Study points toward alternatives for Vioxx and Celebrex
Kingston, Ont. Researchers at Queen's University and the University of Pennsylvania ...have identified one reason why drugs like Celebrex and Vioxx once popular for the treatment of pain and inflammation cause heart problems. ...... Their findings offer the prospect of a new generation of anti-inflammatory drugs that will bypass this issue, says co-author Colin Funk, a professor of Biochemistr...Researchers find potential Celebrex target in lung cancer
A product produced by lung cancer tumors fuels the cells that suppress immune function in patients and may be a target for Celebrex therapy, giving oncologists another weapon to fight cancer, according to a study by researchers at UCLA's Jonsson Cancer Center.... ... Researchers found that PGE2, which is produced normally by epithelial cells but at very high levels in lung cancer and other malig...Celebrex provides a two pronged attack against prostate cancer
PHILADELPHIA--Celecoxib, a selective COX-2 inhibitor with promising anti-cancer properties, has now been found to attack prostate cancer cells in a second way that differs from Vioxx (rofecoxib), another anti-inflammatory drug that also inhibits COX-2....... In studies published in the March 1 issue of the journal Clinical Cancer Research, scientists at the Weill Medical College of Cornell Univer...Painful surgical adhesions may be preventable by taking the COX-2 inhibitor Celebrex, a common oral arthritis drug, just before and immediately after surgery, report researchers at Children's Hospital Boston. Their findings were published in the January 25 online Annals of Surgery.... ...Adhesions bands of scar tissue that bind together two internal body surfaces develop in 55 percent to more t...