Study explains how pathogens evolve to escape detection
... Cornell and BTI scientists describes how a single bacterial protein, AvrPtoB, which is injected by P. syringae into plant cells through a kind of molecular syringe, can overcome the plant's resistance. Normally, the plant's defense system looks out for such pathogens and, if detected, mounts an immune respo...Tips from the Journals of the American Society for Microbiology
...tramuscular vaccinations had significantly reduced bacterial loads and no detectible H. pylori in the intestina...g promise as a better choice for treatment of some bacterial and fungal infectious diseases. In the study researchers identified a novel parasiticidal peptide ...Immune system 'escape hatch' gives cancer cells traction
...DSCs in suppressing the immune response to stress, bacterial and viral infections, organ transplantation and autoimmune diseases. Their goal, researchers say, is to find some means of accelerating or slowing down T-cell activity gone awry....A new plant-bacterial symbiotic mechanism promising
...s. The researchers sequenced (3) the genes of two bacterial strains of Bradyrhizobium, ORS278 and BTAi1, in order to find out their genetic make-up and identify the genes involved in this rather special form of symbiosis. These bacteria were found to have no nod genes, usually essential for nodulation. Bradyr...Citrus greening continues to spread in citrus growing areas
...the most serious threats to the citrus industry. A bacterial disease, citrus greening affects all types of citrus species and causes infected trees to yellow, decline, and possibly die within a few years of infection. Spread by an insect, the Asian citrus psyllid, citrus greening has significantly impacted cit...New research shows vaginal bacteria vary among healthy women, need customized treatment
...n suffer from insidious health problems, including bacterial vaginosis and yeast infections, and those problems...: there are at least eight kinds of normal vaginal bacterial communities, each community is different, and, among the eight kinds of communities, some bacterial ...Maynard Olson receives $500,000 Gruber Genetics Prize
...m a complication: chronic lung inflammation from a bacterial infection they acquired in early childhood. Olson ...om the one which invaded decades, and thousands of bacterial generations, before. And that means effective treatment should also be different. He says, The futur...MIT, BU team builds viruses to combat harmful 'biofilms'
... such as antibiotics are not as effective on these bacterial biofilms as they are on free-floating bacteria. In some cases, antibiotics even encourage bacterial biofilms to form. Lu and senior author James Collins, professor of biomedical engineering at BU, ...Waging war on the deadliest superbug
...lueprint of C.diff, and have an inkling as to what bacterial factors might be important in disease, we have been unable to test these ideas. You never really know what a particular factor is doing until it isnt there. You need to be able to inactivate, knock-out, the gene responsible, and then see if the bac...Reap what your ancestors sowed
... step will be to test the ideas from his models in bacterial systems....Antibody linked to MS significantly higher in spinal fluid of blacks
...or. Scientists believe MS is likely triggered by a bacterial or viral infection. The infection causes an abnormal response in the immune system that misdirects the body's defenses against myelin, a protective sheath that surrounds many nerve cells. To help clinch a diagnosis of MS, clinicians often test the s...More swimmers means more pathogens in the water
...hat water be tested for E. coli and enterococci as bacterial indicators of fecal contamination. Monitoring for E. coli and enterococci may not be reliable in monitoring for waterborne protozoan pathogens, said Graczyk....Doing nature one better: Expanding the genetic code in living mammalian cells
...omes way more complicated. Simply transferring the bacterial genes into mammalian cells doesnt work since they flat out refuse to produce bacterial tRNAs. While it is easy to screen large numbers of mutated aminoacyl-tRNA synthetases in bacteria an......eactive and potentially fatal immune response to a bacterial infection - MIF concentrations are 10 to 20 times higher than normal. If MIF goes down, the chance that patients will survive sepsis is increased dramatically. The idea is to suppress inflammation so that cells stop producing MIF, said Dr. Al-Abed. ...UCF professor finds bacterial pathogen may be key to understanding cancer development
...a Microbiology Professor Keith Ireton is using the bacterial pathogen Listeria Monocytogenes to understand the mechanisms of cell growth and cancer development. In research published this month in the Journal of Biological Chemistry, the team found that a Listeria protein called InlB induces internalization ...Gut check: Tracking the ecosystem within us
...he team used microarrays to profile the mixture of bacterial DNA in an average of 26 stool samples per infant o...nflicting studies about Bifidobacteria, a group of bacterial species reputed to have beneficial effects. Some studies have shown that it is more common in the in...Modified mushrooms may yield human drugs
...o hygromycin, an antibiotic, to circular pieces of bacterial DNA called plasmids, which have the ability to multiply within a bacterium known as Agrobacterium. The hygromycin resistance gene is a marker gene to help sort out the transgenic mushroom cells from the non-transgenic cells, Dr. Romaine explained...Invertebrate immune systems are anything but simple, conference finds
.... Insects recognise peptidoglycan [a component of bacterial cell wall] and this triggers a rapid immune response explains Schmid-Hempel. However, once the bacteria have been killed, molecules digest peptidoglycans and therefore dampen down the immune response. Regulating the immune response in this way is i...DOE JGI upgrades its Microbial Genome Analysis System
... of 687 bacteria, 41 archaea, 24 eukaryotes, 1,661 bacterial phages, and 402 plasmids not associated with a specific microbial genome sequencing project. Among these genomes, 2,558 are finished and 257 are draft genomes. IMG 2.2 contains 227 microbial genomes sequenced at JGI, consisting of 131 finished and 96......stein In this weeks Journal , Regan et al. used bacterial artificial chromosome (BAC) transgenes to visualize the expression pattern of two glutamate transporters in mice, glutamateaspartate transporter (GLAST) and glutamate transporter-1 (GLT-1). These two transporters are primarily expressed in astroglia ...