Studies confirm celecoxib may help prevent colorectal cancer in high risk patients
...opy at three years. The incidence of one or more benign tumors during colonoscopy was 61 percent in those taking placebo; in patients taking celecoxib this percentage was reduced by 45 percent (p<0.0001). The relative risk of advanced neoplasms (tumor) with adenomas more than one centimeter in diamet...News tips from the Journal of Neuroscience
...etween axons and schwannoma cells. Schwannomas are benign tumors made up of abnormal Schwann cells that fail to myelinate peripheral axons and often bear a mutation in the neurofibromatosis type 2 (NF2) gene. NF2 normally suppresses signaling by Rho family GTPase that regulate actin cytoskeleton dynamics. R...New study confirms the ecological virtues of organic farming
...ls emitted larger quantities of an environmentally benign gas called dinitrogen (N2), than soils treated with conventional synthetic fertilizer. One explanation for this disparity is that the organic and integrated soils contained active concentrations of denitrifying bacteria--naturally occurring microbes ...Astronomer announces shortlist of stellar candidates for habitable worlds
...perature and metallicity of the Sun. It also has a benign companion star. HD 211415, about half the metal content of Sun and a bit cooler, this star is in just a little farther away than HD 10307. 18 Sco, a popular target for proposed planet searches. The star, in the constellation Scorpio, is almost an ...Scientists force viruses to evolve as better delivery vehicles for gene therapy
...esearcher has shown that viruses - in this case, a benign one - can be forced to evolve in ways to benefit humans. The adeno-associated virus, or AAV, is a common, though innocuous, resident of the body that has received a lot of attention in recent years as a possible carrier for genes in gene therapy. Bec...Pesticide combinations imperil frogs, probably contribute to amphibian decline
...ed susceptibility to meningitis caused by normally benign bacteria. Four years ago, Hayes showed that atrazine, the most common weed killer used on corn in the United States, disrupts the sexual development of frogs, feminizing males into hermaphrodites - frogs with female sex organs invading their testes -...Five European laboratories forms a concerted effort to understand tumor-host interactions
...ular and cellular interactions between the normal, benign cells of the tumor microenvironment, and the cancer cells. These interactions represent an attractive target for cancer therapy, because normal cells are genetically stable, and would not be expected to develop resistance to therapeutic agents," says...UW scientists unravel critical genetic puzzle for flu virus replication
...pment of new antiviral drugs and the harnessing of benign influenza viruses as gene vectors to optimize vaccine production, Kawaoka says. "We need to have more antivirals for influenza," according to Kawaoka, "and as these segments get incorporated into the particle as a set, it suggests these elements coul...Vitamin A analog is a potential lung cancer preventative with few side effects
...oses of bexarotene ended up with fewer and smaller benign and malignant tumors than mice that were not treat...r 12 weeks after the animals had already developed benign tumors following injection of a lung carcinogen. Bexarotene also inhibited the progression of benign...File compression can expand mammography's power
...the edges of medium-sized objects - which could be benign cysts with smooth edges, for example, or cancerous tumors with rough edges - up to large-scale patterns in tissue fiber. "The edges of tumors are where growth occurs, and they tell radiologists whether what they see is a tumor or not," Lucier said. "......, "we know that expression of ZBP1 correlates with benign tumors, while suppression of ZBP1 is associated with metastasis--when motile cancer cells break off from the primary tumor and invade other areas of the body. So a drug that could force tumor cells to express ZBP1 might prevent cancers from spreading...Model identifies genes that induce normal skin cells to become abnormal
...ironment of metastatic melanoma cells could induce benign skin cells to become cancer-like. The researchers seeded a particularly aggressive form of human metastatic melanoma cells onto a three-dimensional collagen matrix and allowed the cells to precondition the microenvironment for several days. The mal...The ethics of selecting for existence
...McMahon questions the difference between seemingly benign forms of selection and objectionable choices, pointing out that those who maintain it is no detriment to be disabled must also accept the implausible view that there is no basis for objection to deliberate inflictions of prenatal injury rendering a p...Study identifies several new bacterial species associated with common infection in women
... the causes of bacterial vaginosis (BV), a usually benign disease that is also linked to serious health problems including pelvic inflammatory disease, an increase in the viral load of HIV from infected women and a two-fold increase in risk for pre-term labor and delivery. Now researchers at the Fred Hutch...Alaska avian flu project issues initial surveillance results
...what genetic changes are important when a normally benign virus becomes a pathogen." The 1918 influenza virus which caused one of history's most deadly epidemics -- an estimated 50 million people died and almost half of those who died were healthy, young adults -- was identified in October 2005 as a bird fl...U-M scientists say fused genes trigger the development of prostate cancer
... analyzed, but found no evidence of gene fusion in benign prostate tissue or in prostate tissue with non-cancerous changes. "The data in our study provides tantalizing evidence that gene fusion is the causative agent - the initiating event - in prostate cancer," says Arul M. Chinnaiyan, M.D., Ph.D., the S....Cerebellum found to be important in cognition and behavior
... has made us aware that cerebellar injury is not a benign finding. We now know to look for it, and can counsel families that their children are likely to have deficits that extend beyond motor, and that may benefit from early intervention." A study presented mid-September, at the American Academy of Cerebr...U-M researchers identify new blood test for prostate cancer
...ently high PSA. A high PSA level can also indicate benign prostate conditions. "Initially, we envision this ...sy to better determine whether it's a cancerous or benign condition. In the future, I think this could replace PSA," says lead study author Arul Chinnaiyan, M...Story tips from the Department of Energy's Oak Ridge National Laboratory, September 2005
...rity for many years, while others may be in fairly benign locations or might be changed often. Oak Ridge National Laboratory researchers have developed Seal Selection Tool software that provides administrators access to seal performance data collected from stringent DOE-NNSA designed tests. The tool will he......ontrol (CDC). In most cases, it causes relatively benign fever, chills, and headaches that can be treated with antibiotics. However, when spread by aerosol, tularemia can cause severe respiratory illness and systemic infections and is associated with a 30-40 percent mortality rate. "We are going to learn ...