Tag: "cancerous" at biology news

Pitt scientists study how cancer cells get out of control

...d how a single aberrant cell can duplicate to form cancerous tumors, suggesting a specific protein mechanism as a target for the treatment of cancer, they report in a paper titled "Spindle Multipolarity Is Prevented by Centrosomal Clustering," published in the Jan. 7 issue of Science . The team, led by Willi...

University of Pittsburgh receives award to study new theory of breast cancer development

...e to rapidly growing cells that form the bulk of a cancerous tumor. "Much like a seed is necessary for the growth of a plant, we believe that tumor stem cells exist at the heart of a tumor and perpetuate the growth of cancer," explained Dr. Donnenberg, who is assistant professor of surgery at the University of...

New cancer gene identified by Memorial Sloan-Kettering scientists

...ays that are required to transform normal cells to cancerous ones. The researchers found that when they "knocked out" the Pokemon gene in mice, that transformation was blocked and cells do not become cancerous. (Knocking out a gene means inactivating it through genetic engineering.) A drug that could block the...

How do cells travel through our bodies?

... the wrong time and place, for example in a tumor, cancerous cells may spread throughout the body and form metastases. It was already known that n-cofilin can break down actin fibers in the test tube, but Walter Witke and colleagues Christine Gurniak and Emerald Perlas wanted to know if it played a role in ce...

UCLA researchers detail the evolution of quantum dot imaging in the journal Science

... of different colored qdots that would "label" the cancerous cells. Once they're gathered at the tumor site, the positrons emitted from the qdots could be imaged with PET scanners now in use in clinics throughout the country. The scan would indicate the presence and location of a tumor. An "optical barcode" of...

Circles of DNA might help predict success of stem cell transplantation

...liminate the patients' own stem cells that produce cancerous white cells or faulty red cells and replace them with healthy stem cells from donors. If the transplants succeed, the donated stem cells repopulate the blood with healthy red and white cells. The St. Jude team showed that the more copies of tiny rin...

Study shows naturally occurring proteins protect against rapid tumor growth

...d spread of cancer, offering key insights into why cancerous tumors grow at different rates among different ind...d of how genetic defects convert normal cells into cancerous cells, much less is known about how the body defends itself against the growth of cancer. Our study ...

Common virus becomes a new target for cancer treatment

...wn blood to recognize the antigens and destroy the cancerous cells harboring the virus. The treatment was well tolerated in all but one patient, who had pre-existing facial swelling that increased after the infusion. "Radiation and chemotherapy, the traditional treatments for nasopharyngeal carcinoma, frequen...

U-M scientist to talk about tissue engineering at AAAS

...d. To heal a large wound, like that created when a cancerous tumor is removed from the jaw, that often means taking a bone graft from someplace like the hip. That approach has problems both for the wound at the donor site and for the site where it is implanted. In addition to discussing the sometimes-messy rea...

Source of molecular triggers in cutaneous T cell lymphoma identified

...esearch group reported that, like all T cells, the cancerous CTCL cells require antigenic stimuli delivered by specialized dendritic cells of the epidermis, referred to as Langerhans cells (LC), in order to replicate. To determine the nature of the activating antigen, Carole Berger , a research scientist in ...

A new 'strategic partner' in cancer development

...ing the body's connective tissues. L1 also renders cancerous cells more resistant to stress and helps them survive in adverse conditions. These attributes can help cancer to grow and spread. Thus, L1 protein appears to act as a strategic partner that assists in the development of colon cancer tumors. Working i...

Yeast network prevents damage by oxygen radicals

...control mechanisms are important guardians against cancerous changes in human cells," says Dr. Richard Kolodner, LICR Member and senior author of the study. "However, the effects of ROS on these cellular responses have not been well characterized. We've now identified a group of genes that cooperate to suppres...

Anti cancer virotherapy well tolerated in first human administration, research finds

...stration of a single dose of CVA21 directly into a cancerous tumour was well tolerated. "Administration of CVA21 may be of potential therapeutic benefit in controlling the spread of melanoma," Professor Shafren said. CVA21 is one of a small group of naturally occurring rather than genetically modified viruses ...

JCI table of contents April 1, 2005

...promoting tumor growth and decreasing death of the cancerous cells. Thus, the cholesterol content of lipid rafts in cell membranes may mediate tumor survival and may be a potential target involved in tumor progression. TITLE: Cholesterol targeting alters lipid raft composition and cell survival in prostate c...

TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas

...to commit suicide--ridding the body of potentially cancerous cells. "The study's findings strongly suggest that... However, such rogue cells can still become fully cancerous if they succeed in eliminating p53 activity, in effect silencing the command to commit suicide. This...

Components in grapes inhibit enzyme key to proliferation of cancer cells

...s that can reduce the activity of that enzyme, the cancerous cells will die." The synergistic activity involves specific phytochemicals from the proanthocyanidin and anthocyanin classes of the varied flavonoid family. They worked more effectively against the enzyme than do the previously identified flavonoids ...

New technique finds molecules necessary for cancer metastasis

...searchers destroyed these particular proteins, the cancerous cells show a significant decrease in their ability to invade healthy cells a finding that provides a new target for badly needed drugs. Although most cancer deaths occur from metastasis, not from the original cancer itself, no drug treatments are cu...

Genetic testing could bolster radiotherapy's effectiveness against cancer

...ctors to first obtain the 'genetic fingerprint' of cancerous tissue in order to find out which treatment method will be most effective." The research appears in this week's issue of the Journal of Biochemistry. Li's co-authors include researchers from the City of Hope National Medical Center, Bio-Rad Laborator...

Lewis C. Cantley, Ph.D., receives Pezcoller-AACR International Award for Cancer Research

...y has helped to explain how normal cells turn into cancerous cells, and in so doing, has provided the scientific community with an extremely important target in terms of future cancer treatments." A summa cum laude graduate of West Virginia Wesleyan College in 1971, Cantley obtained a doctorate in Biophysical ...

Scientists announce world's most sensitive cancer test

... which varies most dramatically between normal and cancerous cells." This makes stretching the most sensitive method known for identifying cancer. Just 50 tumour cells are needed in a sample for the optical stretcher to diagnose cancer, contrasting with traditional methods which need 10,000 to 100,000 cells. W...

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(Date:10/15/2014)... Fred Alt will be awarded the 44th Rosenstiel Award ... for his pioneering research exploring the mechanisms of genomic ... cancer cells. Alt is the second alumnus to win ... Nobel Prize in 2003. , Alt is the Charles ... at Harvard Medical School and an investigator at the ...
(Date:10/14/2014)... house fly genome for the first time, revealing robust ... that thrives in pathogen-rich dung piles and garbage heaps. ... Genome Biology , will increase understanding of house ... adapt to resist insecticides, which could lead to novel ... and transmit more than 100 human and animal diseases, ...
(Date:10/14/2014)... of scientists led by researchers at the University ... of Miami Miller School of Medicine (UMMSM) have ... underlying bipolar (manic depressive) disorder, a breakthrough that ... affective disorder, as well as depression and other ... online this week in Nature Molecular Psychiatry ...
Breaking Biology News(10 mins):Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2House fly genome reveals expanded immune system 2Rare genetic disease protects against bipolar disorder 2Rare genetic disease protects against bipolar disorder 3
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