Researchers discover gene essencial to cerebellum formation
...t step toward understanding rare diseases, such as cerebellar ataxias, which is characterized by the degeneration of Purkinje cells. Producing this type of cell in the lab may lead to future neuronal replacement therapy....Chemical cues turn embryonic stem cells into cerebellar neurons
... layer on the surface of the cerebellum called the cerebellar cortex. Once in the brain, the cells extended parallel fibers, migrated to and incorporated themselves into the internal granule cell layer, and extended short projections called dendrites, something that neurons use to communicate with each other. E...News tips from the Journal of Neuroscience
...s coexist with conventional L-type channels in rat cerebellar granule cells as well as other neurons. The authors found by quantitative reverse transcription-PCR that the bulk of L-type calcium channel transcripts in granule cells encoded Ca v 1.2 subunits, whereas the remainder encoded Ca v 1.3. Single-channel...News tips from the Journal of Neuroscience
... Husser Purkinje cells provide the sole output of cerebellar cortex, thus serving as the final common pathway for cerebellar synaptic integration and plasticity. The cellular plasticity associated with cerebellar motor learni...Agonized death throes probable cause of open-mouthed, head-back pose of many dino fossils
... to the brain's cerebellum. In humans and animals, cerebellar damage can result from suffocation, meningitis, te...ebraska in the early 20th century. They argue that cerebellar dysfunction explains the opisthotonic posture of the numerous camel-like fossils better than does th...News tips from the Journal of Neuroscience
...rger focused on Purkinje cell (PC) activity in the cerebellar flocculus, an intermediate processing station in smooth-pursuit eye movements. During 200 presentations of the same moving visual stimulus, monkeys showed trial-to-trial variations in behavioral eye movements and in PC firing. This variability was lo......ular system. This region is known as the posterior cerebellar vermis, a narrow, worm-like structure between the brains hemispheres. In their experiments, the researchers measured the electrical activity of these Purkinje cells in monkeys as the animals heads were maneuvered through a precise series of rotatio...