Experimental drug prevents vaginal simian HIV transmission in monkeys Science study says
...es. The required drug dosage, for example, must be better understood and reduced. Also, the authors did not test if the drug protects against transmission of SHIV contained within infected donor cells, a mechanism of uncertain importance in HIV acquisition. Despite the challenges ahead, the authors say thei...Muscling in on a deadly cancer
...tect it early or develop new treatments based on a better understanding of the biology of the tumor," says C...h toward new therapies" less toxic to patients and better aimed at the cancer. Keller and Capecchi believe it still will take 10 to 20 years for new trea...Mechanism discovered for muscle wasting seen in diabetes, AIDS and other diseases
...om loosing muscle mass, and the MISR mice had much better survival rates than did normal mice with cancer. Thus, selective NF-kB blockade in muscle decreased muscle wasting and prolonged survival in this mouse model of cancer. "The discovery that NF-kB activation is sufficient to cause skeletal muscl......s a new target and a new set of ideas for pursuing better treatment." Akil notes that the brains of bipolar people in the study did not show the decreased FGF gene activity. "This was all the more remarkable since both groups of individuals were severely depressed at the time of death," she says. "This is ...Amphibians in dramatic decline; Up to 122 extinct since 1980
...ng new protected areas, captive breeding programs, better community engagement and protection of freshwater systems would enhance amphibians' chances of survival. "Since most amphibians depend on freshwater and feel the effects of pollution before many other forms of life, including humans, their rapid ...How to use math and a CT scanner to see how trees intercept light
...a), will tell you that many natural systems can be better understood using equations and models, provided ap... to a more complete and accurate model providing a better understanding of why some plants perform better in given light environments. This is important becau...The CF Foundation urges all states to include newborn screening for cystic fibrosis in test panels
...o are diagnosed at birth gain more weight and have better nutrition than those who are diagnosed later in li...linked to improved height and weight measurements, better pulmonary status, and cognitive benefits. "It is imperative that states add newborn screening for C...Purdue chemists give an old laboratory 'bloodhound' a sharper nose
...he lab and on the street, Gologan cautioned that a better understanding of its functioning was still needed. "One potential criticism of the device is that we haven't yet done an in-depth analysis of the mechanism," he said. "We think we know how it works, but haven't yet proven it. That's one of o...Biological importance of basal activity of appetite suppressor
...a low, sustained level of MC4R activation may be a better therapeutic agent for combating obesity than a more powerful activating molecule, which can result in the MC4R receptor becoming desensitized....Scientists identify new cause of obesity
...that has so far proved difficult to carry out -- a better approach may be a drug that assures the sustained, low-level MC4R activity that the researchers showed is essential for the protein to regulate appetite. "These findings provide a whole new way of thinking about how hormone receptors could cause dise...Multi-species herbivore outbreak follows El Nio drought in Panama
...ttention to these harbingers of climate change. A better understanding of the deep natural history of these systems may help us to predict outbreaks involving crop pests or human disease vectors."...Biomedical engineers at case develop first sliver-sized sensor to monitor glucose levels
... current. "We also thought that color can be seen better from the outside if the sliver is not too deep, and if it gets distorted by the skin this can be corrected by using a white spot inside the sensor that does not change color," Gratzl said. The sensor, which is one to two millimeters long and 100 to ...Zebrafish may offer researchers powerful new tool for studying innate immunity
... of zebrafish an achievement that could lead to a better understanding of infectious diseases and certain c...unity. They hope to use the zebrafish as a tool to better understand how innate immunity may ignite adaptive immune response and to investigate potential ther...Hormone therapy's effect on breast density is not the same for all women, Group Health study finds
...sensitivity of mammograms," said Aiello. "Having a better understanding of that link and how it relates to v...isk factors may help women and their physicians to better evaluate whether HT is the right choice for them." Aiello's study is the largest population-base......hat goes wrong in our joints as we age and to find better treatments for arthritis. Embryologists have already discovered quite a bit about the earliest stages of joint formation. It is known, for example, that stripes of cells that form between developing bones subsequently develop into the permanent carti...Dr. Harris receives NIH Javits Neuroscience Investigator Award
...nges in synapses that likely will not only help us better understand how we learn and remember but also pave the way for better treatments of diseases that disrupt these processes. Her latest grant helps take critical forward st...Gene-altered mouse is model for rare autoimmune syndrome
...d animal models lacking the gene we would not only better understand its role in immune development, but see disease characteristics as well," said Zhuang. "We had no prior knowledge that we would produce such a precise model of Sjgren's syndrome." Indeed, he said, the mice lacking the gene had all...Leading scientists to discuss research applications for therapeutic cloning
... research will revolutionize medicine by providing better treatments for disorders such as Parkinson's disease, amyotrophic lateral sclerosis (ALS), Alzheimer's disease, heart disease, stroke, diabetes, spinal cord injuries and genetic diseases. While the hopes are real, scientific findings remain ambiguous...Genetically modified parasite lets researchers probe immune system's memory
...efforts to develop other vaccines. "We are so much better at understanding how the immune system responds th...," Beverley notes. "These new results may help us better direct the immune response toward long-term vaccination."...UC Riverside professor organizes a workshop on vitamin D and cancer treatment and prevention
...ay." Norman's laboratory is currently involved in better understanding the molecular mechanisms of how Hormone D generates biological responses. A distinguished professor of biochemistry and biomedical sciences at UCR, Prof. Norman has served as one of three principal organizers of the Vitamin D Workshop,...