Touching research: How white blood cells navigate
...n't. The same is true of much heart disease, where atherosclerosis occurs when white blood cells cause blockages by narrowing blood vessels. Understanding how forces affect white blood cells offers a new way to fight many of these diseases. Doctors might be able to funnel cells directly where they're needed, allowi...Experimental lupus drug may also work against atherosclerosis
...rosclerosis. In addition to the coronary arteries, atherosclerosis also occurred in the aortic arch, part of one of t... with mice given an inert substance, the amount of atherosclerosis deposited in the aortic arch was cut in half. The TSA-treated mice also ha...Gene linked to greater risk of heart disease in type 2 diabetes
...ial wall. All are major players in contributing to atherosclerosis -- the dangerous buildup of plaque that can lead to partial or complete blockage of the artery, leading to heart attack or stroke. In the first part of this study, the researchers mapped the structure of the CD36 gene, which consists of hundreds of n...Elevated inflammatory enzyme, Lp-PLA2, significantly linked to ischemic stroke
...ved to trigger a cascade of inflammatory events in atherosclerosis can independently predict increased risk of stroke...n. CRP is another inflammatory protein involved in atherosclerosis that can independently indicate risk of cardiovascular disease. Atherosclerosis, the underlying ...Study links polycystic ovary syndrome with early vascular changes of heart disease
...omen with PCOS and subsequent subclinical coronary atherosclerosis observed at the nine-year follow-up," she added. Perhaps most interesting, however, was a finding that higher blood levels of testosterone were associated with increased risk of aortic calcifications in all women, whether they had an endocrine ...Nuclear imaging offers possibility for early detection of patients with coronary heart disease
...l play an increasing role in both the detection of atherosclerosis (coronary heart disease) and, more specifically, t...t advances in understanding of the pathobiology of atherosclerosis have highlighted the inadequacies" of imaging the disease with X-ray angiography. John R. Davies, B....Concord grape juice increased HDL, lowered inflammatory marker linked to heart disease
...and is thought to contribute to the development of atherosclerosis and vascular inflammation. We have seen in previous studies of healthy subjects that drinking grape juice decreases superoxide production and inhibits platelet aggregation, yet its impact on the inflammatory properties of platelets had not been prev...Down Syndrome protein reduces tumor growth
...least in part--for the reduced risk for tumors and atherosclerosis in this patient population." This connection betwe...k for solid tumors and inflammatory states such as atherosclerosis may eventually be used for therapeutic gain in non-Down syndrome patients. "The development of metho...New findings in innate immunity may lead to treatments for atherosclerosis
...n of the anti-inflammatory cytokine IL-10. Because atherosclerosis patients often have elevated IL-10 levels, IRAK1 m... innate immunity regulation," says Dr. Li. Because atherosclerosis patients usually have elevated serum IL-10 levels, the scientists also looked at IRAK1 levels in blo...JCI table of contents, December 1 2004
...ers to investigate the effects of PPAR agonists on atherosclerosis in mice. While studies have shown that PPARgamma agonists are beneficial in the treatment of atherosclerosis in mice, the role of other members of this protein family have remained unclear. In the December 1 i...Columbia study suggests brushing your teeth may reduce risk of stroke and heart attack
...le with gum disease are more likely to suffer from atherosclerosis a narrowing of blood vessels that can lead to str...ux and his colleagues showed that in these people, atherosclerosis is associated specifically with the type of bacteria that causes periodontal disease, and not with o...Study finds direct association between cardiovascular disease and periodontal bacteria
...ic inflammation or infection could have led to the atherosclerosis of the carotid arteries. He and his colleagues n...int, we can better evaluate the progression of the atherosclerosis and, hopefully, begin to establish a time frame underlying the diseases," said Ralph Sacco, M.D., M...Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries
...ic application of AIM regulation for prevention of atherosclerosis in the future. Most importantly and attractively for patients, this approach may not need dietary restriction." Dr. Miyazaki, associate professor in the Center for Immunology and of pathology, and his colleagues first discovered the protective role o...Aspirin is safer than warfarin and just as effective for treating blocked arteries in the brain
... of Medicine.* Intracranial stenosis is caused by atherosclerosis -- fatty deposits that build up on the inner walls of the arteries and restrict blood flow. Intracranial stenosis causes about 10 percent of the 900,000 strokes and transient ischemic attacks (TIAs) in the United States each year. TIAs are transien...Cranberry juice modulates atherosclerotic vascular dysfunction
...lar function in patients with high cholesterol and atherosclerosis is critical to helping protect these patients from...ed: "We're lucky to have a unique animal model for atherosclerosis familial hypercholesterolemic (FH) swine, whose genetic defect causes them to spontaneously develo...14 highlighted physiology papers from IUPS 2005: From 'genomics to functions'
...lar function in patients with high cholesterol and atherosclerosis is critical to protect them from consequences such as heart attack or stroke. "Cranberry juice modulates atherosclerotic vascular dysfunction." Physiology 387.14. Kris Kruse-Elliott and Jess Reed, University of Wisconsin-Madison School of Veterinary ...Thumbnail sampler of 10 diverse physiology papers from IUPS 2005
...r the findings highlight key roles for PKC beta in atherosclerosis development. The studies suggest that atherosclerosis may be affected by the inhibitor of the protein, ruboxistaurin, which is in clinical trials. "Chron...Altering steroid receptor genes creates fat burning muscle
...ulator of inflammation. Coronary artery lesions or atherosclerosis are thought to be sites of inflammation. Dr. Evans...that PPARd drugs could be effective in controlling atherosclerosis by limiting inflammation and at the same time promoting improved physical performance. Dr. Evans s...JCI table of contents May 1, 2005
...n) the vessels Vascular calcification occurs in atherosclerosis and is commonly seen in aging, diabetes, kidney disease, and a host of other physiological abnormalities. It can lead to amputation and cardiovascular disease in patients with type 2 diabetes. In a study appearing online on April 14 in advance of th...Animal study: Compounds in cranberries may have heart-healthy effects
...sel function in patients with high cholesterol and atherosclerosis is critical to helping protect these patients from consequences such as heart attack or stroke. "The next step is to determine what specific components of cranberries are most important to the improvements in vascular function that we observed, exact...