Potent anticancer drug increases function of axons in mouse model of neurodegeneration
...proteins that clump in the brain and elsewhere and cause a host of debilitating diseases. Since many neurod...of axons in nerve cells. Mutations in the tau gene cause neurons to lose their ability to send and carry signals over time. "These are proteins that we all h...Violent ocean motion no magic potion for reefs
... been tied to the production of compounds that can cause tumors in sea turtles and other animals, and resea... This information can help clarify the most likely cause or causes of the HABs....Researchers discover a stem-cell switch lurking within leukemias
...nfer the ability to self-renew. These cancer genes cause leukemia in white blood cell progenitors that have.... The researchers found that only MOZ-TIF2 could cause normal progenitor cells to assume the properties of "leukemic stem cells" most importantly, the abi...Blocking cell suicide switch fails to stop prion damage in mouse brains
...hers knew that prions, the misfolded proteins that cause mad cow disease and other brain disorders, were ki... of the bizarre methods by which prions spread and cause disease, they have only recently gained widespread acceptance as the source of several disorders tha...Tips from the Journals of the American Society for Microbiology
...efrigeration and Frozen Storage Combined A common cause of foodborne disease from poultry products can survive refrigeration and freezing say researchers from Pennsylvania. Their findings appear in the December 2004 issue of the journal Applied and Environmental Microbiology. Campylobacter bacteria are e...Genetic predisposition can play an important role in development of lung cancer
...22/29 issue of JAMA . Lung cancer is the leading cause of death from cancer among men and women in many Western countries, according to background information in the article. Death due to lung cancer in the United States exceeds the death rate from breast, prostate, and colon cancer combined. The domina...Hospital epidemiologists trace outbreak of organism to commonly used wound care equipment
...atients, prior to the outbreak." Since finding the cause of the outbreak at Hopkins, the specific strain of the bacterium involved in the outbreak has not reappeared, even after 11 months of follow-up testing. "Antimicrobial resistance is a growing problem for patient safety in health care settings, such...Essential oils could help to stamp out MRSA
...n unpleasant for patients as their application can cause skin irritation. MRSA is often carried inside the nose which means that patients often have to insert treatments up their nostrils, whereas these essential oils can simply be inhaled to prevent the patient being at risk," added Jacqui. Jacqui works ...Needling chromosomes yields insights into cell division
...n lead to cancer or chromosomal abnormalities that cause birth defects." According to Nicklas, it was known that the two sister chromatids adhered to one another and released at the appropriate time during cell division. However, that understanding was based on biochemical experiments that revealed when th...Scientist discover the cellular roots of graying hair
...scientists have been unable to explain the precise cause of this usually unwelcome transformation. In a rep...s Hospital Boston say they have found the cellular cause of graying hair while investigating the origins of malignant melanoma, the potentially deadly skin c...Drilled shells show extinction's lasting effects
...time has passed since theevent, Vermeij said. The cause of the Pliocene extinction remains unknown. The work ispublished in the Dec. 24 issue of Science ....UGA partners with U of Pennsylvania for bio-defense and infectious disease research project
... phylum Apicomplexa, which includes organisms that cause malaria and toxoplasmosis. NIAID, part of the N... about pathogens and vectors such as bacteria that cause anthrax, plague, and water and food-borne diseases; viruses that cause rabies, Ebola and influenza; ...An unusual RNA structure in the SARS virus offers a promising target for antiviral drugs
...argets s2m. Astroviruses, meanwhile, are a leading cause of gastrointestinal infections, second only to rotaviruses as a cause of childhood diarrhea. In developing countries, diarrhea is a major cause of death in children. A dr...UCSD discovery shows how embryonic stem cells perform 'quality control' inspections
...o their daughter cells. Unrepaired DNA damage will cause genetic instability and, ultimately, cellular transformation into cancer cells." Xu and his team made their discovery while working with embryonic stem cell lines from mice, which possess the same known properties and capabilities as human embryon...New signaling step for key player in Crohn's Disease
...es. NOD2 mutations responsible for Crohn's Disease cause polymorphisms that prevent the NOD2 protein from properly modifying NEMO. These results suggest that this previously unrecognized modification on a component of the major inflammatory signaling pathway in the body helps to integrate inflammatory sign...University of Chicago researchers discovered that humans are a 'privileged' evolutionary lineage
...function mutations in either ASPM or Microcephalin cause microcephaly in humans a severe reduction in the size of the cerebral cortex, the part of the brain responsible for planning, abstract reasoning and other higher cognitive function. The researchers found that both the ASPM and Microcephalin genes sh...Vollum Institute discovery may unlock human genome
...ng of the pathways behind genetic aberrations that cause diabetes, Parkinson's disease, heart disease, cancer and other diseases, he said. The Vollum team's technique, developed in collaboration with scientists at Brookhaven National Laboratory in Upton, N.Y., and State University of New York, Stony Brook,...Federal/private partners launch resource for diabetic kidney disease gene studies
...Center in Washington, D.C. Diabetes is the leading cause of kidney failure in the United States. In 2002, treatment of kidney failure cost Medicare and private insurers $25 billion for more than 400,000 people, 40 percent of whom had diabetes. Twenty to 40 percent of people with type 1 diabetes will develo...Growth of common skin cancer blocked in gene-switch mice
...d seldom metastasize. However, untreated BCCs can cause extensive local tissue damage, and surgical procedures can produce significant scarring in cosmetically sensitive locations such as the face. The Hh signaling pathway plays a key role in normal development, and its dysfunction has been implicated in...Animal experiments more stressful than previously recognized
...e experiments themselves, these daily routines can cause an animal to experience elevated bloodstream concentrations of corticosterone, prolactin, glucose, and epinephrine, all indicators of stress. Impaired immune response has also been recorded in animals after anxiety-producing contact with lab personne...