Tag: "blindness" at biology news
deCODE discovers cause of major subtype of glaucoma
... Glaucoma is one of the most common causes of blindness
worldwide. There are various types of glaucoma, all of which lead to damage in the optic nerve and progressive loss of vision. Exfoliation glaucoma is caused by the buildup of fibrous deposits on the surfaces on the front of the eye. Between 10-20% o...
Link identified between Alzheimer's disease and glaucoma
...cated in glaucoma, the major cause of irreversible blindness
worldwide. Research carried out at the UCL Institute of Ophthalmology and funded by the Wellcome Trust has also shown that novel drugs being trialled for Alzheimer's disease which target this protein may be used to treat glaucoma. The research team...
Research team enlightens the reasons for severe blindness
...sease is caused by a single mutation. LCA causes blindness
very early on often shortly after or within a few...stricted functionalities of cilium cause deafness, blindness
or even severe syndrome diseases. LCA is therefore a good model which also enables to gain more know...
Fish eyes could hold clue to repairing damaged retinas in humans
...s are responsible for three quarters of registered blindness
in the UK(1). Researchers at the UCL Institute of Ophthalmology and Moorfields Eye Hospital have studied these Mller glial cells in the eyes of people from 18 months to 91 years of age. In research funded by the Wellcome Trust, the Medical Researc...
Study identifies new gene therapy tools for inherited blindness
...s toward filling a gap in the toolkit for treating blindness
by identifying DNA elements that control when and where genes linked to blindness
are turned on. "In its most basic form, gene therapy requires three components," explains Joseph Co...
Gene variant increases risk of blindness
...al loss in older people and the commonest cause of blindness
in the USA and European countries. The researchers based their findings on studies of patients with AMD (603 from England and 244 from Scotland) who were compared with 701 unaffected people. They found that a variant in the complement C3 gene i...
Penn researchers report that gene therapy awakens the brain despite blindness from birth
...enced, Aguirre said. The traditional view is that blindness
in infancy permanently alters the structure and fu...retinoid-visual cycle. The same mutation causes a blindness
in humans called Leber congenital amaurosis, or LCA. It is the first human eye-retinal disorder sla...
JCI table of contents: June 21, 2007
...ucoma Glaucoma, a leading cause of irreversible blindness
in the United States, usually occurs when increased fluid pressure in the eye damages the optic nerve. However, in a significant subset of glaucomas elevated intraocular pressure (IOP) is not a symptom [e.g. in normal tension glaucoma (NTG)] and in o...
UCF nanoparticle offers promise for treating glaucoma
...r treating glaucoma, an eye disease that can cause blindness
and affects millions of people worldwide. The nanoparticle can safely get past the blood-brain barrier making it an effective non-toxic tool for drug delivery, said Sudipta Seal, an engineering professor with appointments in UCFs Advanced Materials...
'Lucky 13' as new gene discovery offers further hope for childhood blindness
..., causes one of the most common forms of inherited blindness
in babies. Scientists at the University of Leeds, ... to carry a mutation in the LCA5 gene, the risk of blindness
in their children and grandchildren is still virtually zero as long as the other parent does not car...
Discovery in orange cauliflower may lead to more nutritious crops
...romised immune systems and is the leading cause of blindness
in children. "A large percentage of the human population depends on staple crops for nutrition," said Li, an adjunct assistant professor in the Department of Plant Breeding and Genetics and a scientist at the U.S. Department of Agriculture -- Agricul...
UF researchers awaken vision cells in blind mice
...s experimented with mice with a form of hereditary blindness
called achromatopsia, which affects about 1 in 30,...tina. The disease results in nearly complete color blindness
and extremely poor central vision. Within two months of the gene therapy injection into the subret...
Media events planned for 2007 American Society of Gene Therapy meeting, May 30-June 3
...cer, arthritis, infectious diseases, and childhood blindness
will discuss their research and progress toward bringing these promising gene therapy technologies and products to the clinic. Speakers include: Theodore Friedmann, M.D Philip J. Mease, M.D. John Rossi, Ph.D. Joseph C. G...
Landmark study highlights complex genetic risk factors behind type 2 diabetes
...ajor cause of heart disease and stroke, as well as blindness
and kidney failure. There are currently around 200 million people who have type 2 diabetes worldwide, yet its underlying cause is poorly understood, limiting both treatment and prevention. Lifestyle factors, such as poor diet and lack of exercise h...
Researchers making significant strides against diabetic retinopathy
...type 2 diabetes and is the leading cause of adult blindness
in Americans the outstanding research being done in this area will have a significant impact on the millions of people with diabetes."...
Research project tackles 'regeneration' gap
... ago as well as scientists who are trying to treat blindness
by influencing the activity of stem cells in the human eye. In terms of brain diseases, scientists may look at ways to mobilize and reinforce the bodys own supply of adult stem cells to protect against or fight Alzheimers and Parkinsons diseases, can...
Fruit fly gene research may shed light on human disease processes
...he same numbers as men from such ailments as color blindness
or hemophilia, since their double dose of X genetic material helps compensate for 'defective' genes on one of their chromosomes. Men, with just one X chromosome, have less protection. Understanding the role of the X chromosome and the mechanism of ...
Genetic studies endow mice with new color vision
... similar to what some people with red-green color blindness
see scientists have now transformed their vision by introducing a single human gene into a mouse chromosome. The human gene codes for a light sensor that mice do not normally possess, and its insertion allowed the mice to distinguish colors as never...
Laying sleeping sickness to rest
...nd can lead to skin lesions, tissue damage, fever, blindness
and death. Chagas disease affects 16-18 million people across the Americas, and can cause intestinal complications, neurological disorders, heart damage and death. Although drugs are available to treat these diseases, their use is hampered by toxicit...
Transport interrupted -- Texas A&M biologists trace cause of early blindness to tissue defect
...editary retinal degenerative disease that leads to blindness
in an estimated one in every 100,000 people, beginning with severe loss of vision and night blindness
as early as the pre-teen years and progressing to complete blindness
by middle age. Using a line o...
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