US researchers show cottonseed drug is cancer treatment booster
...failed, only to become the world's most successful breast cancer drug. Will gossypol follow in the footsteps of tamoxifen? "There is a lot of research still to do, but we certainly hope so," said Dr. Xu. "The natural form of gossypol has been extensively tested in humans and is well tolerated for long-term ...32 new grants made for innovative technology R&D
...and Therapy of Breast CancerDevelop a new class of breast cancer diagnostic and therapeutic antibodies unique in their ability to recognize tumor proteins presented by the body's natural antigen display systems known as HLA. Revivicor, Inc. (Blacksburg, Va.) Production of Fully Human Polyclonal Antib...NIH awards Emory and Georgia Tech $10 million for partnerships in cancer nanotechnology
...ad applications to many types of tumors, including breast and colorectal cancer and lymphoma. Dr. Shuming Nie, PhD, principal investigator of the project, is one of the first scientists in the world to utilize nanotechnology in the biomedical field. Used in manufacturing for many years, nanotechnology en...Researchers find chemosignal that encourages women's sexual desire
...avoid transmitting odors such as curry through the breast milk. The breastfeeding women wore pads in their n...nto two groups, one group exposed to the pads with breast feeding substances, and the other group exposed to pads with potassium phosphate, a substance that m...Obese women with early-stage breast cancer more likely to die than women of normal weight
...are obese when they are diagnosed with early-stage breast cancer are at a greater risk of dying of their dis...verweight and normal-weight women with early-stage breast cancer treated with conservation surgery (lumpectomy) and radiation therapy. "We have demonstrated...Study describes basic mechanism in cell growth control involving damaged DNA
...ations that the gene encoding CUL4 is amplified in breast and liver cancer. "We don't know the exact mechanism whereby CUL4 could play a role in cancer, but its abundance in the cell may cause a defect in the checkpoint pathway. And that's what we're studying now," said Xiong....New method identifies chromosome changes in malignant cells
...ed their technique to yeast cells as well as human breast cancer cells and found many previously unknown add...recognized immune system genes that are deleted in breast cancer cells, suggesting possible ways in which these aberrant cells avoid being detected and destro...Support groups aid women with 'breast cancer gene mutations'
...group model intervention for women at high risk of breast cancer will be published in the November 15, 2004 ...mutations have up to a 90 percent lifetime risk of breast or ovarian cancers. As a result, they must address difficult issues that can lead to depression and ...Estrogen protects male rats from aortic aneurysms
...AAs, including how tamoxifen, a drug used to treat breast cancer, affects the process of AAA formation. The research was supported by the National Institutes of Health, the Jobst Vascular Research Fund, the Lifeline Foundation and the University of Michigan. Gorav Ailawadi, M.D., a U-M resident in surgery, ...Normal cells in tumors may aid cancer growth
...lleagues analyzed 134 tissue samples from invasive breast tumors. They examined stromal cells known as fibroblasts, the major component of the tumor stroma. Fibroblasts produce the fibrous scaffolding in tumors and normal tissues. (Stromal cells also include immune cells, fat cells and blood vessel cells.) ...Excess dietary fat accelerates breast cancer by altering the activity of a group of genes
...by scientists at the UAB on experimentally induced breast cancer tumours in laboratory rats show that an exc...n the diet, commonly known as omega-6, accelerates breast cancer, increasing the malignancy of the disease. The research team at the Departament de Biologia C...Combination hormone therapy doubles breast density and quadruples risk of abnormal mammograms
...rapy for one year experience a twofold increase in breast density a known risk factor for breast cancer and a quadrupled risk of having an abnormal mammogram, according to new findings from a sub-...Hormone therapy's effect on breast density is not the same for all women, Group Health study finds
...ally estrogen plus progesterone therapy, increases breast density, a change that makes it harder to detect breast cancer on mammograms. But it hasn't been clear whether this increase happens for all women, or wheth...High fiber intake reduces estrogen levels in Latina women, according to researchers
.... Because high estrogen levels have been linked to breast cancer, this finding could provide a significant step toward preventing breast cancer. Their findings are being presented at the American Association for Cancer Research (AACR) th...Promising new preventative treatment option for population of men at high risk of prostate cancer
...TTLE -- Toremifene, a drug currently used to treat breast cancer in women, was found to reduce the incidence of prostate cancer for men at high risk for the disease. In a study presented today at the American Association for Cancer Research Third Annual International Conference on Frontiers in Cancer Prev...Newly discovered protein suggests novel tumorigenic pathway
... are found in a variety of human cancers including breast and prostate cancers. Approximately 20 percent of the mutations are located in a segment of 70 amino acids at the C-terminus of PTEN. These mutations lead to the rapid degradation of PTEN in cells, indicating that this region is critical for ensuri...Potential new oncogene may be missing link in cancer-causing chain
...ct. 25. "In several types of human cancer, such as breast and colon cancer, a key cell signaling pathway tha...nt responsible for certain types of cancer such as breast cancer. "We believe LRP6 may be the missing link, the long-sought component that turns up the activi...Medical informatics project targets ovarian, breast cancers
...elp doctors better understand the damage caused by breast and ovarian cancers. Funded by the National Cancer...work will lead to better therapies for ovarian and breast cancer patients." The researchers will study the genetic and molecular consequences of DNA modificat...NIH funds rare childhood disease to provide insights into the origins of adult cancer
...ia, and the BRCA1 genetic mutations that can cause breast cancer later in life. "The detailed clinical information available through the DBA registry will allow researchers to gain important insights into cancer risk and birth defects. Knowledge gained from studying the biology of this disorder will u...Common household fragrances may be harming aquatic wildlife, study finds
...aces of the compound were found in human body fat, breast milk and blood. Germany has placed a voluntary ban on musk xylene, although it's still widely used in the United States, except in lipsticks and other products that are applied orally. One problem for consumers is that, when a product has the word "f...