Neandertal femur suggests competition with hyenas and a shift in landscape use
...femur that a shift to greater mobility had already begun prior to the transition to the Upper Paleolithic, prior to any appearance of modern humans in Europe. In addition, the cave was a hyena den at about the same time that the humans lived in it, the authors say. Archeological evidence indicates that hum...Mosaic mouse technique offers a powerful new tool to study diseases and genetics
... of its potential commercial applications, Luo has begun the process of licensing MADM through Stanford University's Office of Technology Licensing. Meanwhile, he and his colleagues are returning to the lab to see if the technique can be applied to other aspects of developmental biology and disease in mice...Columbia dedicates new 300,000 sq. ft. Irving Cancer Research Center
...how cancer develops, but our discoveries have just begun to improve therapies for patients." "This new research facility will help assemble our cancer researchers under the visionary leadership of Dr. Dalla-Favera, fostering collaboration and the translation of new ideas from clinical observations to new t...Gene implicated in chronic kidney disease
...c kidney disease," Winn said. The researchers have begun a broader genomic screen of additional families from around the world to further examine genetic mechanisms in FSGS. Collaborators on the study include Merry Kay Farrington, April Hawkins, Nikki Daskalakis, Shu Ying Kwan, Seth Ebersviller, Margaret P...Hopeful results from interrupted Alzheimer's vaccine study
...enters in the United States and dosing has already begun at some sites. All the trials have been funded by Elan Corporation and Wyeth Pharmaceuticals. Results from the interrupted trial show that on the whole, study participants whose immune systems mounted a response against beta amyloid performed signif...Deeply held values fuel debate over offshore wind power
...d other faculty at the University of Delaware have begun offering an advanced graduate seminar, "Offshore Wind Power: Science, Engineering, and Policy," believed to be the first of its kind in the country. The scientists also have established a Web site on offshore wind power, with links to their recent re...Scientists journey to southern Africa to unravel the secret world of elephant communication
... O'Connell-Rodwell and other elephant experts have begun to explore the possibility that the Thai elephants...epartment of Otolaryngology, O'Connell-Rodwell has begun collaborating with department chair Robert Jackler; Sunil Puria, an associate professor (consulting)......iver nor bite. Recently, the researchers have also begun to collect samples from cyanobacteria, single-celled organisms that occur as slimy mats or filaments in places such as coral reefs and mangrove lagoons. Some of these compounds have biochemical activities that could be useful in medicine -- killing m...Single gene is genetic switch for fly sexual behavior
...e researchers. Dickson and colleagues have already begun collaborations with other researchers to determine how the fruitless gene might be involved in other behavioral patterns like aggression. "I think it is going to be fascinating to try to figure out how a fly decides between 'love' and 'war', and what...NHGRI selects 13 new targets for large-scale sequencing program
... genomes two times over. This sequencing strategy, begun last year on another set of mammals, is used primarily to identify features that are similar, or conserved, among the genomes of the human and other mammals. Sequences that have been conserved throughout evolution often reveal important functional re...Rodent social behavior encoded in junk DNA
...ic quest for the neural basis of familial behavior begun at the NIMH Intramural Research Program in the mid l980s by now NIMH director Thomas Insel, M.D. By l993, his team had discovered that the distribution of brain receptors that bind to the hormone vasopressin differed dramatically between monogamous a...MicroRNA tweaks protein that controls early heart development
...id the field of microRNA studies has only recently begun to blossom. One of the key challenges is to determine which messenger RNA any given microRNA will target. Hundreds of genes are known to produce microRNA, but in vertebrates there are only three or four known targets for those hundreds. "We are lear...Scientists devise way to measure RNA synthesis on the fly in a live cell
...at produce proteins. Some biologists have recently begun to identify families of RNA molecules that also play a major role in determining when and how genes are turned on and off, but they have lacked the ability to monitor action of these molecules as it happens within a single living cell. Now Cluzel an...Marshfield Clinic researchers launch study of environmental causes of Alzheimer's disease
...HFIELD, Wis. -- Marshfield Clinic researchers have begun searching for genetic and environmental links to Alzheimer's disease as a first step toward developing diagnostic markers to identify people at risk before they develop the disease. Researchers will study the DNA of Alzheimer's patients from its data...Experts to explore genetics, therapies for connective tissue diseases at Jefferson
...rks," he notes. In addition, many researchers have begun exploring the potential use of both gene therapy and stem cell-based therapies in treating such disorders. On Saturday, June 18, a special Matrix Biology Symposium will be held to honor renowned molecular biologist Darwin Prockop. M.D., Ph.D., profes...Breakthrough: Scientists create world's tiniest organic particles
... chemist said. New studies with mice have recently begun at the UNC School of Medicine, which DeSimone joined as professor of pharmacology. "The process starts off when we make a master template in a clean room at places like the Triangle National Lithography Center at N.C. State University," DeSimone said...Gene changes linked to deficient immune suppression in MS
...and spinal cord. But only recently have scientists begun recognizing the direct involvement of T-regs in suppressing pathogenic T-cells. "There has been no specific marker for them," Vandenbark said. For the Journal of Neuroscience Research study, researchers compared the blood of 19 healthy donors, inclu...Nerve protector could make for new stroke treatments
...damage. In recent years, medical scientists have begun to understand that tPA activates an entire family of enzymes, called matrix metalloproteinases, that normally regulate how cell structures are held together. Dr. Lipton, together with first author Dr. Zezong Gu, and other colleagues at Burnham, Unive...Forsyth scientists find three bacteria associated with oral cancer
...tic Indicator of Oral Cancer," reports on a study, begun in 2000, in which the scientists compared bacterial samples from the saliva of 229 healthy subjects with samples from 45 patients who had been diagnosed with oral cancer. The team found elevated levels of three bacterial species (C. gingivalis, P. me...A systematic search through human genes has begun at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Working within the MitoCheck consortium that includes 10 other institutes throughout Europe, the EMBL scientists will silence all human genes, one-by-one, to find those invol...