Tag: "breast" at biology news
VCU research: Magnetic nanoparticles for potential cancer treatment
...ials for the treatment of various cancers, such as breast
cancer." Carpenter and his team are working to det...t may be possible for a patient to be screened for breast
cancer using MRI techniques with engineered enhanced ferrites as the MRI contrast agent. He said if ...
Scientists discover scaramanga gene's bond with breast cancer
...nt of breasts. This has important implications for breast
cancer, as reported in the journal Genes and Devel...Man with the Golden Gun is involved in triggering breast
development. "Identifying the Scaramanga gene is a real advance in our understanding of the early s...
Breast cancer risk increased for African-Americans with mitochondrial DNA variant
...ele are 60 percent more likely to develop invasive breast
cancer than African-American females without that ... mitochondrial DNA are underappreciated factors in breast
carcinogenesis," said Jeffrey Canter, M.D., M.P.H., of the Center for Human Genetics Research at Van...
Researchers find drug that blocks spread of lung cancer in mice
...ng cause of cancer death, killing more people than breast
cancer, prostate cancer and colon cancer combined, according to the American Cancer Society. Lung adenocarcinoma accounts for about 40 percent of lung cancers. Its rate is increasing worldwide, Dr. Shay said, and survival rates are poor because the...
Researchers discover why melanoma is so malignant
...ls underneath the skin of mice. Mice injected with breast
cancer cells or with fibroblast (connective tissue) cancer cells developed tumors, but the tumors didn't spread. Those injected with melanoma cells immediately developed invasive tumors throughout their body, spreading everywhere from the lungs to th...
Other highlights in the September 7 JNCI
...(PR) in women with estrogen receptor (ER)-positive breast
tumors may have important clinical relevance, incl...spond to tamoxifen, according to a new study. Many breast
cancer therapies have been developed for women whose tumors overexpress ER (i.e., ER-positive tumors...
Researchers zero in on estrogen's role in breast-cancer cell growth
...n can promote the proliferation and progression of breast
cancer, because the balance of co-activators and co-repressors involved in normal gene transcription is altered," said Benita S. Katzenellenbogen, a Swanlund Professor of Cell and Developmental Biology at Illinois. She also is a professor of molecula...
Blood test for colon cancer risk to be goal of Hopkins project
...Feinberg. "The BRCA1 and BRCA2 genes implicated in breast
and ovarian cancers are great examples, but they are applicable only to a small percentage -- less than one percent -- of women." But while the troublesome BRCA1 and BRCA2 genes stem from changes in the sequence of the DNA itself, the problems with ...
Cancer gene MYC shown to activate gene involved in metastasis
... play a role in a wide range of cancers, including breast
and lung cancers and lymphomas. With the help of Wistar's genomics facility headed by associate professor Louise C. Showe, Ph.D., McMahon and his colleagues sifted through nearly 10,000 genes before identifying MTA1 as a MYC target. Among the pressin...
Purdue scientists treat cancer with RNA nanotechnology
...orked well enough to interrupt the growth of human breast
cancer cells and leukemia model lymphocytes in lab...ing.' The nanoparticles had done their work on the breast
cancer cell cultures within a few days." Additionally, the team found that the nanoparticles complet...
Breast tumors in mice eradicated using cancer vaccine
...monocytogenes, they can cure mice with established breast
tumors. Cancer vaccines, which are more properly d...-2/Neu is overexpressed in 20 to 40 percent of all breast
cancers and also present in many cancers of the ovaries, lung, pancreas, and gastrointestinal tract....
Breast cancer advance
...ered that several 'ADAMTS' genes are turned off in breast
cancer compared to normal breast
tissue, while others are switched on. These genes could be targets for the development of 'smart' dr...
Scientists identify two key genes linked to aggressive breast cancers
...ed Notch1 and Jagged1 are linkedto more aggressive breast
cancers and that patients are less likely to survi...Notch pathway may be overactive in some aggressive breast
cancers. "We're excited by this discovery because there are drugs already in development that interf...
Molecular pathway linked to breast cancer recurrence
...etic pathway that is involved in the recurrence of breast
cancer and identifies a potential target for devel... The research makes use of a unique mouse model of breast
cancer that provides insight into the molecular and cellular events that lead not only to tumor deve...
Columbia scientists develop cancer terminator viruses
...tor" virus, which selectively replicates and kills breast
cancer cells in mice. Human breast
tumor xenografts were established on both sides of immune-deficient mice. Results found that treati...
Understanding IGF-1: Jefferson researcher sees drug potential in targeting enzyme
...ceptor, -catenin, a protein important in colon and breast
cancer is turned on. "We're the first ones to discover that IRS-1 goes to the cell nucleus, where it binds a protein, -catenin, in the nucleus that regulates RNA polymerase 1, the enzyme that controls cell size," he explains. He doesn't think that IR...
Other highlights in the September 21 JNCI
...years is associated with increases in mammographic breast
density. Mammographic density has been associated ... decreased sensitivity of mammograms and increased breast
cancer risk. To assess the affect of estrogen-plus-progestin therapy on mammographic density, Anne M...
Tissue stiffness drives tumor formation
...ng-used a three-dimensional gel on which they grew breast
cancer cells and could precisely control and measu...reased in connective tissue, the cells of a normal breast
duct started to grow atypically, causing the structure of the duct to degrade, as the uncontrolled c...
Researchers discover gene mutations associate with a chronic pain syndrome
... divisions that lead to tumor formation, including breast
cancer. Cells depleted of SEPT9 often fail to complete normal cell division. HNA is the first genetic disease found to be caused by a mutation in a gene of the septin family. According to the authors of the SEPT9 gene mutations study, SEPT9 has parti...
Questionnaire identifies women at risk of inherited breast or ovarian cancer
...ted genetic mutations that increase their risk for breast
or ovarian cancer. In the November issue of the j...s shown that about 20 percent of women who develop breast
or ovarian cancer have family histories that suggest they may have inherited a mutation that would p...
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