New finding points way to foiling anthrax's tricks
...c. 5 print edition. Many bacteria, including the benign Escherichia coli in our gut, make small molecules ...iderophore is a general strategy of bad as well as benign bacteria, according to the researchers. To date, however, only the pathogenic forms of E. coli and B...Blame myelin for many neuropsychiatric disorders
...r's) and nicotine patches. "Through these rather benign interventions," Bartzokis said, "such effects on the brain's vulnerable oligodendrocyte populations may offer exciting opportunities for the prevention of both developmental and degenerative brain disorders. They deserve much closer scrutiny."...Does natural selection drive the evolution of cancer?
...ea might be to develop new drugs that would act as benign cell boosters. Such drugs would specifically target the more benign cells in a tumor to increase their relative fitness over their malignant neighbors. This would allow...Exposure to dioxins influences male reproductive system, study of Vietnam veterans concludes
...ans exposed to dioxin had lower incidence rates of benign prostate hyperplasia (BPH), better known as enlarged-prostate disease. BPH is a disease in humans that is caused by an enlargement of the prostate. Patients must strain to pass urine and they also must urinate frequently. BPH can lead to complication...Other highlights in the November 15 JNCI
...th a decreased risk of breast cancer in women with benign breast disease, according to a new study. Lobular involution, part of normal aging, is the regression of the milk-producing glands or lobules in the breast. Lynn C. Hartmann, M.D., of the Mayo Clinic in Rochester, Minn., and colleagues examined the...Scientists design a PSA-activated protoxin that kills prostate cancer
...ll have developed a non-cancerous condition called benign prostatic hyperplasia (BPH) in which the prostate gland becomes enlarged. The findings reported today (Friday 10 November) have the potential to improve the survival and quality of life for men suffering from both these conditions. Sam Denmeade, a...Radiation increases risk of second primary tumors for childhood survivors
...loping both malignant brain tumors like glioma and benign tumors like meningiomas. The risk of a second tumor increased as the dose of radiation used to treat the first cancer increased. Children under age 5 were especially vulnerable to the development of secondary gliomas. The authors suggest that the inc...Viral marker of human migration suspect
A benign virus previously used as a marker in tracing human migration may be unreliable, according to researchers at Penn State. Results of this study also suggest that some viruses might be undergoing much higher rates of evolution than previously thought. ...Genomic comparison of lactic acid bacteria published
...ithout the contribution to our food supply of such benign microbial players as lactic acid-producing bacteria. Researchers from the U.S. Department of Energy Joint Genome Institute (DOE JGI) and the University of California, Davis, and their colleagues have characterized the genome sequences of nine differ...18th EORTC -- NCI -- AACR Symposium
...ith locally recurrent or advanced disease, or with benign prostatic hyperplasia phase I trial now under way Patients respond well to first study to test higher doses of an immunoconjugate anti-cancer drug; clinical trial reveals limited side effects and evidence that it can stabilise disease Apoptoti...Carnegie Mellon scientists use 'green' approach to transform plastics manufacturing
...m showed that you can steadily add environmentally benign "reducing" agents -- vitamin C, sugars or standard free radicals -- to chemically reduce CuII to CuI. This unprecedented approach continuously reduces CuII to CuI at the same rate CuII forms while retaining the desired balance between the two states....'Failed' experiment yields a biocontrol agent that doesn't trigger antibiotic resistance
...servation. A plasmid with one or the other of the benign mutations persisted, although it replicated a little more frequently than a mutation-free plasmid. How could it be, he wondered, that a bacteria with both mutations could not survive? The professor surmised that when the two mutations were brought t...Preventive ovary removal linked to early death in younger women
...unger than 45 years has cancer of the ovaries or a benign disease in the ovaries that requires removal, however, there is still compelling reason to remove the ovaries for treatment. Removal should also be considered in older women and in women with a very high risk of ovarian cancer, he says. In their stu...Reconstructed 1918 influenza virus induces immune response that fails to protect
...ucted 1918 influenza virus and a second group with benign human influenza. The mice infected with the 1918 v...sease and died. The animals infected with the more benign viruses did not develop an immune response that was as strong, and fewer of these animals died. Gene...Gene therapy study takes aim at prostate cancer
... the human form of the gene is normally present in benign prostate or low grade tumor but is lost as the tumors become more malignant."This characterized it as a tumor suppressor gene that is active in the prostate," said Kadmon. When the gene is introduced into the tumors of animals lacking RTVP-1, it su...New target for cancer therapy identified
...d. "What's more, telomerase is not associated with benign tumours; it's a marker for malignant tumours only. "If we can control the production of telomerase we can prevent the immortality of cancer cells and therefore cancer formation." Associate Professor Liu and his colleagues have been investigating br...Sensitive and specific biomarker for early detection of prostate cancer identified
...both cancerous and healthy tissue, particularly in benign prostate disease, resulting in significant numbers of false positive cases. The DRE, based on physician touch and skill, relies on subjective judgment. As a result, a man who has prostate cancer can have both a normal PSA and DRE. Conversely, an indi...Studies find general mechanism of cellular aging
...n't you like some evidence that these not entirely benign things were having a beneficial effect? Now we have a biomarker that can directly test the effects of such things," he said.......t, age at first live birth, the number of previous benign breast biopsy examinations, and the number of first-degree relatives with breast cancer. The researchers investigated whether information on breast density, which was available for 7,251 women in the BCDDP, could improve absolute breast cancer risk ...