Doctors link common chemotherapy drug to jawbone necrosis
...orm and appears to be substantially less likely to cause the problem," said Dr. Ruggiero....Researchers discover new gene in colon cancer
...Without 15-PGDH present,unchecked COX-2 goes on to cause abnormal changes on the cellular level, which may lead to tumor development." Previous studies have shown that patients who take nonsteroidal anti-inflammatory drugs (NSAIDs), which are COX-2 inhibitors, have a lower incidence of colon cancer. COX-2 ...Vitamin E in plant seeds could halt prostate, lung cancer, says Purdue scientist
... prior indications that some form of vitamin E may cause cell death in some mouse cell lines, we are the first to provide a mechanism for such an effect." Gamma-tocopherol, though rarely available in vitamin pills, is nevertheless found in abundance in the typical American diet. Many nuts are rich...UCSB makes important advances in studies of retinal detachment
...own stimuli, these cells begin to contract and can cause the retina to tear or re-detach. In humans, PVR is the most common cause of failure of retinal reattachment surgery. It occurs in five to 10 percent of all cases. Essent...Alcohol vulnerability linked to action of insulin
...vity is inhibited, the amount of alcohol needed to cause inebriation decreases. The scientists had also examined different regions of the fly brain to determine where the Protein Kinase had its effect. In the new research they zeroed in on a small group of neurons in the brain, specifically cells producing...Gene vaccine for Alzheimer's disease shows promising results
...ems of mice to fight against amyloid proteins that cause the devastating plaques that are characteristic of Alzheimer's disease. For years scientists have examined the possibility of using a protein-based vaccine to slow the progression of the disease in its early stages. UT Southwestern researchers have c...Cigarette smoking exacerbates alcohol-induced brain damage
...nic, heavy alcohol consumption is already known to cause brain damage. Cigarette smoking can also cause brain damage, both in conjunction with alcohol use as well as independently. These findings have imp...A genetic difference at the opiate receptor gene affects a person's response to alcohol
...intravenous doses of alcohol that were designed to cause breath alcohol concentration (BAC) levels of .02, .04, and .06. Researchers measured subjective intoxication, stimulation, sedation, and mood states at baseline and at each of the three BAC levels. Results indicate that individuals with the G alle...New effects of an antihistaminic against cerebral injury
...ephalic infarcts or traumatisms, the third leading cause of deaths in industrialised countries. In experiments with a model of cerebral ischemia using rats, a team from the Institute of Neurosciences of the Universitat Autnoma de Barcelona (Spain) has observed how the presence of ranitidine reduces neurona...New route to Parkinson's found in cells' 'garbage disposal' system
... mutations in a key gene called parkin are a major cause of Parkinson's disease (PD). Now they have discovered a new mechanism by which the parkin gene can be compromised, a finding that they say could lead to new drugs for the disorder. Andrea Lozano, Senior Scientist at the Toronto Western Research Insti...JCI table of contents, December 15 2004
...e all strains of S. aureus have the potential to cause infection, some appear to be more virulent that ot...mmonly diagnosed malignancy and the second leading cause of death in American men. PC usually moves into the bone and the symptoms are treated by suppression...Return of the Staphylococcus aureus 'superbug'
...e all strains of S. aureus have the potential to cause infection, some appear to be more virulent that others....Microbe's genome promises insight into Earth's carbon and sulfur cycling
... Nature. While everyone is aware that bacteria can cause disease, it's less obvious that these microorganisms play an important part in the global ecosystem. "Having the genome of S. pomeroyi completely sequenced provides an invaluable tool to understand how an ocean bacterium functions and how it affects ...Permanent resistance to antibiotics cannot be prevented
...ave already been found in India. Evolution is the cause of the resistance. However this resistance should disappear again, as resistant fungi and bacteria grow less well in an environment without the substance they are resistant to and are therefore outstripped by their faster-growing non-resistant counte...Balancing 'hysteria and suspicion': Doctors face new responsibilities in 'bioterrorism era'
...Control and Prevention (CDC) -- such as those that cause smallpox, anthrax, botulism, plague, tularemia -- initially present in patients as flu-like symptoms. "You don't want to walk into your doctor's office with flu-like symptoms and be told you might have Ebola," says Clements. "On the other hand...Alfred Sommer awarded prestigious Pollin Prize
...hildren die worldwide each year and the underlying cause of many of these deaths is malnutrition. I applaud efforts like the Pollin Prize that assist and encourage a new generation of researchers, like Parul Christian, to pursue the important discoveries that will continue to save the lives of millions of ...Solving the mechanism of Rett Syndrome
...associated with the brain or nervous system, could cause a neurological developmental disorder remained a p...al for how defective or absent MeCP2 protein might cause Rett Syndrome was that, by failing to attach to methylated CpG dinucleotides, it would fail to repre...Combined stem cell-gene therapy approach seen as potential treatment for cystic fibrosis
...ttractive environment for bacteria to colonize and cause infection. Finding ways to correct the gene defect responsible for CF has been the focus of much research and some clinical studies are even looking at gene therapy approaches. To date, no studies have evaluated the potential of adult stem cells or ...Scientists find impaired chromatin structure formation & imprinted gene involvement in Rett Syndrome
... protein 2) were identified in 1999 as the leading cause of RTT. MECP2 is believed to function as a transcriptional repressor of its downstream genes. When genes need to be silenced so that a protein is not produced in a given cell, methyl groups attach to CpG dinucleotides, which are often clustered in ...Body's biological clock found to affect cardiac rhythm patterns in healthy adults
...t of the research. Cardiac disease is the leading cause of death in the United States, accounting for 29 p... could, however, provide insight to the underlying cause of the disease -- and to therapies that might work better by being timed to the specific phases of t...