Meat and two neutrons -- the key to a longer life
...irst time that food enriched with natural isotopes builds bodily components that are more resistant to the processes of ageing. The concept has been demonstrated in worms and researchers hope that the same concept can help extend human life and reduce the risk of cancer and other diseases of ageing, reports...Clinical trial for diabetic macular edema
...ter for the trial. This Phase 2 clinical trial builds on the results of a phase 1 trial (which was supported by an Innovative Grant Award from JDRF), which showed the ability of ranibizumab to improve visual acuity in patients with diabetic macular edema. Visual acuity was assessed using a reading char...Healthy coastal wetlands would adapt to rising oceans
...th a steady, moderate rise in sea level, the model builds a marsh platform and channel network (that rises) with the rate of sea-level rise, meaning water depths and biological productivity remain temporarily constant," said the new report. "If the vegetation is intact, it holds the system in place and en...Overfishing large sharks impacts entire marine ecosystem, shrinks shellfish supply
... Hill and co-leader of the study. The research builds upon an earlier study by Myers and Baum, published in Science in 2003, which used data from commercial fisheries to show rapid declines in the great sharks of the northwest Atlantic since the mid-1980s. Now, by examining a dozen different research su...Switching genes to overdrive improves muscular dystrophy symptoms in mice
...bers to contract. Part of the reason that exercise builds stronger muscles is that it increases PGC-1alpha activity. Conversely, disease or lack of exercise reduces PGC-1alpha activity, causing a loss of NMJ function and weakening, or atrophying, of muscles. Spiegelmans team had previously bred a strain o...Enhancing chemotherapy's efficacy: New agent has synergistic effect with standard drugs
...and microtubule-targeting inhibitors"). The work builds on prior findings published by the team in the Proceedings of the National Academy of Sciences, which first identified MCP compounds, and demonstrated that MCP compounds have the ability to inhibit the growth of cultured cancer cells that depend on i...Class of PCB's causes developmental abnormalities in rat pups
...ied in human populations, and fast." The finding builds on recent cell culture studies by co-author Isaac Pessah, PhD, professor of molecular biosciences at University of California, Davis, showing that non-coplanar PCBs significantly influence chemical and electrical signaling between neurons that affect...Researchers find ways to reduce side effects in the treatment of damaging protein plaques
COLUMBIA, Mo. When protein plaque builds up in the blood, it can result in serious diseases such as heart disease and Alzheimer's. Cyclooxygenase (COX) inhibitors, a class of drugs under investigation for the treatment of one cause of plaque build-up, also exhibit negative side effects. R...Minuscule molecules pack a powerful punch
...quences for human health and disease. "Our work builds upon the sequences of the human and mouse genomes, the power of computer analysis and microarray work and exemplifies why whole-organism research can bring understanding that cannot be developed in any other way." The study emphasizes the value of ...Puzzling plankton yield secrets to role in evolution/global photosynthesis
...nan adaptive process in Ostreococcus. "This work builds on the communitys emerging understanding about how carbon fixation is carried out by picoplankton," said Brian Palenik, lead author and researcher at the Scripps Institution of Oceanography, University of California, San Diego. "From an applied per...New Arizona alliance aims to boost technologies for medical diagnostics and human health
...ed from this research," said Mobley. The effort builds on the vast knowledge generated by the Human Genome Project, which has mapped roughly 25,000 genes. Each gene codes for the production of protein, but with all the modifications possible to both the gene transcript and protein, the human body could ...Vitamin extends life in yeast, Dartmouth Medical School researchers find
... resembles sirtuins found in humans. The new work builds on Brenners prior discovery of the vitamin, termed NR (nicotinamide riboside), a natural product found in milk. Like the B3 vitamin, niacin, NR is a precursor to a versatile cellular factor that is vital for all life. The factor, called NAD, shor...Scientists identify new strategy for preventing acute and chronic brain disease
...of amyloid-beta proteins (AB) because Amyloid-beta builds up to abnormally high levels in the brains of people with AD and is widely suspected to cause the disease. "We wanted to pursue a complementary strategy and try to make the brain more resistant to A-Beta without having to change the levels of A-Bet...Story ideas from the Journal of Lipid Research
...tists are now trying to understand how cholesterol builds up in these cells, especially in cellular organelles called lysosomes that are known for degrading cholesterol. W. Gray Jerome and colleagues noticed that when cholesterol accumulates in lysosomes, they become less acidic, which makes them less act...CSHL selected for odENCODE Data Coordination Center
... President Bruce Stillman. The modENCODE project builds on the foundation of the ENCyclopedia of DNA Elements (ENCODE) consortium that is building a catalog of all of the elements in the human genome crucial to biological function. The modENCODE initiative is using the fruit fly and roundworm as model org...New genetic data overturn long-held theory of limb development
...ws that the genetic and developmental toolkit that builds limbs with fingers and toes was around long before the acquisition of limbs, according to the scientists, and that this toolkit exists in some primitive form in a living primitive bony fish, the paddlefish. "We found that the genetic capability seen ...Research center unites biomedical competitors to fund medical technology development
...ia, between our students and industry." "MIMTEC builds upon existing partnerships and collaborations, which use UC research core facilities like the Center for Surgical Innovation," adds Doarn. "The MIMTEC partnership provides a platform for innovation and discovery, bringing industry, government and ac...The fisherman is a predator like any other
...ovy species, a pelagic fish that usually lives and builds up off the coasts. These methods shed light on the spatial interactions between fish and fishermen and enabled researchers to devise new tools that could improve monitoring and hence operational fish stock management. The characteristics of moveme......cluding humans, helps us understand what evolution builds on when it produces seemingly radically new phenotypes, Amdam says.......he whole, the strategy succeeded. Roberts method builds on his co-discovery, in 1997, of a simple method forbuilding libraries of trillions of short proteins, or peptides. Unlike DNA, which can be copied and multiplied millions of times withpolymerase chain reaction (PCR), proteins cannot be copied dire...