Tag: "benign" at biology news

Researchers discover why melanoma is so malignant

...at occasionally physicians discover that perfectly benign melanocytes will sometimes manage to migrate through a patient's body into, say, the lymph nodes. This phenomenon isn't related to cancer, but rather demonstrates the latent ability of melanocytes to travel Finally, the research team found that when ...

UCI receives $1.5 million National Science Foundation grant to research electronic waste

...a, which supports the design of new materials with benign environmental impacts and studies to maximize the efficient use of individual materials throughout their life cycles....

Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue

... the breast to near-infrared light," he says. This benign therapy could potentially eliminate months of debilitating chemotherapy and radiation treatment, he adds. "The laser we used is a 3-centimeter beam that's held like a flashlight," he notes. "We can take the beam and put anywhere we want. We can shine...

Building a better mouse model of lung cancer: FHIT counts

... the protein. While the normal mice developed only benign tumors, 17 percent of the mice that had lost one copy of the gene developed malignant tumors and all of the tumors in the mice that lost both copies of the gene were malignant. "This suggests that even very low levels of the protein might be enough ...

Immune system's distress signal tells bacteria when to strike back

...h, activate genes that quickly transform them from benign passengers in the bowel into deadly blood-stream invaders. "Most of the time these microbes are content to live and grow in our intestines," said John Alverdy, M.D., professor of surgery at the University of Chicago and director of the study. "They ...

Enlisting genomics to understand flu evolution

...mples from around the world," he adds, to find the benign virus strain that will become next season's scourge. The more genomes scientists collect--and the more refined the tools of genomics become--the greater the chances of developing more effective vaccines....

PTEN, TSC2, and tumorigenesis

...rvard School of Public Health) found that the more benign nature of tumors lacking Tsc2 arises from the fact that a negative feedback loop exists to limit Akt signaling in these tumors. However, the loss of even one copy of Pten is sufficient to overcome this feedback mechanism, reactivate Akt, and dramatic...

The very defensive caterpillar

...eins appear to be able to persist from the initial benign E. coli infection and then confer resistance against the second, usually lethal, infection by the pathogen. Using RNAi techniques workers at the University of Bath have shown that several different proteins can confer this protective effect against ...

Forsyth scientists find three bacteria associated with oral cancer

...y stages, oral cancer may be asymptomatic or mimic benign conditions, so those who have it do not seek dental or medical care. "A saliva test would be an easy, non-invasive way to diagnose or monitor patients." Until such a test exists, Mager added, "I cannot overemphasize how important it is for every adul...

Controlling wildlife trade key to preventing health crises, study says

...ch animal traded. The pathogens, and even commonly benign microbes these animals carry are sometimes transmitted to other species, including humans, in the process. Domestic animals and wild scavengers in market places and villages also consume the waste and remnants of infected trade animals providing fur...

Costly breeding programs for endangered species pay off

...d to select only the most fit lines while the more benign environment allowed low-fitness lines to persist in captivity," said Meffert. Though the findings clearly support the case for expensive MAI breeding schemes for some endangered animals, Meffert suspects that might not be the case for species that re...

Enzyme family plays role in Alzheimer's: University of Toronto study

... gamma-secretase could be separated from its other benign activities. "This finding provides hope that Alzheimer's treatments can be developed that reduces toxic activity of certain gamma-secretases while still maintaining the beneficial activities of other family members," says Peter Mastrangelo, a researc...

Silenced gene suggests greater risk, possible marker for African-Americans with prostate cancer

...can, and 38 Caucasian-American) from patients with benign prostate hypertrophy, or enlarged prostate. All Asian samples were obtained from Shimane University Hospital in Izumo, Japan; all Caucasian and African-American samples were obtained at SFVAMC. From each sample, the researchers took DNA, amplified it...

Other highlights in the June 15 JNCI

...enetic disease characterized by the development of benign lesions in hair follicles and pulmonary cysts, may be a tumor suppressor gene that predisposes a person to renal tumors when both copies of the gene are inactivated. BHD syndrome is caused by a mutation in at least one copy of the BHD gene. People wi...

Engineered skin offers clues to melanoma development

...id not receive hTERT remained in an early stage of benign growth. Finally, the team looked at the PI3K and Raf pathways, frequently implicated in the development of melanoma. They found the expression of active PI3K, together with CDK4, hTERT, and inhibition of p53, produced invasive melanoma growth indisti...

Discovery offers promising lead in prostate cancer diagnosis

...ected prostate epithelial cells from malignant and benign prostate tissues and GeneChips, researchers identified ERG as the first proto-oncogene that is commonly overexpressed in early-phase prostate cancer. The cancer-causing genes known as oncogenes and tumor suppressor genes have long been known to be m...

Non-dieters more successful at boosting health than dieters, study finds

... the premise that obesity itself may be relatively benign compared with health habits, nutritionists and health professionals began to look for a more effective way of dealing with the health risks. One model that has arisen is known as Health at Every Size. Rather than focusing on calorie counting, this ap...

Harmful chemicals may reprogram gene response to estrogen

... made them more susceptible to uterine leiomyomas, benign tumors that are common in women over 30 years of age. These rats were then treated with DES during days 3, 4 and 5 of life, during a critical period of uterine development. Once the rats reached adulthood, almost 95 percent had developed the uterine ...

Function of cancer genes discovered

...genetic condition cylindromatosis develop a lot of benign tumours on the skin. These tumours mainly occur on the head where they can cause serious malformations. People with this disease have a mutated form of the protein CYLD. Nijman and his colleagues used genetic screens to discover the molecular mechan...

NJIT plastics expert who develops safer explosives for soldiers gets honor

...terial Gogos is developing will be environmentally benign and more energy efficient than current similar materials used in different applications. Even better, these new materials will reduce waste and be inherently safer for anyone to handle. One use of the new material will be as an explosive because it...

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