Under magnetic force, nanoparticles may deliver gene therapy
... it to cells, added Levy. As a nonviral method, it avoids the unwanted immune system responses that have occurred when viruses are used to deliver gene therapy. Levy said his team would pursue further studies into the feasibility of using the nanoparticles for gene therapy in blood vessels damaged by vasc...Insulin grown in plants relieves diabetes in mice; UCF study holds promise for humans
...ulin because that crop can be produced cheaply and avoids the negative stigma associated with tobacco. The National Institutes of Health provided $2 million to fund the UCF study. The findings are reported in the July issue of Plant Biotechnology Journal. Insulin-dependent, or Type 1, diabetes is an a...Researchers discover method for identifying how cancer evades the immune system
One of the fundamental traits of a tumor how it avoids the immune system might become its greatest vulnerability, according to researchers from the University of Southern California. Their findings, demonstrated in human breast and colorectal cancers, indicate that a technique for determining a tumors ...New tool for marine conservation
...nct species composition. The classification, which avoids significant limitations of older schemes, is based on organisms found both in the sea and on the sea bottom and is considered likely to be useful out to a depth of 200 meters. Coastal and shelf waters have greater species numbers and higher productiv...Nanoparticles hitchhike on red blood cells: a potential new method for drug delivery
...ls to extend the circulation time of the particles avoids the need to modify the surface chemistry of the entire particle, which offers the potential to attach chemicals to the exposed surface for targeting applications. The researchers have learned that particles adhered to red blood cells can escape pha......ls to extend the circulation time of the particles avoids the need to modify the surface chemistry of the entire particle, which offers the potential to attach chemicals to the exposed surface for targeting applications. The researchers have learned that particles adhered to red blood cells can escape pha...American Chemical Society's Weekly PressPac -- May 30, 2007
...son (SB-Tn) system, a gene therapy technology that avoids the pitfalls of transferring genes with viruses, shows promise in laboratory experiments for correcting the gene defect responsible for sickle cell disease (SCD), scientists in Minnesota are reporting. In the study, scheduled for the June 12 issue ...Creation of an international industrial chair in life cycle assessment
...mption, one of the main benefits of LCA is that it avoids the transfer of pollution from one life cycle stage to another or from one type of pollution to another. It represents an interesting analytical framework at the time of investing in a new technology or process but also in the implementation of an en...Smallpox outbreak: How long would it take for vaccines to protect people? Would it work?
...onse to the infection, which lessens or completely avoids the symptoms of illness." Unlike some other diseases, getting vaccinated following exposure to smallpox could provide protective effects. For example, for the flu vaccine to work, people need to get vaccinated before being exposed to influenza. The...MIT bioengineer advances survival, promise of adult stem cells
...ypes of cells she investigates. However, she also avoids research with human embryonic stem cells following a personal experience with in vitro fertilization almost 10 years ago. "Like some other scientists I know, my personal views about creating human ES cell lines changed when confronted with the rea...Penn researchers replace organ in adult mice using 'single-parent' stem cells
...not destroying a viable embryo in the process also avoids certain ethical issues that currently surround embryonic stem cell science." McLaughlin and his colleagues report their findings in the Feb. 15 issue of the journal Genes & Development. "While previous research has approached the possibility of u...Sea creature's toxin could lead to promising cancer treatment
...nt anti-cancer drug, but its unique mode of action avoids the kinds of side effects that make cancer chemotherapy so difficult. It's a great example of how NIH support for fundamental chemical research can benefit the American health-care consumer." The animal, Diazona angulata , is a sea squirt a few in...Getting one's protein in a bunch -- When quality control fails in cells
... neurological diseases. But exactly how the cell avoids such mistakes has remained unclear until now. Researchers at Ohio State University found the mechanism that prevents such errors, and explain their findings in the Proceedings of the National Academy of Sciences. "Cells normally make a certain amou...Stealth technology maintains fitness after sex
...-NS-like stealth protein (called Sfh), the plasmid avoids interfering with the natural balance of H-NS and DNA in the cell," explained Professor Dorman. "Our work suggests that bacterial fitness can be manipulated by altering the proportions of H-NS and DNA in the cell, perhaps through the use of drugs, an...Leading cause of US food-borne illness makes its own pathway through cells
...s in the United States enters cells of the gut and avoids detection and destruction, according to a presentation at the annual meeting of the American Society for Cell Biology in San Diego in December. While scientists are just beginning to answer basic questions about how Campylobacter jejuni (campylobact...Herceptin plus chemotherapy significantly increases disease-free survival in breast cancer
...tained with a non-anthracycline regimen, TCH, that avoids the significant cardiac damage found when Adriamycin is used with Herceptin," said Slamon, director of clinical/translational research at UCLAs Jonsson Cancer Center. "This trial should impact the way early stage breast cancer is treated, with TCH be...Tips from the Journals of the American Society for Microbiology
...iruses and the identification of variola virus and avoids false-negative results in a single reaction tube. (C.G. Fedele, A. Negredo, F. Molero, M.P. Sanchez-Seco, A. Tenorio. 2006. Use of internally controlled real-time genome amplification for detection of Variola virus and other Orthopoxviruses infect...Nobel Laureate finds 'elegant' explanation for DNA transcribing enzyme's high fidelity
...he scientists didnt know either how the polymerase avoids substituting the NTPs that constitute DNA for the correct RNA building blocks, molecules that differ by only one oxygen atom. In search of an explanation in the current study, the researchers screened hundreds of crystals to achieve higher data qual...Story tips from the Department of Energy's Oak Ridge National Laboratory, November 2006
...uces the dimensionality of data in real time. This avoids the problem of too much stored information, which over time can crash systems. This project, designed to identify threats to the U.S., is funded by the Department of Homeland Security. [Contact: Ron Walli, (865) 576-0226; wallira@ornl.gov ]...