they found associated SNPs inside these gene for alcohol in males f...No evidence that widely prescribed statins protect against prostate cancer
...estosterone, for total testosterone, and for other associated compounds. The researchers found no relationship...in use and free testosterone and most of the other associated compounds. There was a significant association between statin use and level of total testosterone in...Climate change and permafrost thaw alter greenhouse gas emissions in northern wetlands
...wever, the report also cautions that this flooding associated with collapsing permafrost also increases methane emissions. Methane is an important greenhouse gas, which is more powerful than carbon dioxide in its ability to trap heat in the earths atmosphere. Turetsky said it seems the permafrost degradatio...Genetic variation helps to understand predisposition to schizophrenia
...e that produces a protein called Neuregulin 1 were associated with schizophrenia, but how the Neuregulin 1 gene ...lleagues found that one of these DNA variations is associated with increased expression of a novel type of Neuregulin 1 called type 4 one of the six known types ...Gilbert Foundation and American Fed for Aging Research award grants on Alzheimer's disease
...o more than 25 diseases that have been shown to be associated with protein misfolding and aggregation, including Parkinsons disease and type II diabetes. Grace Stutzmann, Ph.D., Assistant Professor, Rosalind Franklin University: "Contributions of early calcium signaling dysregulations to Alzheimer's disease...A study by the MUHC and McGill University opens a new door to understanding cancer
...ant advance in our understanding of the mechanisms associated with cancer and contributes to the fight against the disease by directing us towards research avenues for new medications. ...New study suggests Concord grape juice may provide protection against breast cancer
...ells. Diets high in natural antioxidants have been associated with a reduced risk of some types of cancers, and Welchs 100% Grape Juice made from Concord grapes is particularly high in anthocyanins, potent natural antioxidants that give the juice its characteristic deep purple color. At the same time, drinking ...JCI table of contents: Aug. 9, 2007
...e than normal mice. These effects on behavior were associated with decreased signaling in the hypothalamus through a protein known as PPAR-alpha. Administration of a PPAR-alpha agonist into the hypothalamus increased the amount mice lacking FAS specifically in the beta-islet cells and in the hypothalamus ate bu...Brain blood flow gives clues to treating depression
... depression, while electroconvulsive treatment was associated with additional decreases in blood flow, he report...dicines that target different neurotransmitters is associated with a similar improvement in cerebral blood flow, he noted. However, cerebral blood flow continued ...Sugar and spice and everything nice: Health differences in newborn girls and boys
...r H+ level within 60 minutes of ischemia. This was associated with a significant 13 percent greater accumulation of lactate. They also found the CP reserve was 22 percent lower than baseline compared to males. Based on these and other findings the investigators concluded that, for this study: male and fe...The 'female advantage' in kidney disease does not extend to diabetic women
...woman to develop renal disease at levels generally associated with her male counterpart" Researchers at Georget...s in which they determined that: diabetes is associated with reduced estrogen (estradiol) levels, which may explain why the females lose the protective fact...Grapes, soy and kudzu blunt some menopausal side effects
...n, studies have shown that extensive use of HRT is associated with significant adverse effects. As a result, alt...earch team examined whether grape polyphenols were associated with reduced cognitive dysfunction and a lower incidence of high blood pressure. They found that the...Weizmann Institute scientists discover a control mechanism for metastasis
...but swift and deadly form of the disease, which is associated with elevated growth factor levels. The scientists...rotein. High levels of this protein, in turn, were associated with cancer metastasis to the lymph nodes the first station of migrating cancer cells as they sprea......s they relate to African tropical biodiversity and associated economic activities in these regions. The migration of large mammals over large distances is a prominent yet threatened occurrence. Using remote sensing and landscape modeling, researchers can describe and predict major landscape changes that may ...Preclinical study links gene to brain aneurysm formation
...ock out) one of three genes and molecular pathways associated with vascular disease: inducible nitric oxide synthase (NOS-2), endothelial nitric oxide synthase (NOS-3) or the plasminogen activator inhibitor (PAI-1). To determine whether absence of the genes resulted in an increased rate of aneurysm formation...Link between sunspots, rain helps predict disease in east Africa
...cluding the influence of climatic disturbances not associated with sunspots. The researchers, who represent fi...ks may affect rainfall. The increased solar energy associated with sunspots, they suggest, heats both land and sea, forcing moist air to rise and triggering preci...Cornell scientists link E. coli bacteria to Crohn's disease
...ia such as salmonella, cholera, bubonic plague is associated with intestinal inflammation in patients with Croh...d to tubercle bacillus that has been more commonly associated with Crohns....Gene variant is associated with brain anatomy, clinical course of ADHD
A variant of the dopamine receptor gene may be associated with attention-deficit/hyperactivity disorder (ADH... the brain that handle attention, but also appears associated with better clinical outcomes among individuals with the disorder, according to a report in the Augu...