JCI table of contents, June 1, 2006
...es and pregnant women often experience physiologic cardiac hypertrophy a beneficial and necessary increase i...ng capacity that allows them to maintain necessary cardiac output under conditions of physiologic stress. However, hypertrophy has recently been recognized as ...When it counts: Shortening imaging time for individuals with suspected heart problems
...ed tomography (SPECT) imaging study--also called a cardiac stress/rest test--can be cut in half using a trade...rdial perfusion SPECT imaging study--also called a cardiac stress/rest test--helps evaluate a patient's heart's blood supply. About 7.5 million individuals--or...PET/CT offers 'superior' view of atherosclerosis plaque, may identify those at risk for heart attack
...d, saying additional research might determine if a cardiac event can be predicted by identifying plaque inflammation. "This is very exciting work," said Josef Machac, SNM's Scientific Program Committee cardiovascular vice chair. "The idea is that atherosclerosis comes in different 'flavors,' and the challe...Patients to benefit from novel technology revolutionizing high-speed molecular imaging
... magnitude (2 minutes vs. today's 20 minutes for a cardiac scan), better image quality (up to two times the i...ECT camera. "The first such application will be in cardiac perfusion (blood flow to the heart), and a multicenter study is planned for the second half of this ...Novel non-invasive imaging technology may allow precise diagnosis of coronary artery disease
...San Diego. "This work presents a new non-invasive cardiac imaging technology for the assessment of ischemic ...n a single imaging session--accurate evaluation of cardiac blood vessel narrowing and blood supply to the heart muscles," said the co-author of "Assessment of ...Nilotinib appears to help chronic myelogenous leukemia patients when standard care fails
...y in their hearts, and one patient experienced two cardiac events. "We believe this issue is manageable with ...ation of this interval is considered a marker of a cardiac arrhythmia. One patient had two adverse cardiac events that were associated with use of nilotinib, a...Study contradicts USA warning that an antidepressant can cause congenital abnormalities
...ound and echocardiogram, which can rule out foetal cardiac problems in early pregnancy. Antidepressants should never be stopped abruptly as this can have serious ramifications for the mother. If a woman does decide, following a discussion with her physician, that she wants to discontinue paroxetine, the drug...Viagra improves high altitude exercise performance up to 45% for some
...ed out of one ventricle of the heart per beat) and cardiac output (stroke volume times heart rate) compared t... insignificant 1%. The study, "Sildenafil improves cardiac output and exercise performance during acute hypoxia but not normoxia," by Andrew R. Hsu, Kimberly E...Finding a cellular Neverland: How stem cells stay childlike
...erate, and some essential ones, such as nerves and cardiac muscle, are not on that list. For human tissue regeneration to become a viable therapy for conditions like neurodegeneration or diabetes, clinicians will likely need to artificially manipulate factors that return adult brain or pancreatic cells to ...Progress being made in exploring potential use of stem cells to treat heart disease
...any cell type) the cues that control multipotent cardiac stem cells (these stem cells, which have less deve...y not only to guide and expand stem cells into the cardiac lineage but also to repress alternative cell fates Developing methods for safe delivery and proper...Reversing 'hibernating' heart muscle focus of UB researchers
...functional myocardium that do not have significant cardiac scar tissue. "These protein studies will be coupled with assays of mitochondrial respiration and of the activity of specific enzymes in the swine model," said Canty. "This work relies on the state-of-the art proteomic research facilities and mass sp...Equine Medical Center records successful year for neonatal foals
...ory problems and complications like infections and cardiac problems are also a threat. Treating a neonatal...fluids, parenteral nutrition, antibiotics, oxygen, cardiac monitoring and other support therapy. And yes, it can be a very expensive process. At the Equine ...Gatekeeping: Penn researchers find new way to open ion channels in cell membranes
...For example, mutations in some channel genes cause cardiac arrhythmias, including a form of the lethal long QT syndrome. Voltage-gated ion channels are also present in the so-called non-excitable cells (such as immune, blood, and bone cells) whose membrane voltage stays largely constant, as opposed to the ...Erectile dysfunction: Incidence rate linked to type and severity of coronary artery disease
...on Trust in London, UK. "All men with ED and no cardiac symptoms need a detailed cardiac assessment, blood pressure measurement, fasting lipid profile and glucose, as well as lifestyle advi...Heart has enough oxygen to survive hypothermia, CPR crucial
...ypothermia to reduce oxygen consumption, to induce cardiac standstill and to restart the heart by rewarming, ...e problems with low blood pressure, low pulse, low cardiac output (the volume of blood the heart can pump per minute), or with oxygen transport to the cells," ...SNM honors outstanding contributors
... honors and has authored more than 300 articles on cardiac PET (flow, viability, glucose transporter function), tumor imaging (angiogenesis) and molecular imaging (gene expression). Blumgart was a pioneer in nuclear medicine in the earlier part of the 20th century and is considered by many to be the father...UT Southwestern researchers find gene mutation that leads to 'broken hearts'
...rokenhearted' for this defect because two kinds of cardiac cells separated, thus causing the heart to fall ap...th high resolution in living animals and to detect cardiac defects that have never been described before", said Dr. Zhe Han, research instructor and co-first /...Preclinical study shows chronic stress agitates ovarian cancer; reducing stress slows tumor growth
... blockers have been shown to be protective against cardiac disease," he says. "No one has studied their effect on chronic stress as it relates to cancer in humans. There is a lot of interest now in this area of combining behavioral interventions to reduce stress, as well as using beta blockers in cancer pati...Nanotechnology enables low-dose treatment of atherosclerotic plaques
...yet need immediate intervention to prevent serious cardiac problems," Winter says. "We think fumagillin nanoparticles potentially could be incorporated into a protocol that includes lipid-lowering statin drugs or dietary changes."Next, the research group plans to study the effect of fumagillin nanoparticles ...... that ACE2 plays a major role in the regulation of cardiac structure and function. TITLE: Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice AUTHOR CONTACT: Thomas M. Coffman Duke University and Durham VA Medica...