Same fold in viral shells point to common ancestry
...the phi 29 virus, which attacks the soil bacterium bacillus subtilis, possesses a protein fold in its capsid similar to the fold found in the HK97 virus, which infects E. coli bacteria. Researchers used a technique called cryoelectron microscopy to determine the three-dimensional structure of phi 29 down to a...Global commitment of Max Planck researchers
...ols to study immune responses against the tubercle bacillus during natural infection in endemic populations in Africa, the impact of progressive HIV-1 infection and its treatment and changes during vaccination with BCG and novel vaccine candidates. The Project Consortium consists of 15 laboratories in Africa...Dangerous tricksters: Some bacterie use immune cells to reproduce
...hodococcus equi is closely related to the tubercle bacillus (Mycobacterium tuberculosis). Since macrophages are the main target of Rhodococcus in the horse's lung, a lot of rhodococci are found there during an infection. In the Bonn Institute of Cell Biology Eugenia Fernandez and Marco Polidori in Professor ...Innovative research set to push boundaries of cancer care
...he only widely used bacterial treatment to date is bacillus Calmette Gurin (BCG) for superficial bladder cancer. Researchers at the University of Illinois at Chicago, however, have found that an opportunistic bacterium, Pseudomonas aeruginosa, that grows in the soil and marshes but is often found in the lung...Newly identified mechanism helps explain why people of African descent are more vulnerable to TB
...anism by which human macrophages kill the tubercle bacillus has remained an additional puzzle. Innate immunit...hages were stimulated by molecules of the tubercle bacillus that trigger Toll-like receptors, the research team found that cells cultured in serum provided by A...National Institutes of Health funds $13.7 million for Texas tuberculosis study
...rld's population is currently infected with the TB bacillus and about 1.7 million died of TB in 2004, according to the WHO's latest figures. Sacchettini's research team, which collaborates with 90 laboratories in 15 countries, uses protein crystallography, a method of examining molecules three-dimensionally t...Tuberculosis: The bacillus takes refuge in adipose cells
...t Pasteur has recently shown that the tuberculosis bacillus hides from the immune system in its host's fat cel...r fighting tuberculosis. Attempts to eradicate the bacillus entirely from infected individuals should take these newly identified reservoir cells into account....UA researchers identify new adherence factor, Pili, produced by tuberculosis
...y. If M. tuberculosis pili are important for the bacillus to establish infections in humans, as with other m... produced by M. tuberculosis, which may enable the bacillus to colonize and grow within the human host, the UA experiments demonstrated that when the gene for p...Will the plague pathogen become resistant to antibiotics?
...eral antibiotics has also been found in the plague bacillus Yersinia pestis, gene sequence researchers report....the multiresistance plasmid acquired by the plague bacillus is widespread in environmental bacteria reinforces this warning". There have been many plague epid...Handicapping tuberculosis may be the way to a better vaccine
...stronger immune response than the current vaccine, bacillus Calmette-Gurin (BCG). The new vaccine improves survival of infected animals and may help put scientists on track to replace BCG, which has been used for nearly a century although it is largely ineffective. Despite widespread vaccination programs, the......es instead of MAP, a bacterium related to tubercle bacillus that has been more commonly associated with Crohns....