Uncovering the molecular basis of obesity
...a lower concentration of feeding hormones in their brain than normal mice. Being conserved across species B...he scientists suggest Bsx is also needed to enable brain cells to sense and respond to specific hunger signals from the body without it the mice do not feel...American Chemical Society's Weekly PressPac -- May 30, 2007
...he BBB poses daunting challenges to developing new brain medications Journalists' Resources: "Huh, a...he BBB poses daunting challenges to developing new brain medications Chemical & Engineering News When considering perceived obstacles to coveted achievem...What causes Alzheimer's? Researchers tie beta-amyloids to brain dysfunction
...D.C.Researchers tied the accumulation of the toxic brain protein beta-amyloid to Alzheimer's disease, accor...findings show that beta-amyloid is associated with brain dysfunctioneven in apparently normal elderly individualsproviding further evidence that it is likely...Hypothyroidism clearly linked to mood swings
...ression lethargy. Researchers, studying underlying brain processes in search of "why" this happens, reporte...al metabolic changes in the thalamusan area of the brain that helps process information from the senses and transmit it to other parts of the brain" she said......porns and Christopher Honey find the 98 percent of brain activity that other researchers consider just back...patterns. Sporns and Honey's work on modeling this brain activity sheds new light on how and when these mysterious fluctuations occur and offers insights int...Depiction of findings selected as '2007 Image of the Year' by Society for Nuclear Medicine
..., NY An image depicting research findings linking brain chemistry with aggressive personality has been nam...that healthy men with lower levels of a particular brain enzyme exhibited more aggressive personality traits, as measured by a standard personality questionn...A first: Simultaneous PET/MR images of the brain debut, increase molecular imaging capabilities
...ous data acquisition. The PET/MR data of the human brain revealed image qualities comparable to stand-alone...stage Alzheimer's, but it cannot determine reduced brain volume caused by atrophy. "By combining MR and PET, clinicians may be able to make a more sound dete...Michael R. Zalutsky receives SNM's 2007 Paul C. Aebersold Award
...that defined the feasibility of treating malignant brain tumors with labeled monoclonal antibodies; for contributing to the field of targeted radiotherapeutics, particularly those labeled with the alpha-particle emitter astatine-211; and for making significant advances in other aspects of alpha particle ra...SNM recognizes R. Edward Coleman with 2007 Georg Charles de Hevesy Nuclear Pioneer Award
...f PET scanning in lung cancer, prostate cancer and brain tumors. He was the nuclear medicine physician invo...ndocrine tumors, the metabolic characterization of brain tumorsbefore and after therapyand development of new methods for characterizing neuroendocrine tumor...Every moment counts: Predicting treatment responses earlier for brain tumor patients
....C.Using metabolic or molecular imaging to measure brain tumor patients' response to treatment is a powerfu... "Our study opens the door to the possibility that brain tumor patients may live longer and respond better to drug treatments," said Wei Chen, assistant prof...New insights into the neural basis of anxiety
...ssenger serotonin and a neural circuit involving a brain region called the hippocampus play crucial roles i...fic receptor molecule for serotonin, a signal many brain cells use to communicate. Mice that lack the serotonin receptor 1A have problems processing ambiguou...JCI table of contents -- June 1, 2007
...s, made up of the peptide amyloid beta (Abeta), in brain tissue. The role, if any, of inflammation in AD re...f some proinflammatory proteins are elevated in AD brain tissue, whether these proteins have negative or positive effects is still unclear. In the June 1 iss...Math that powers spam filters used to understand how brain learns to move our muscles
...ates of human muscle movements to explain how the brain draws on both what it recently learned and what it...olleagues built the new model, says the artificial brain in the computer, like its natural counterpart, is guided in part by a special kind of statistical pr...Gene therapy offers new hope for treatment of peripheral neuropathy
...rs continue to send signals to pain centers in the brain even after the surrounding tissue has healed. Unfo...ce of nerve cells in the spinal cord and the lower brain but not in the nerves in the limbs, to the paws of rats. A group of control rats received only the H...When the villain becomes your friend: The strange tale of muscle lactate
... serves to forward the activating signals from the brain to the muscle fibres where contraction takes place. They showed that in combination, lactic acid and adrenalin serve to help working muscles ward off the effects of potassium ions which leak from the inside to the outside of working muscle cells and ...An 'elegant' idea proves its worth 25 years later
...us and in the case of urea cycle disorders, causes brain damage, retardation, coma and even death. Despit... the hyperammonemia lasts, the higher the risk for brain damage." "This is a happy story," says Brusilow. "It isnt too often in genetic medicine that we ca...Yin and yang -- Balance could play key role in progression of Alzheimer's disease
...tides are produced in the correct proportions, the brain is healthy; but when that delicate balance is changed, pathological changes will occur in the brain and the persons memories become hazy, leading to eventual dementia." Wang expects that this imbal...Natural compound and exercise boost memory in mice
...ts, suggesting that it may be possible to optimize brain function by combining exercise and dietary supplem...tional changes in the dentate gyrus, a part of the brain involved in the formation of learning and memory. The findings, published in the May 30 issue of Th...Common treatment for methamphetamine overdose may damage brain cells
...ine overdose damages nerve cells in an area of the brain known to regulate movement, a new study shows. T...overdose in humans might worsen drug abuse-related brain injuries," says William Carlezon, PhD, at Harvard's McLean Hospital, who was not affiliated with the...Growth factors and environment combine to increase brain maturation
...th factors and the environment combine to increase brain maturation appears in the May 30th issue of the on...nship between these molecules in the modulation of brain plasticity....