Tag: "cells" at biology news
Scientists take next step in understanding potential target for ovarian cancer treatment
... of drugs that can repair the defect in the cancer cells
without interrupting the processes of the normal cell, Mulder said. When you find something that isnt working right in the cancer cells, it suggests possibilities as to how to intervene to fix the problem. Epithelial ovarian cancer is often diagnos...
Gene discovered for type 1 diabetes in children
... the immune system destroys insulin-producing beta cells
in the pancreas and makes patients dependent on fr...pe lectin that is located on the surface of immune cells
and binds to groups of sugars in the body. The role of KIAA0350 needs to be investigated, said Ha...
A decisive step toward a cure for insulin dependent diabetes
...ctive gene. These treatments, combined with a stem cells
regeneration therapy, will relieve patients of all symptoms of diabetes. Dr. Polychronakos notes, While this prospect is still far off, it is realistic, and this study is the first step in the right direction....
Tumor painting revolutionizes fight against cancer
...paint can help surgeons distinguish between cancer cells
and normal brain tissue in the operating room. The...s a better chance of removing all of the cancerous cells
during surgery without injuring surrounding healthy tissue. This is particularly significant in the ...
Co-operation between GSF and clinic improves outlook for sarcoma patients
...of electromagnetic waves. At temperatures of 42 C, cells
begin to die, on account of the heat. The combinat...adern Medical Centre exploits the fact that tumour cells
are more vulnerable at 40 C to the immune system and also to radiotherapy and chemotherapy. In the...
Chromosome glue repairs damaged DNA
...e apart too early, there is a risk of the daughter cells
getting the wrong number of chromosomes, somethin...ghter cell. Another large research question is how cells
repair damaged DNA and consequently prevent cancer, for example. "We have shown that chromosome se...
Major breakthrough in understanding how HIV interferes with infected cell division
... (HIV-1) causes AIDS by depleting essential immune cells
called CD4+T lymphocytes in infected individuals, ... viral protein R (Vpr), which stops infected CD4+T cells
from dividing and as a consequence compromises their immune function. In addition, by arresting cell...
JCI table of contents: July 12, 2007
...(MS), the myelin that surrounds the axons of nerve cells
is attacked by the bodys own T cells, resulting in...odel of human MS. Interestingly, myelin-specific T cells
are found in both healthy individuals as well as patients with MS, thus researchers have been workin...
Cells take risks with their identities
...tion. They worked with embryonic stem cells, liver cells
and white blood cells. We expected to find the l... of the genes in both unspecialized embryonic stem cells
and specialized adult cells. Further experiments confirmed that the majority of inactive genes und...
CU researchers discover evidence of very recent human adaptation
...clude genes that control proteins that help muscle cells
attach to surrounding cells
(mutations of this gene lead to muscular dystrophy), receptors that relate to hearing, genes involve...
Small molecules may explain psoriasis
...d different cellular mechanisms in skin and immune cells
these small RNA molecules may be an important factor in the development of disease. Therapies based on microRNA might therefore in the future become more effective than medicines targeted at individual proteins. We believe that microRNA may also be...
White blood cells are picky about sugar
...eutrophils are mindless killers. These white blood cells
patrol the body and guard against infection by bac...sugar elicits a much stronger reaction from immune cells
than the abundant one, it appears that neutrophils can distinguish between two nearly identical chem...
Antibody retards growth and induces death in liver cancer cells
...pha, or PDGFR. The investigators also analyzed the cells
for their level of activation of the PDGFR gene. ...uman liver cancer cell lines as compared to normal cells
in culture. Dr. Mongas group then treated human and mouse liver cancer cell lines with a monoclon...
Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
...scovery on the development of human embryonic stem cells
by scientists at McMaster University will change h...em cells. It had been thought previously that stem cells
are directly influenced by cells
in the local environment or niche, but the situation may be more co...
New use for a cell toxin found to inhibit survival proteins in cancer cells
...called 2-Methoxy antimycin is selective in killing cells
that have high levels of Bcl-2 and Bcl-xL proteins...pression of these proteins in many types of cancer cells
correlates with resistance to chemotherapy and radiation therapy. Cells with normal levels of Bcl-2 ...
A stepwise retreat: How immune cells catch pathogens
...rom disease our immune system employs macrophages, cells
that roam our body in search of disease-causing bacteria. With the help of long tentacle-like protrusions, macrophages can catch suspicious particles, pull them towards their cell bodies, internalise and destroy them. Using a special microscopy techn...
Ago2 and hematopoiesis
...st that the effector function of miRNA in somatic cells
relies mostly on translational control of gene ex...ategies for the identification of miRNA targets in cells
with individual miRNA overexpression or deficiency, explains Dr. Tarakhovsky....
5 OHSU faculty members singled out for honors
...isms of early morphogenesis, when rapidly dividing cells
first begin to differentiate and organize themselv...on gaining a better understanding of how embryonic cells
modify general cellular mechanisms to generate the earliest features of the embryos body plan. He c...
Scientists find brown fat master switch
... skin of the animals. The PRDM16 gene coaxed those cells
to generate brown fat cells. "These results illust...howed that PRDM16 triggered formation of brown fat cells
in part by turning on a metabolic pathway controlled by PGC-1alpha, which was discovered in Spiegelm...
Modified herpes virus keeps arteries 'free-flowing' following procedures
...virus. The ability to target the smooth muscle cells
that cause the narrowing, and regenerate the endothelial cell lining is an important finding, noted Skelly. This study is an important step in the application of genetically engineered herpes simplex viruses for treatment of vascular disease," S...
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