Gene for Joubert syndrom with excessive brain folds discovered by UCSD researchers and Harvard team
...ildren. "These populations allowed us to better exploit the work of the human genome project to arrive at the chromosomal hot-spot," he said. Noting that many children with Joubert Syndrome also have autism, Gleeson explained that "if we can understand how the AHI1 gene works and how its dysfuncti...International human genome sequencing consortium describes finished human genome sequence
...lability of genome sequences from other organisms, better computational models and other improved resources." The Nature paper also provides the scientific community with a peer-reviewed description of the finishing process, and an assessment of the quality of the finished human genome sequence, which wa...Babies born after surgery on eggs
...to happen," Cohen says. "Then they would have much better ground to stand on."...For inferring the biological tree of life, simple is better
...k assessment. Here again, simpler would lead to a better outcome."...OHSU study: Bacterial switching mechanism key to survival
...crystallography helps all biomedical scientists to better understand its function. "Our major focus is to determine structures of proteins and their biologically relevant complexes so we can understand the biology more completely," he said. "My lab focuses on bacterial systems. If you can understand the fun...New DNA repair enzyme makes mistakes to save lives of cells
...or filling gaps during DNA replication. Now with a better understanding of how its role is to permit replication to proceed, the authors note in the current study that POL-Q's behavior is more consistent with the Y family of polymerases that bypass damage. Indeed, comparisons of its protein sequence to othe...New genomic method can identify disease-causing genes
...tional technique. The studies are directed toward better understanding the genetic causes of a range of human diseases and toward pharmacogenetic analysis of how various drugs that are used commonly to treat disease work in humans. The paper, entitled "In Silico Genetics: Identification of a Novel Func...Single genetic defect links many risk factors for heart disease and stroke
...e don't know the mechanism that links the two." A better understanding of this mechanism could yield new treatments, said Lifton. He speculated that the genetic defect might produce clinical pathologies by crippling the energy-production capability of the mitochondria. Alternately, it might increase the pr...NIH funds new bioinformatics resources at UT Southwestern
...dies using cultured cells, allowing researchers to better identify altered genes and proteins that lead to d...to the development of disease. From this, they can better devise drugs or treatment options for type I diabetes, multiple sclerosis, systemic lupus erythemato...Genetics play role in response to most common asthma drug
...sthma more than others. The findings could lead to better ways to individualize asthma therapy based on pati...ns. "If we can pinpoint which individuals will do better with a certain type of therapy, we can improve their lives more quickly and save them -- and the hea...Three years of Proba, the 'smart' satellite that runs itself
...uring the last three years has made it possible to better model the radiation environment around Earth. Another instrument in its payload is the Debris In-orbit Evaluator (DEBIE) which monitors tiny micrometeoroids or space debris between a centimeter to under a millimetre in diameter. About Proba Prob...Latest buzz in research: Intoxicated honey bees may clue scientists into drunken human behavior
...MBUS, Ohio Inebriated bees could give researchers better insight into alcohol's effects on human behavior, ...sumption affects social behavior as well as gain a better understanding of the basic mechanisms that drive alcohol addiction and tolerance. "Honey bees are ve...Pesticides may promote Parkinson's disease and exercise may offer protection
...rch into Parkinson's disease is helping scientists better understand some of the mechanisms of this serious and disabling brain disorder, which affects about 1 million people in the United States. Knowledge of the environmental factors and genetics of this illness has allowed investigators to create models ...Soaking up signal: Endocytosis controls spreading and effective signaling range of Fgf8 protein
...a field of target cells are unknown. In seeking to better understand how this signaling is controlled, researchers Steffen Scholpp and Michael Brand of the University of Technology, Dresden and the Max Planck Institute-CBG, Dresden, have investigated the role of Fgf8 in the development of nascent neuroectod...New center to map DNA of key lab mice
... genetically distinct mice, researchers can gain a better understanding of the relationship between genes and the environment in the development of disease in humans. Almost 200 human diseases are affected by exposure to environmental substances. For most diseases, more than one gene is involved and researc...Medical informatics project targets ovarian, breast cancers
...ve-year, $8 million project that will help doctors better understand the damage caused by breast and ovarian...rts. "In the end, we believe our work will lead to better therapies for ovarian and breast cancer patients." The researchers will study the genetic and molecu...Biodiversity: measuring up to the loss
...s show coarser temporal resolution, they have much better geographic representation; they're based on nearly all species in a group worldwide rather than on a potentially biased subset. The Red List Index therefore provides a reliable baseline to track progress toward the 2010 target, not only for birds but...GENEPI: a tool to refine and fine-tune radiotherapy treatment for cancer
...e effective, treatment for those predicted to have better tolerance". The GENEPI (GENEtic pathways for the Prediction of the effects of Irradiation) project aims to provide a scientifically rigorous method of predicting both radiotherapy efficacy and side effects based on a wide range of genetic, physical ...Yerkes researchers to present array of new data at Society for Neuroscience Meeting
...ship between the hypothalamus and CART in order to better understand and ultimately control appetite and addiction. (6 p.m. 7 p.m.) October 26, 2004 Each study is embargoed until the date and time of presentation. Poster Presentations Dr. Kuhar and his research team: showed early life e...Solutions to stop fishermen returning dead and dying marine animals back into sea - study
...es must be generated by alternate means. "Granting better access to fishing grounds or allowing more fishing time to those who fish more selectively are methods that have proved successful. Once these incentives are created, fishermen's knowledge should be used to develop acceptable fishing techniques and ...