Researchers publish first marsupial genome sequence
...e born at an extremely early stage of development, attach to their mother's teats and complete their subsequent development while in a protective pouch. This makes the young readily available for early developmental research. There are many other areas of biomedical research for which Monodelphis serves ...Researchers attach genes to minichromosomes in maize
... to create engineered minichromosomes in maize and attach genes to those minichromosomes. This discovery opens new possibilities for the development of crops that are multiply resistant to viruses, insects, fungi, bacteria and herbicides, and for the development of proteins and metabolites that can be used ...Flaws in colonoscopies may increase risk of colon cancer
...s were largely due to adhesions (scar tissues that attach to the surfaces of organs, n=512), impassable stenosis (narrowing of the gut, n=506), long and curved colon (n=284), and additional complications (n=50). While male and sedated patients were more likely to have a complete colonoscopy, older patients...Story ideas from the Journal of Biological Chemistry
...eins called microtubules to which they naturally attach and then started aggregating. The scientists then showed that cells in which tau proteins aggregated could not grow and function properly. These results suggest that tau aggregation is toxic to cells and could directly contribute to the progressiv...Cellular message movement captured on video
... Tumor-causing versions of signaling molecules may attach to paxillin and disturb the normal adhesion and growth factor signaling steps required for controlled proliferation and cell growth. For example, human papilloma virus, which can cause cervical cancer, makes a protein that binds to paxillin and that ...... in exosomes are the ability to clump together and attach to the cells membrane, Gould says. In one experiment, Gould and his team added chemicals to normal human cells that force nearby proteins together into a clump, and this was enough to get them sent out of the cell in exosomes. If they added a teth...University of Pittsburgh scientists find new contributor to aggressive cancers
...type of tissue together. Integrins also help cells attach to one another and are involved in transmitting chemical signals between cells and the ECM. In this study, the researchers, led by Jianhua Luo, M.D., Ph.D., associate professor in the division of molecular and cellular pathology, University of Pit...Bacteria ferry nanoparticles into cells for early diagnosis, treatment
...se conditions." When the cargo-carrying bacteria attach to the recipient cell they are engulfed by its outer membrane, forming "vesicles," or tiny spheres that are drawn into the cell's interior. Once inside the cell, the bacteria dissolve the vesicle membrane and release the cargo. The method might be ...New compound effectively treats fungal infections
... of enzymes called aminoacyl-tRNA synthetases that attach the correct amino acid to each tRNA. Some of these enzymes have two main functional parts, or active sites: a site that links the amino acid to the tRNA, and a separate editing site that proofreads this process and removes wrongly added amino acids. ...Targeting key proteins of carcinogenesis
...that the cooperation of three enzymes is needed to attach Ub to another protein: E1, E2 and E3. E1 activates Ub and transfers it to E2, which in turn cooperates with an so-called Ub ligase (E3) that couples Ub to a specific target protein. However, Dikic and colleagues discovered that certain proteins can b......the entire particle, which offers the potential to attach chemicals to the exposed surface for targeting applications. The researchers have learned that particles adhered to red blood cells can escape phagocytosis because red blood cells have a knack for evading macrophages. Nanoparticles arent the first ...Pairing nanoparticles with proteins
...sts have demonstrated the ability to strategically attach gold nanoparticles -- particles on the order of billionths of a meter -- to proteins so as to form sheets of protein-gold arrays. The nanoparticles and methods to create nanoparticle-protein complexes can be used to help decipher protein structures, ...Nanoparticles hitchhike on red blood cells: a potential new method for drug delivery
...the entire particle, which offers the potential to attach chemicals to the exposed surface for targeting applications. The researchers have learned that particles adhered to red blood cells can escape phagocytosis because red blood cells have a knack for evading macrophages. Nanoparticles arent the first ...'Modular' leukemia drug shows promise in early testing
... The study shows that the agent can successfully attach to the protein on the leukemia cells and kill them. The agent works both by triggering the cells' self-destruction and by causing a particular class of immune cells to attack them. In an animal model, the agent worked equally as well as the drug r...Doing nature one better: Expanding the genetic code in living mammalian cells
...ding amino acids Wang selected the one that would attach a desired artificial amino acid to a tRNA that recognizes one of the stop codons. Every time the stop codon appeared in the genetic code, the new tRNA would insert the artificial amino acid. But doing the same trick in mammalian cells becomes way ...Tiny tweezers and yeast help St. Jude show how cancer drug works
...discovery using the magnetic tweezers technique to attach one end of a double-stranded DNA molecule from a magnetic bead while securing the other end to a glass surface. They then rotated a tiny magnet over the top of the magnetic bead, which in turn rotated the bead holding the DNA, twisting the DNA into s...Loss of hemlocks will affect water dynamics in southern Appalachian forests
...ressed by land managers. Hemlock woolly adelgids attach themselves to the base of the needles of the eastern hemlock, feeding on carbon fixed by the trees, slowing growth and causing the needles to drop. Needle loss causes the crown of the tree to thin and dieback in branches; in a surprisingly short time...A stepwise retreat: How immune cells catch pathogens
...e and upon contact with a suspicious particle they attach to it and immediately retract to pull the particle towards the cell body, says Holger Kress who carried out the research at EMBL and is now working at Yale University. We expected the tentacles to move in a continuous, smooth process, but surprisingl...CU researchers discover evidence of very recent human adaptation
...genes that control proteins that help muscle cells attach to surrounding cells (mutations of this gene lead to muscular dystrophy), receptors that relate to hearing, genes involved in nervous system function and development, immune system genes and heat shock genes. The gene scan method also detected select...Satellite tracking will help answer questions about penguin travels
... University of Washington scientists will attach satellite tracking devices to the backs of six pen...unta Tombo. Epoxy and special tape will be used to attach a transmitter to each bird before it is released into the Atlantic. The tags are about the size of m...