St. Jude shows gene test not needed if cancer drug given in low doses
...ldren's Research Hospital have shown that when the cancer drug irinotecan is given in low doses for multiple days, it eliminates the need to delay treatment to perform costly genetic testing that determines if the patient is at risk for serious treatment side effects, such as neutropenia. Neutropenia is an ...American Chemical Society's Weekly PressPac -- June 13, 2007
...avian flu drugs Toward a much-needed new test for cancer of the urinary bladder Protein-enriched milk may ...EDIATE RELEASE Toward a much-needed new test for cancer of the urinary bladder Journal of Proteome Research Progress toward development of a much-needed...How the Biotech Revolution Is Changing the Way We Fight Disease
...al Cancer Institute announced the beginning of the cancer genome atlas project, a large-scale endeavor to map every gene implicated in cancer and the first step toward development of new therapies for treating this still baffling disease. Thi...Inflammation is at the origin and progression of diseases such as diabetes or cancer
...nclusive study linking inflammation, infection and cancer in Nature earlier this year. Another internationally renowned scientist is Gabriel Nuez, from the University of Michigan Medical School (USA), whose laboratory has been studying the autoinflammatory syndrome. Jorge Moscat, from Genome Research Instit......ar steps are needed for a mouse to develop a human cancer and such mice are used to learn how to treat or p...resent in which subsequent steps can occur so that cancer develops. If we now improve that 10,000-fold, the pool of cells [with translocated chromosomes] m...Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
TORONTO, June 15 Current cancer therapies often succeed at initially eliminating t...oir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual metastasis. Now, r...CSHL scientists successfully target tumor microenvironment to stop cancer growth
... tumor progression and that eliminating EPCs stops cancer growth. Using sophisticated high-resolution micros...ytometry, they zeroed in on the earliest stages of cancer progression and identified the role of EPCs in generating blood vessels that allow cancers to grow. ...Brazil's first oncology biotech launches
...e of the most promising for the development of new cancer therapies. There are tremendous clinical research opportunities in Brazil. You have a country with many very talented laboratory and clinical researchers, theres a large population to draw patients from, and we know we can have great confidence in th...Study could impact noninvasive treatment of cancer tumors
...ile not what they expected could end up impacting cancer treatment. Devireddy and Monroe initiated a study ... cells, which are derived from a specific cervical cancer cell line, or Jurkat cells, cancer cells commonly used in research due to their abnormally rapid gro...St. Jude study yields secrets of chromosome movement
...of other chromosomesa problem that is prevalent in cancer and can cause miscarriages or disease, such as Down syndrome. St. Jude researchers made their discovery by tracking the activity of a small army of molecules with exotic names like argonaute (Ago1) and dicer; these molecules help maintain a specia......by targeting multiple genes. Complex diseases like cancer often contain defects in several processes controlled by kinases. It works a bit like getting a recommendation from Amazon, says Dr. Peer Bork, group leader at EMBL. The fact that certain books have been bought by the same customers tells you that...Screening approach leads to discovery of gene linked to breast cancer
... form that increases the risk of developing breast cancer at an early age. Rather, the mutation arises durin...rs state. The genetic material within many human cancer cells is in such disarray that there can be numerous gene mutations," says the study's co-senior aut...Clocking in and out of gene expression
...he clock needs to be set off. In studies of breast cancer cells, OMalley and his colleagues showed how the clock works. Using steroid receptor coactivator-3 (SRC-3), they demonstrated that activation requires addition of a phosphate molecule to the protein at one spot and addition of an ubiquitin molecule a...Can a Mediterranean diet help prevent colon cancer?
...all healthy eating plans the same when it comes to cancer prevention" Researchers at the University of Mic...ll eating patterns appear to be more important for cancer prevention than intakes of specific nutrients or food groups. We hope this study will give us an ind...UVa-led team uncovers important secret in gene replication
...rue for both cell lines studied, the HeLa cervical cancer cell line and a normal cell line (lymphocytic cell...in the lymphocytes, even though the HeLa cells are cancer cells with scrambled genes, Dutta said. The chromatin packaging predictions were approximately compa...Bacteria ferry nanoparticles into cells for early diagnosis, treatment
... Experiments were carried out in cultures of human cancer cells, including intestinal, oral, liver, ovarian and breast cancer cells. The researchers also tested their method on live mice and showed how the technique could be u...Lung and bladder cancer deaths continue decades after arsenic exposure
...osure appears to continue causing lung and bladder cancer deaths years after exposure ends, according to a s...der cancer, but researchers dont yet know how long cancer risk remains elevated after arsenic exposure. The drinking water in a region of northern Chile becam...Other highlights in JNCI, June 12
..., and colleagues assessed the relationship between cancer incidence and patients CD4 cell counts at the time of AIDS diagnosis by comparing cancer incidence in AIDS patients before and after HAART became available. After 1996, the incidence of ...NIH awards nearly $21 million to fund cutting-edge research equipment
... Denver and Health Sciences Center will facilitate cancer research and other studies. Also, a pulsed electr...asurements of intact proteinswill be housed in the cancer center and mass spectrometry/proteomics facility to ensure optimal performance and research producti...BRCA2 carriers at increased risk for deadly form of prostate cancer
...e likely to develop aggressive and lethal prostate cancer than noncarriers, according to a study published o... BRCA2 gene are associated with increased prostate cancer risk, but it has been unclear whether they are related to progression of the disease. Laufey Trygg...