Early life stress can inhibit development of brain-cell communication zones, UCI study finds
...h stress levels during infancy and early childhood can lead to the poor development of communication zone... a key messenger for stress, the neuropeptide CRH, can inhibit the normal growth of dendrites, which are branch-like protrusions of neurons that send and r...International human genome sequencing consortium describes finished human genome sequence
...Access to uninterrupted stretches of sequenced DNA can greatly assist researchers hunting for genes and the neighboring DNA sequences that may regulate their activity, dramatically cutting the effort and expense required to find regions of the human genome that may contain small and often rare variants i...For inferring the biological tree of life, simple is better
...n gets the wrong tree because it assumes evolution can be accurately captured in a statistical model, but...on said. "Parsimony makes fewer assumptions, so it can cope with a complex reality better." The results published in Nature suggest that scientists should ...Academics find that the finger of destiny points their way
... levels of oestrogen and testosterone a person has can be seen in the relative length of their index (sec... had more oestrogen. The difference in the lengths can be small as little as two or three per cent but important. A survey of the finger lengths of over ...OHSU study: Bacterial switching mechanism key to survival
...luding those that cause life-threatening diseases, can stay alive in adverse environmental conditions. Th...have access to another sugar, such as xylose, they can use this carbohydrate as a carbon source and meet their energy needs this way. Interestingly, if you...New DNA repair enzyme makes mistakes to save lives of cells
...yed at a most critical time, when typically damage can halt replication altogether, may save the cell fro...damaged. If a problem somehow evades detection, it can prevent DNA from being replicated or result in a mutation in the copied DNA. The researchers found ...Molecular mechanism sheds light on neurodegenerative diseases
...f idle and damaged proteins remain, their presence can affect cell behavior. Misfolded and damaged proteins are common to all human neurodegenerative diseases. They clump together to form toxic aggregates that destroy cell function and cause disease. Morimoto's team is the first to demonstrate in living...Molecule that helps DNA replicate may make good target for cancer therapy
... how DNA replicates itself: Before DNA replication can begin, the two strands in the DNA double helix mus...m spontaneously sticking together again. Only then can the star of the show--DNA polymerase alpha, the enzyme complex that synthesizes new DNA strands--be ...ENCODE consortium publishes scientific strategy
...ty of the problem. No single experimental approach can be used to identify all functional elements, and m...so expanding the portfolio of technologies that we can apply to them," said Peter Good, Ph.D., NHGRI's program director for genome informatics. Recipients ...New genomic method can identify disease-causing genes
...mouse genome is similar to that of humans and mice can be genetically manipulated. Because of this, the mouse is the most commonly used experimental model for studying human disease, and the "mouse to man" approach is widely used. Since analyses of mouse genetic models by traditional methods are very tim...Mouse study: 'Critical' Down syndrome region isn't
...ns Institute of Genetic Medicine. "Now researchers can take a deep breath, accept that the syndrome is co...a triple genetic dose might be modifiable -- if we can figure out the key players." As part of this effort, Olson used a technique to precisely duplicate a...Clues to improving TB treatment
... in tuberculosis bacteria suggest that the protein can be disabled when it binds to certain other molecules. With this protein sidelined, tuberculosis bacteria become more sensitive to treatment by a "second-line" drug called ethionamide, or ETH. Second-line drugs such as ETH may prove useful in trea...Study is looking at ways to help stroke survivors regain lost motor skills
...pe that by stimulating the surface of the brain we can permanently reverse paralysis and rekindle patient...n patients have had a stroke, there is not much we can currently offer beyond physical rehabilitation to improve their motor functions." Researchers ...UF scientist: 'Brain' in a dish acts as autopilot, living computer
... Florida scientist has grown a living "brain" that can fly a simulated plane, giving scientists a novel w...your brain, and learning and the memory process, I can ask you questions about when you were 5 years old and you can retrieve information. That's a tremend...Single genetic defect links many risk factors for heart disease and stroke
...emonstrated that a single change in a person's DNA can contribute to a range of life-shortening risk fact... blueprint and unloads its amino-acid cargo, which can then be incorporated into the elongating protein chain. The defective base the researchers pinpoint...Are yeast cells bringing us a step closer in treating obesity?
...blood - as in diabetes, for example - this process can break down. The discovery that receptor proteins r...xistence in human beings. Given that this research can raise a lot of questions for patients, we ask you to please refer questions in your report or articl...Researchers discover gene mutations for Parkinson's disease
...der" populations, such as the Basques, researchers can use this information to isolate interacting genes ...hen certain nerve cells die or become impaired and can no longer produce dopamine. Without it, individuals can develop tremor or trembling in hands, arms, ...NIH funds new bioinformatics resources at UT Southwestern
...ll include databases and software that researchers can use to improve drug discovery and vaccine developm...ute to the development of disease. From this, they can better devise drugs or treatment options for type I diabetes, multiple sclerosis, systemic lupus ery...Genetics play role in response to most common asthma drug
...erapy based on patients' genetic patterns. "If we can pinpoint which individuals will do better with a certain type of therapy, we can improve their lives more quickly and save them -- and the healthcare system -- the expense and risk ...Wendell Berry to give 'Renewing Husbandry' lecture during scientific meetings in Seattle
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