Columbia University Medical Center researchers discover potential mechanism for tumor growth
...lls that may promote initiation and progression of cancerous tumors. In a study published in the December issue of Cancer Cell, the team showed that stem and progenitor cells are susceptible to a specific error during cell division that can result in severe chromosomal defects. This susceptibility may explain ...UK working with 20/20 GeneSystems
...from persons with early-stage lung cancer detected cancerous nodules several years before they were identified using advanced CT scans. This new data directed to early detection and screening is expected to be presented in early 2006 to the National Cancer Institute (NCI) Early Detection Research Network. ...Also in the December 21 Journal of the National Cancer Institute
...vical tumors. The authors conclude that high-grade cancerous lesions in the female genital tract share a common...ithelium and make the tissue more likely to accept cancerous cells. Contacts: Article: Annette Tuffs, Leiterin der Pressestelle, 06221-56-45-36, Annette_Tuff...File compression can expand mammography's power
...be benign cysts with smooth edges, for example, or cancerous tumors with rough edges - up to large-scale patterns in tissue fiber. "The edges of tumors are where growth occurs, and they tell radiologists whether what they see is a tumor or not," Lucier said. "You have to keep all these features intact when you...Role of microRNA identified in thyroid cancer
...ny strands of RNA is enough to clearly distinguish cancerous thyroid tissue from otherwise normal tissue, scien...d 23 miRNAs that were significantly altered in the cancerous tissue when compared with the normal samples, with three of the miRs miR-146, miR-221 and miR-222 ...Mechanism for Epstein-Barr virus protein's role in blood cancers discovered
...ransform human B cells from the immune system into cancerous cells, which can lead to B-cell lymphomas. Now, they have found that the viral protein--called EBNA3C (for EBV nuclear antigen)--mediates the degradation of the retinoblastoma protein, an important molecular brake for cell proliferation. Erle S. Robe...Loosen leash on cancer protein 'watchdog,' researchers say
...ad a family trait that typically made them develop cancerous lesions in their intestines, but our main goal was to see whether p53 sped up the aging process. Fortunately, we got more kinds of good news than we initially expected." Mice with such a predisposition generally developed about 50 intestinal lesions ...Researchers at Vanderbilt-Ingram Cancer Center uncover clue to explain invasive brain tumors
...d potentially lead to treatment options to prevent cancerous cells from moving to other organs. In animal models, Thompson and Ehtesham found CXCR4 can, in fact, be linked to cell invasion in glioblastoma. "If we look at a brain cancer model in rodents we can see a difference in CXCR4 expression in invasive an...BiovaxID produces long term clinical remission and 95 percent overall survival
...mune system, priming it to recognize and eliminate cancerous lymphoma cells, while sparing normal B-cells. Biov.... Accordingly, Rituxan promotes the elimination of cancerous and normal B-lymphocytes bearing this antigen. Rituxan therapy is typically repeated as necessary at...Curry and cauliflower could halt prostate cancer
...he injections significantly retarded the growth of cancerous tumors. Using PEITC and curcumin in tandem produced even stronger effects. The group went on to evaluate the therapeutic potential of curcumin and PEITC in mice with well-established tumors, and the results showed that PEITC or curcumin alone had lit...A cancer promoting protein shows up in an unexpected place in the cell
...that cause the transformation of normal cells into cancerous cells -- were discovered. One of those oncogenes was ras. There are three ras genes, and K-Ras is the most important in terms of its impact on human cancer. K-Ras acts like as a molecular switch. In its normal form, the protein can be turne...Oncologists could gain therapeutic advantage by targeting telomere protein
...ion to being able to enhance radiosensitization of cancerous tissues by inactivating Rad9, the researchers would like to be able to identify people with mutations in Rad9 because such mutations could predispose a person to cancer. "If Rad9 isn't functioning properly in cells, it can lead to genomic instabilit...Steps made toward overcoming biological obstacles to cell therapy for cancer
...of white blood cells assist the body in destroying cancerous tumors. Among these are CD8+ T cells. The T is for thymus, the gland near the base of the throat that both raises up and weeds out blood cells involved in immune responses. One of the strategies being explored to eradicate established tumors is to i...Adaptation to oxygen deprivation elucidates tumor physiology
...t implications for understanding the physiology of cancerous tumors, the researchers said, suggesting new combination treatment strategies for fighting the disease. When the supply of oxygen from the bloodstream fails to meet demand from body tissues--as can occur in the exercising muscle, ischemic hearts, or ...Think twice before exercising when getting that PET scan
...rawn in higher concentrations (called "uptake") to cancerous areas. The PET scan shows where the radiopharmaceutical is by tracking the gamma ray signals given off by the radionuclides. PET scans are very sensitive, and increased physical activity can create problems in differentiating between normal and patho...Hamster study shows how our brains recognize other individuals
...led immunohistochemistry, is also used to diagnose cancerous cells in humans. Next the brain was frozen with dry ice, shaved into very thin slices using a miniature slow-moving guillotine and then studied under a microscope to determine where the dyes were activated. "Functional MRIs provide similar informatio...Creation of antibiotic in test tube holds promise for better antibiotics
...reventing farnesylation possibly could prevent the cancerous effects, because the mutant protein would no longer be localized at the membrane, Nair said. An accompanying Perspectives article in Science, written by chemist David W. Christianson of the University of Pennsylvania, suggests that nisin's five thioe...Evolutionary biology research techniques predict cancer
...owed for 4.4 years, during which time 37 developed cancerous tumors. Overall, the database used in the study represents more than 32,000 distinct genotypes of different cells within the tumors. Using computational techniques to analyze the data, the researchers calculated measures of diversity inside the tumor...Liver cancer linked to cellular repair pathway
...r to the growing body of evidence suggesting these cancerous tumors are generated by stem-like cells. Stem-like cells in the liver require the Hedgehog pathway for survival, the researchers discovered. These primitive cells are similar to stem cells, but differ in basic ways involving cell reproduction. Hedgeh...Scientists discover new gene responsible for spread of cancer
...of protein genes S100P that causes the spread of cancerous cells from an original tumour to other parts of th...stagenes such as S100P trigger the rapid spread of cancerous secondary tumours to other tissues in the body via the bloodstream a process known as metastasis. A...