Scientists find a maturity gene
...receptor." Hormones like estrogen and testosterone attach to these receptors, which in turn attach to genes in cell nuclei to switch the genes on or off. Nuclear hormone receptors are found in all an...Unweaving amyloid fibers to solve prion puzzles
...sary to understand how the prions that comprise it attach to each other. Krishnan was able to identify the precise segment at which the prions interact--something that no one had done before him with a real prion. To do this, Krishnan took a variety of yeast prion strains and modified them in such a way th...NJIT student named Fellow by NJ Commission on Science and Technology
...er wear the device all day, using adhesive tape to attach it to either their back or chests. Or they can leave the device at home and use it a few times a day to check their conditions. The device will alert them if their conditions worsened and they could then send the data, via a wireless, Internet-based ......hose activity is to be analyzed. The RNA molecules attach to their complementary DNA counterparts on the slide. The amount of mRNA, as measured by fluorescence, reflects a gene's activity. However, such mass gene expression profiling is all but impossible with miRNAs because their short sequences are not as...Tagging pathogens with synthetic DNA 'barcodes'
...g cells consists of two complementary strands that attach to one another along their length. But Luo's research purposely and completely ignores the DNA's genetic coding properties. He uses DNA, he said, as a "generic instead of a genetic material." By synthesizing three short strands of DNA, each of which ...Promiscuous catalytic activity possessed by novel enzyme structure
...l number of molecules, this new enzyme was able to attach prenyl groups to most of the different aromatic compounds tested. Some of the newly-formed hybrid molecules had previously been found in natural sources, but the enzyme also built some new compounds that had never been seen before. The key to Orf2's...ASU researcher fashions DNA to further advances in nanotechnology
...an's work is novel because it makes it feasible to attach any desired biomolecule onto DNA nanostructures. Such work is an important step and can serve as a future foundation for biocatalytic networks, drug discovery or ultrasensitive detection systems. "Rationally-designed DNA nanoscale architectural mo...Purdue scientists may have found key to halting spinal cord damage
...nts - such as vitamins C and E - which are able to attach themselves to free radicals, detoxifying them. While there is nothing inherently wrong with this approach, Shi said, it might not be getting at the root of some health problems. "Antioxidants are good scavengers of free radicals, and it's certainly w...Scripps scientists identify target of an immune suppression molecule called CD22itself
...lves the action of enzymes known as kinases, which attach chemical groups known as phosphates onto the B-cel...rong. Paulson and his colleagues designed a way to attach a common type of cross-linking agent known as a "photoaffinity label" to the sialic acid that would ...Researchers debut new X-ray resources for studying molecules
...he structures of viruses and proteins and how they attach to other molecules will help researchers develop drugs that block those interactions. "The properties of these X-ray beams are even better than we envisioned," said Charles Edmonds, Ph.D., NIGMS scientific director for the interagency project. "They...DNA constraints control structure of attached macromolecules
...ded RNA. Through specific chemical reactions, they attach two strands of DNA, each resembling one side of a ladder. The two DNA strands spontaneously bind together, then the researchers add magnesium ions to initiate folding of the RNA. "Folding of the RNA structure competes with formation of the DNA constr...Protein structure initiative advances to rapid production phase
...ese include small protein complexes; proteins that attach to a cell's outer envelope, or membrane; and many proteins from higher organisms, including humans. "We've already made great technological strides that have enabled us to determine more than 1,100 protein structures during the first half of the PSI...Argonne receives $50 million NIH grant
...ese include small protein complexes; proteins that attach to a cell's outer envelope, or membrane; and many proteins from higher organisms, including humans. "We've already made great technological strides that have enabled us to determine more than 1,300 protein structures during the first half of the PSI...North & South American researchers find architectural abnormalities in T. cruzi ribosome
..."For instance, the splice leader of the mRNA might attach at the turret, which may swivel out and drag the mRNA across the binding site on the ribosome to initiate protein translation." The findings may also advance studies of parasitic relatives Trypanosoma brucei, which causes sleeping sickness in Africa,...UF researchers test drug that could cut orthodontic treatment time in half
...en and elastin fibers to be like rubber bands that attach to the tooth to hold it in place," said Wheeler. "Those tissue fibers resist the force of the orthodontic treatment applied to move the tooth, and, when that force is removed, say when the braces are taken off, the elasticity of the tissues springs t...42 biomedical scientists worldwide named HHMI international research scholars
...family of parasitic protozoa called Apicomplexa to attach themselves to and actively invade host cells. Proteases are enzymes that break down proteins into peptides and amino acids. The parasite Toxoplasma gondii, which causes toxoplasmosis, will be used to do functional, biochemical and structural analyses...Why do aneurysms form? New studies suggest leading role for white blood cells
...rats that lacked the protein that lets neutrophils attach to tissue and start the "first aid" process. The r...n on the surface of neutrophils that allow them to attach to tissue. They studied L-selectin production in the aortas of rats that had been injured with elast...Scientists discover more about how cancer cells form and grow
...ell, the scientists explain how cancer tumor cells attach themselves to a protein on the surface of cells lining blood vessel walls. When this attachment happens, it tells the cancer cell to grow and develop blood vessels, which feed the cell. Cun-Yu Wang, senior author on the paper, said this discovery cou...New lead reported in tumor angiogenesis
... trigger angiogenesis, tumor cells also physically attach to a protein displayed on the surfaces of cells that line the walls of our blood vessels. This physical interaction, like a finger pushing a button, sends a signal within these cells to grow and sprout new capillaries. The finding, while tech......r sequence of the S. pyogenes rRNA. The probes attach to the target rRNA sequence when the test tube is placed in a water bath for about 25 minutes at exactly 41 degrees Celsius (106 Fahrenheit). At that temperature, the complementary probe DNA sequence binds to the target RNA sequences. In a positive ...