Tag: "cellular" at biology news
Role of autophagy in tumorigenesis
...f New Jersey, report, for the first time, that the cellular
self-digesting process of autophagy can protect genome integrity lending new insight into the seemingly contradictory roles of autophagy as both a cell survival and tumor suppressor pathway. Using cells that were genetically engineered to lack one c...
Newly identified mechanism for silencing genes points to possible anti-cancer strategies
... new gene-silencing mechanism, one that blocks the cellular
machinery responsible for translating messenger RN...ay, one that led us to a mechanism that blocks the cellular
machinery that produces protein from messenger RNA." In earlier studies, Shiekhattar identified a ...
Nutrition and heredity are genetically linked
...goal in biology is to understand how the principal cellular
functions are integrated so that cells achieve via...atory function to adjust the activity of principal cellular
functions to the richness of the available nutrients. This non metabolic function may explain why se...
Mechanism of microRNAs deciphered
... blocks translation very early on, even before the cellular
machinery needed can assemble. Bound by miR2 a messenger RNA molecule is no longer accessible to ribosomes, the complexes that carry out protein synthesis. "Strikingly, the messenger RNA locked-up in this way looks very similar to a messenger RNA t...
Burroughs Wellcome Fund awards $14M to support physician-scientists
... Wu, M.D., Ph.D. Stanford University Molecular and cellular
mechanisms of cardiac regeneration Mark Nan Wu, M.D., Ph.D. University of Pennsylvania Identification of novel genes that regulate sleep in Drosophila melanogaster ...
Study revises dynamin's role in nerve cell function
...rticle in the journal Science, suggests that a key cellular
enzyme called dynamin 1 is not essential to all sy...sis -- a reverse of the process of transmission of cellular
signaling chemicals, whereby molecular components of the vesicle are retrieved from the synapse surf...
UCSB Assistant Professor Patrick Daugherty wins Young Investigator Award from ACS
...applying emerging biotechnologies to molecular and cellular
engineering. Daughertys group has developed methods to create from scratch tailor-made biomolecules that could allow earlier and more accurate diagnosis of cancer and other diseases. He came to UCSB in 1999 after completing a postdoctoral fellowsh...
Toxoplasmosis infection trick revealed by scientists
...he team used a combination of NMR spectroscopy and cellular
studies to characterise the behaviour and interactions of the parasite protein and host cell sugars. This means that the team have a more detailed picture than ever before of exactly how the parasite recognises and attacks host cells in the body. ...
UF scientists identify cancer virus' genetic targets
...n immune system." Thought to be little more than cellular
debris less than a decade ago, microRNAs are short...A and this paper shows at least one function and a cellular
target. These are important findings."...
Scientists develope a new model of artificial canine skin
...any Affinity Petcare, have developed an artificial cellular
model which faithfully reproduces the characteristics of dogs skin and which will allow, therefore, the carrying out of various lines of research related to skin biology and pathology without the need to use live animals. The basic structure of ski...
Baumann Lab defines proteins that distinguish chromosome ends from DNA double-strand breaks
...istinct from DNA double-strand breaks and that the cellular
machinery that repairs DNA breaks does not act on telomeres. But how repair factors are prevented from acting at chromosome ends has been a hotly debated issue. Over the past decade, several telomeric complexes and structures have been identified and...
Global heartbeat control suggests therapy for beating heart failure
...scientists as a key regulator in the production of cellular
power plants called mitochondria, the researchers ...those substrates into usable forms, the sensing of cellular
energy charge, and the use of that energy for contraction, the researchers explained. In their stu...
Molecule that destroys bone also protects it, new research shows
...mmune diseases. Therapies that target IL-17 or its cellular
receptor currently are being developed. However, a UB molecular biologist has discovered that, in contrast to its action in rheumatoid arthritis(RA), IL-17 actually protects bone in the oral cavity from infectious pathogens such as Porphyromonas gin...
Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness
...d into the cell and are "turned off." In animal, cellular
and biochemical experiments, the researchers found that a lack of nitric oxide leads to a decrease in beta adrenergic receptor number and function. Also, the researchers found that when SNO compounds were administered to mice they could prevent the r...
Story ideas from the Journal of Lipid Research
...holesterol builds up in these cells, especially in cellular
organelles called lysosomes that are known for degrading cholesterol. W. Gray Jerome and colleagues noticed that when cholesterol accumulates in lysosomes, they become less acidic, which makes them less active. The lysosomes become unable to degrad...
$4.4 million NIH grant renews Echinacea and St John's wort research at Iowa State
...rowth conditions of the plant material used in our cellular
and animal model studies," Birt said. "Being able to characterize known-source germplasm is a very important resource for our center." In the renewal, researchers will continue to conduct the anti-viral, anti inflammatory and pain receptor studies ...
Vitamin extends life in yeast, Dartmouth Medical School researchers find
... vitamin, niacin, NR is a precursor to a versatile cellular
factor that is vital for all life. The factor, called NAD, short for nicotinamide adenine dinucleotide, is elevated by calorie restriction. So the researchers set out to develop an intervention to elevate NAD, using yeast cells, whose genes are e...
Keeping the immune system from starting a 'food fight'
...suggest that, over time, the accumulation of small cellular
stresses due to daily changes and fluctuations in nutrients in STAMP2-deficient mice may lead to the activation of inflammatory pathways and inhibition of insulin action, resulting in systemic metabolic deterioration over the long term," he continued...
Study led by Scripps Research scientist reveals little-known cell networks vital to circadian rhythm
...chanisms are in fact essential to the operation of cellular
circadian clocks. "Our study reveals some previously overlooked mechanisms for sustaining cellular
circadian rhythm," said Steve A. Kay, whose laboratory spearheaded the research. "Essentially, when ...
Essential genes cluster clue to order in the genome
...M and an expert in mouse genomics. Chromosomes are cellular
structures that contain genes. Humans have 23 pairs. One of each pair comes from the mother; the other from the father. This is the first time anyone has been able to look at the issue of essential genes in the mouse, said Justice. Essential genes ...
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