Tag: "asymmetric" at biology news
Research into the sense of touch in worms wins Eppendorf/Science Prize
.... Her Ph.D. project, completed in 2001, focused on asymmetric
cell division and the generation of cell diversity in the embryonic murine cerebral cortex. She is now a postdoctoral fellow in Dr. Sally Temple's laboratory working on mechanisms regulating neural stem cell self-renewal and cell fate choices, includ...
Findings challenge Darwinian theory
...iation, at least when it comes to the evolution of asymmetric
forms" Dr. Palmer said. He was able to synthesize published evidence showing that the current 'genotype-precedes-phenotype' theory of evolution only explains about half of the examples he studied. He came to his conclusions after reviewing more ...
For yeast, a DNA break ensures sex switch for a grandchild
...locus was responsible for generating two rounds of asymmetric
division. Now Benoit Arcangioli's group at the Pas...general implications for how DNA can be marked for asymmetric
inheritance that can affect cell destiny. ...
Scientists uncover secret to sharp teeth
...s secrete enamel, the molecular signals regulating asymmetric
ameloblast differentiation from the underlying den...ast differentiation. The researchers conclude that asymmetric
expression of follistatin accounts for the distinct patterning of enamel formation in mouse incisors...
Asymmetric organs and microRNA-directed DNA modification
...lation of critical genes that guide development of asymmetric
leaf patterning depends on microRNA-directed gene inhibition via DNA methylation. MicroRNAs are a class of very small genes that do not code for proteins but instead act as regulators that can inhibit gene transcription. The new paper shows that in...
Interaction between stem cells and their niches key to differentiation
...e stem cells," Lin said. "Stem cell division is an asymmetric
process. After division, one daughter cell remains attached to the niche cell and thus remains as a stem cell, whereas the other daughter cells is detached from niche cells and will thus acquire a different fate." Lin's team determined three differe...
Vitamin A's paradoxical role in influencing symmetry during embryonic development revealed
...min A) is the signal that buffers the influence of asymmetric
cues in early-stage embryonic stem cells and allow... embryo, because its signaling influences both the asymmetric
arrangement of organs and tissues in the interior of our bodies and the symmetrical pattern of the e...
Brain size may depend upon how neural cells are cleaved
...etermine how Gβγ is regulated. Studies on asymmetric
cell division in fruit flies and roundworms had implicated a particular class of proteins -- known as AGS3 and mPins in mammals -- as upstream regulators of G proteins. The researchers' analyses showed that AGS3 is, indeed, expressed in progenitor c...
Wnt signaling in polarized cell divisions
...apers in the August 1 issue of G&D investigate the asymmetric
localization of beta-catenin (WRM-1) during polarized cell divisions during C. elegans development. Dr. Craig Mello and colleagues used conditional mutants that disrupt Wnt signaling to analyze the moleculaes involved in Wnt-dependent differential nu...
Rockefeller researchers show evidence of asymmetric cell division in mammalian skin
...published online last week in Nature detailing how asymmetric
cell divisions are essential for skin development....unctions and is one of the first documentations of asymmetric
cell division in mammals. The epidermis of the skin forms multiple layers, the outermost of which is...
Substance lining blood vessels may cause cardiovascular disease
...ccess journal PLoS Medicine looks at the role of asymmetric
dimethylarginine (ADMA), which is found in the vessel lining of healthy people but at much higher levels in those with medical conditions associated with damage to the blood vessels. ADMA is already recognized to be an important indicator of cardio...
Figuring out the ups and downsand sidewaysof neural development
... test whether spindle orientation is essential for asymmetric
stem cell divisions as well. If so, this will be an important factor in exploring the regenerative capacity of these cells."...
USC researchers track down the stem cells that create feathers
...rphologies by producing molecular gradients and/or asymmetric
cell behaviors. While this insight into the formation and regeneration of feathers is fascinating, it is the potential for application to human stem-cell studies that really motivates Chuong and his team. "What we are really learning about is how ste...
Life leaves subtle signature in the lay of the land
...Dietrich said. "Without life, there would still be asymmetric
mountains." Their conclusion, that the relative frequency of rounded versus angular landforms would change depending on the presence of life, won't be testable until elevation maps of the surfaces of other planets are available at resolutions of a fe...
Forsyth scientists gain greater understanding of how embryos differentiate left from right
...g embryos. H+-flux across plasma membranes is thus asymmetric
at the four- and eight-cell stages, and this asymmetry requires H+-V-ATPase activity. Artificially equalizing the asymmetry in H+ flux, by increasing or decreasing it on both sides equally, both randomized the location of the viscera without causing ...
News tips from The Journal of Neuroscience
... raised an antibody to Vangl2 and demonstrated its asymmetric
expression at cellcell boundaries between cochlear hair and support cells. In looptail mice that harbor a mutation in Vangl2, polarization failed in the cochlea and in vestibular sensory epithelium. A yeast two-hybrid screen revealed an interaction b...
Mouse, frog and bird put Snail and Slug to different uses
...n both body sides, most internal organs exhibit an asymmetric
distribution. For example, in mammals the heart is...irds, the Snail gene controls acquisition of these asymmetric
body differences in mice. On the other hand, Gridley and Murray found that Snail family gene functi...
FSU biologists uncover mechanisms that shape cells for better or worse
...lecular mechanism that causes cell polarity -- the asymmetric
shape or composition critical to a cell's proper functioning. Their findings in fruit fly eggs may help to clarify how muscular dystrophy and some cancers develop in humans. That's because many of the genes involved in the cell-to-cell communicatio...
16 outstanding researchers receive Singapore's highest honor in science and technology
...nd his colleagues at IBN have prepared a series of asymmetric
catalysts with high activity and selectivity for pharmaceutical synthesis. He is now utilizing nanoporous materials for biomedical applications, such as the separation of proteins, the controlled release of drugs and the regeneration of bone tissue. ...
The pull of bacterial chromosome segregation
...at found in eukaryotic anaphase that mediates the asymmetric
segregation of bacterial DNA. Dr. Waldor emphasizes that "The presence of mitotic machines in bacteria suggests that the basic elements for eukaryotic mitosis evolved before the appearance of multicellular organisms."...