Tag: "blockers" at biology news

Cell receptor may lead to new 'biomarker' for pancreatic cancer

...preclinical research is needed before RON receptor blockers become available for human testing....

Weill Cornell pharmacologist receives prestigious NIH MERIT Award

...els in patients. These include use of NO synthesis blockers to reverse hypotension (1989) and increase responsiveness to pressor drugs (1991, 1994); novel approaches to limit the availability of substrates for NO synthesis (1994, 1995, 1996); blocking the synthesis (1999, 2000, 2001) and use (1996) of tetrahy...

8 plants from South Africa may hold potential for treating high blood pressure

...zyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB). These drugs not only lower blood pressure but offer additional protection to the brain and heart. ACEI, in particular, provide beneficial properties to patients with type 1 diabetes. In an effort to identify indigenous plants consumed by the...

Different approach needed to protect brains of premature infants

...n. "In the three-day-old mouse brain slices, the blockers couldn't prevent damage to the axons," Goldberg says. "So something other than glutamate is killing the axons at that point in brain development." In the early brain, axons lack a protective sheath called myelin. Glial cells supply this sheath, whi...

Targeting the adrenal gland could be key strategy against heart failure, Jefferson scientists show

...a bad situation worse. The typical treatment beta blockers inhibit the beta adrenergic receptors on the heart, blocking the hormones that force the heart to work overtime. Dr. Kochs group focused instead on the source of catecholamines the adrenal gland. It discovered that in heart failure, the extra ho...

JCI table of contents: January 2, 2007

...failure drugs The group of drugs known as beta blockers help slow nerve impulses traveling through the hea... receptors present in cardiac cells. As such, beta blockers have become a mainstay of the treatment regimen for chronic heart failure. However, doctors have rem...

Genetic mutation alters response to heart failure drugs

The group of drugs known as beta blockers help slow nerve impulses traveling through the hea... receptors present in cardiac cells. As such, beta blockers have become a mainstay of the treatment regimen for chronic heart failure. However, doctors have rem...

Tarantula venom and chili peppers target same pain sensor

...hey give us clues as to how specific activators or blockers on these channels can be designed to treat persistent pain from arthritis, bladder infections, or other diseases." The researchers determined the venom peptides' effect in neuron cell cultures, measuring the tell-tale rush of calcium ions when the v...

Data show treatment with Remicade reduced hospitalizations for ulcerative colitis patients by half

...lled lymphoma in patients on REMICADE or other TNF blockers are rare but occur more often than expected for people in general. People who have been treated for rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, or plaque psoriasis for a long time, particularly those with highl...

Histamine tied to changes in blood pressure during exercise-recovery period

...e ages of 19 and 34. The group given the histamine blockers consumed them with water 60 minutes before beginning the exercise regimen. The studies in Halliwill's Exercise and Environmental Physiology Laboratories were designed to pursue the mechanisms involved in the exercise recovery period. The findings t...

Researchers devise new tools to help pinpoint treatments for heart failure

...ing PKA activity and lowering cardiac output. Beta blockers are now taken daily by about 5 million U.S. patien...cardiovascular diseases. The effectiveness of beta blockers has highlighted the need to better understand the system of biochemical signaling within heart cells...

Meth promotes spread of virus in HIV-infected users

...HIV attachment receptors, use of dopamine receptor blockers during HIV infection in meth users could be beneficial therapeutically to reduce HIV infection in these high-risk populations," Nair said. ...

Preclinical study shows chronic stress agitates ovarian cancer; reducing stress slows tumor growth

...ffect of stress on tumor growth," says Sood. "Beta blockers have been shown to be protective against cardiac d...erventions to reduce stress, as well as using beta blockers in cancer patients."...

Polycystic kidney disease: MRI provides an early alert to progression

...control and ACE-inhibitors or angiotensin receptor blockers (ARBs) can prevent progression of PKD. CRISP clinical centers are at the University of Kansas Medical Center in Kansas City, Emory University in Atlanta, Mayo Clinic in Rochester, Minn., and the University of Alabama at Birmingham. Washington Uni...

Inflammation and drugs to control this activity studied in a variety of tumors sites

...imal studies have shown a profound effect by COX-2 blockers against a variety of cancers," he said. Harris sai...r's disease. He hopes to continue to look at COX-2 blockers at sub-therapeutic doses in chemoprevention. "We need to look at a broader spectrum of conditions re...

Researchers reverse juvenile diabetes in animal model; Clinical trial FDA approved

...ers then combine the dendritic cells with specific blockers of molecules, known as CD40, CD80 and CD86, all of which can be synthesized in a laboratory. This treatment strategy was found to inhibit the interaction and destructive effect of T cells on the insulin-producing beta cells of the pancreas, a process...

Frog peptides block HIV in lab study

...gy that compounds secreted by frog skin are potent blockers of HIV infection. The findings could lead to topi... peptides as anti-microbial agents, including HIV blockers Frogs around the world are in trouble. And as species are lost, so are their biological treasures....

UC Davis researchers discover receptor pathway for C-reactive protein and its effects

...ity, high blood pressure with angiotensin receptor blockers and diabetes with thiazolidinediones and metformin are also shown to reduce the levels of CRP....

Nicotine triggers the same brain reward circuitry as opiates

...r findings suggest more effective ways that opiate blockers could be used to help smokers quit. In their exper...ers noted that clinical studies of opioid receptor blockers to relieve cigarette cravings "so far have produced mixed results, ranging from ineffectiveness at s...

JCI table of contents June 1, 2005

...rtin-4-receptor and mice treated with melanocortin blockers resist the cachexic effects of uremia on weight gain, body composition and metabolic rate. Therefore, kidney disease cachexia is caused by defective brain regulation of appetite. These observations may lead to novel therapies for the cachexia syndr...

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(Date:7/24/2014)... Some sticky research out of York University shows ... species of toxic grass fungus: moose saliva (yes moose ... Letters , "Ungulate saliva inhibits a grassendophyte mutualism" shows ... fescue grass (which hosts a fungus called epichlo festucae ... growth and less toxicity. , "Plants have evolved defense ...
(Date:7/24/2014)... O.D., a low vision specialist at The University of ... has been awarded a grant to help Harris County ... medication or surgery. , Even with corrective lenses, many ... However, there are a variety of low vision devices, ... offset their vision loss. , Iyer is using the ...
(Date:7/24/2014)... fire hazard in the United States, wildland managers often ... and suppressed trees (ladder fuels). These cuttings and ... low fire danger in order to dispose of the ... pollutants, managers often cover all or part of the ... as agricultural plastic, in order to keep water out. ...
Breaking Biology News(10 mins):Moose drool inhibits growth of toxic fungus: York U research 2UTHealth Dr. Bhavani Iyer awarded low vision grant 2Study gives new perspective on agricultural plastic, debris burning, and air quality 2
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