Tag: "cartilage" at biology news

Yearling horse auction to benefit equine research

...uctuations in pasture carbohydrate concentrations, cartilage and bone development, the stress of weaning young animals, and changing energy sources for the horse. There also is work on horses' health problems including the debilitating disease laminitis in which there is inflammation within the hoof that may l...

Mouse model of osteoarthritis

...ping bones subsequently develop into the permanent cartilage found in joints. Several members of a family of se... old, the expression of proteins normally found in cartilage was reduced, although at this stage the knee, for example, looked normal. By 7 weeks old (adulthood ...

Researchers discover molecular timekeeper in bone development

...d that they had excess bone and died because their cartilage was converted into bone," said Dr. Olson, who dire...at the defect was in the earliest steps, where the cartilage foundation was being laid and filled with minerals. Before the foundation was complete, minerals wer...

Shark cartilage cancer 'cure' shows danger of pseudoscience

The rising popularity of shark cartilage extract as an anti-cancer treatment is a triumph o...the Dec. 1 issue of Cancer Research. "Since shark cartilage has been promoted as a cancer cure, not only has there has been a measurable decline in shark popula...

Injectable gel could speed repair of torn cartilage

...more effective and less invasive than conventional cartilage repair techniques, which may include extensive sur...en the liquid mixture is injected into areas where cartilage is torn, such as a knee joint, the material hardens into a gel upon exposure to ultraviolet light, l...

A key signaling molecule in osteoarthritis is identified

...the joints of the knees, hips, feet and back. This cartilage breakdown causes the bones to rub against each oth... proliferate and form clusters. Then cracks in the cartilage gradually develop and the cracks are filled with a fibrous tissue; this is considered to be the resu...

Gene therapy promising for growing tooth-supporting bone

...P-7 is part of a family of proteins that regulates cartilage and bone formation. Recent studies have shown that BMPs are present in tooth development and periodontal repair. This study mixed BMP-7 genes with an inactivated virus in a gel-like carrier and injected it into wounds. Giannobile said using a virus, ...

New stem cell source could boost bone marrow success

...chymal progenitor cells cells that generate bone, cartilage and other tissues and can be harvested to generate an abundant supply in a short amount of time. This expandable source of progenitor cells could greatly improve bone marrow transplantation, a painful yet common procedure that currently has a 30 to ...

Emory researchers find more evidence for children's growth spurts, pain

...longate, she says. Growth plates are soft zones of cartilage near the ends of bones. When a young animal is standing, walking or running, pressure may compact the plate, inhibiting growth, Lampl explains....

JCI table of contents March 1, 2005

...ected to great stress over a lifetime of use. The cartilage in a joint sustains damage resulting from friction...in protects joints. First, lubricin preserves the cartilage surface by preventing protein deposition and protecting the cells that make cartilage. Second, lubr...

Gene therapy converts dead bone graft to new, living tissue

...ply this to one of the Holy Grails of orthopedics cartilage repair. Unlike bone, damaged cartilage, even in a ...ically target the genes to the edge of the damaged cartilage during arthroscopic surgery, but we're looking to use the same idea of triggering the cartilage to r...

Study: Testing for joint substance in blood might improve diagnosis of osteoarthritis

... naturally in joints and the fluid that lubricates cartilage might enable doctors to diagnose osteoarthritis of the knee and hip earlier or more accurately, a new study concludes. Improving diagnosis of the painful inflammatory disorder should become increasingly important as baby boomer age, doctors say. The ...

Scientists discover that three overlapping signals in embryo help get the backbone right

...nt, this protein factor is critical in laying down cartilage to make joints, and even plays an important role after birth. Recently, he and Stanford University colleagues showed that noggin may be important in preventing the premature fusion of the bones in the skull, and thus may be critical to allowing the b...

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

... kidney disease late in life, but also may lead to cartilage degeneration and impaired memory and learning abil...aintenance of cognitive function and prevention of cartilage degeneration," Sonntag and his colleagues reported in an article in Endocrinology, published on-line...

Liverpool vet creates pain relief diet for arthritic dogs

...in enzymes (aggrecanase) involved in breaking down cartilage that lines the joint surface but is eroded away in arthritis."...

UCLA researchers discover new method to generate human bone

... way to do spinal fusion. Used in conjunction with cartilage growth, this discovery may completely change the w...ission of advancing the science of bone, ligament, cartilage and skin transplantation. We are pleased to be working with UCLA." Wu and Ting anticipate FDA approv...

JCI table of contents June 1, 2005

...rized by inflammation associated with pathological cartilage and bone formation at the attachment of tendons an...ibit disease progression. New strategies targeting cartilage and bone formation are likely to be required to control the disease. In a study appearing online on...

JCI table of contents July 1, 2005

...evelopment of the bones rely on coordination among cartilage cell (chondrocyte) mass regulation and cartilage structure establishment. Parathyroid hormone-related protein (PTHrP) and Indian hedgehog (Ihh) are ...

Arthritis: What Wnt wrong?

...ynovium (or joint lining) and weak localization to cartilage and bone. In addition, strong Wnt-7b expression m...er inflammatory cytokines were produced in primary cartilage and synovial cells from arthritic versus normal joints. While OA cells did not differ from controls...

Enzyme's newly discovered role may make it target for arthritis treatment

...ccumulation of immune cells can lead to tissue and cartilage damage in joints, causing pain and limiting mobili...-reactivity that they will bind to the mouse's own cartilage and collagen and initiate an inflammation," Pham explains. "This leads to a condition similar to rhe...

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(Date:4/17/2014)... trials to treat tuberculosis could be the basis for ... bacteria, fungal infections and parasites, yet evade resistance, according ... collaborators. , Led by U. of I. chemistry professor ... drug SQ109 attacks the tuberculosis bacterium, how the drug ... to malaria and how targeting multiple pathways reduces ...
(Date:4/17/2014)... West Orange, NJ. April 16, 2014. Kessler Foundation ... for $1.8 million from the Department of Defense ... PhD, is principal investigator for the randomized, double-blinded, ... to improve bone and muscle strength after spinal ... Human Performance & Engineering Research at Kessler Foundation. ...
(Date:4/17/2014)... Occurring in about one per eight hundred births, Down ... frequent genetic cause of intellectual disability. It results from ... a third copy of chromosome 21 (1% of the ... his team in the Department of Genetic Medicine and ... Medicine, published in Nature , shed light on ...
Breaking Biology News(10 mins):Multitarget TB drug could treat other diseases, evade resistance 2Kessler Foundation awarded Department of Defense grant for spinal cord injury research 2Trisomy 21: How an extra little chromosome throws the entire genome off balance 2Trisomy 21: How an extra little chromosome throws the entire genome off balance 3
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