Features of replication suggest viruses have common themes, vulnerabilities
...cell to make new genetic material and maintain the chain of infection. In the case of flock house virus, the Wisconsin group found, the virus co-opts intracellular membranes of mitochondria, critical energy-regulating structures found in most eukaryotic cells. Squeezing into the space between the inn...Circadian clock controls plant growth hormone
... auxin signaling pathway, nearly every step in the chain of events from the production of auxin through to the final growth response showed some regulation by the clock. Covington and Harmer made plants that would glow when the auxin signaling was active. They found a natural rhythm of activity, peaking ...A study by the MUHC and McGill University opens a new door to understanding cancer
...s a basis for us to find ways to intervene in this chain reaction and discover a treatment adds Dr. Gehring. This new information about ubiquitin marks an important advance in our understanding of the mechanisms associated with cancer and contributes to the fight against the disease by directing us towards...New study suggests Concord grape juice may provide protection against breast cancer
...inogen, benzo(a)pyrene, that is able to initiate a chain of events leading to breast cancer. However, the introduction of Concord grape juice compounds blocked the connection of the carcinogen to the DNA of the healthy cells. The purple grape compounds demonstrated the capacity to inhibit DNA adduct fo...Unlocking proteins from their cellular shell
...rocesses from the division of cells to the complex chain of events that result in the apparently simple blink of an eye. Pathophysiological processes such as heart disease, anemia, and even the rigidification of breast tumors often reflect changes in protein organization and assembly that adversely affect...A low expression of MX2 gene exists in the white blood cells of narcoleptics
...les was carried out by semiquantitative polymerase chain reaction (PCR) a biochemistry and molecular biology technique for isolating and exponentially amplifying a fragment or sequence of interest of DNA, via enzymatic replication, without using a living organism using gene-specific primers. Finally,...A new brake on cellular energy production discovered
...cule ATP. As important parts of the respiratory chain are encoded by mitochrondrial DNA, mtDNA, the cell can adapt its energy production to varying needs by increasing or reducing the expression of mtDNA. However, very little is known about how this process is regulated. Two research teams at Karolin...Surprising new species of light-harvesting bacterium discovered in Yellowstone
...orensics and other fields by making the polymerase chain reaction (PCR) a routine procedure. Remarkably, the new genus and species Cab. thermophilum also belongs to a new phylum, Acidobacteria. The discovery marks only the third time in the past 100 years that a new bacterial phylum has been added to ...Innovative research technique reveals another natural wonder in Yellowstone Park
...orensics and other fields by making the polymerase chain reaction (PCR) a routine procedure. ...Hepatitis C helicase unwinds DNA in a spring-loaded, 3-step process
... helicase. Its job is to unwind the tightly coiled chain of nucleic acids the DNA or RNA molecule that spells out the organisms genetic code so that another enzyme, a polymerase, can faithfully copy each nucleotide in the code. Researchers at the University of Illinois, Yale University and the Howard H...Presence of wolves allows aspen recovery in Yellowstone
...eaver dams declined. Food webs broke down, and the chain of effects rippled through birds, insects, fish and other plant and animal species. Aspen, a beautiful hardwood tree with golden fall color, a key to ecosystem biodiversity and a hallmark feature of mountain areas across the West, has been the focu...Camera-shy deer caught for first time
...nnamite Mountains. This densely forested mountain chain straddles the Laos-Vietnam border and is considered one the world's biodiversity hotspots. The cameras were set by staff of the WMPA, a new institution established by the Lao government to manage the more than 1,500 s quare miles of (4,000 square ki...Eat fish -- especially if you drink high levels of alcohol
...he binge-drinking men have decreases in the longer chain n-3 fatty acids, the ones that we typically get from eating fish, and so this suggests that they eat less fish." "Previous studies by Dr. Salem and colleagues have shown that requirements for these nutrients actually increase with greater alcohol c...Species detectives track unseen evolution
...e. Researchers using techniques such as polymerase chain reaction (PCR) and DNA sequencing have increasingly discovered - often unexpectedly - that similar-looking animals within a presumed species are in fact genetically divergent. As well as highlighting hidden biodiversity among creatures zoologists hav...Immune system 'escape hatch' gives cancer cells traction
...y, is that their experiments also suggest that the chain reactions in T-cell tolerance are reversible, raising the possibility of vaccine and drug therapies that break through the blocked immune system. Previous research had confirmed that MDSCs, produced in the bone marrow, were attracted to tumors, ...Crystal structure enables tailoring of pharmaceuticals against asthma
...he cell membranes. Facts: Proteins consist of a chain of amino acids. The length of this chain can range from a few to thousands of amino acids. The chain is then folded in a characteristic way a...Adding folic acid to flour significantly reduces congenital malformations
...it is better to integrate folic acid into the food chain than to focus exclusively on taking vitamin supplements, stated Dr. De Wals. Health Canada still recommends taking folic acid supplements to women in their child-bearing years. Researchers Dr. Philippe De Wals and Fassiatou Tairou of Universit Lava...Elevated CO2 in atmosphere weakens defenses of soybeans to herbivores
...out the ecosystem, including the insect-plant food chain link. Safeguarding highly-usable crops is of great importance to many local and national economies. Many plants have inherent enzyme-based defenses that are released during insect attack. This study found that when soybeans (Glycine max) were expo...Stem cell procedure successfully treats amyloidosis patients
... can help treat patients with immunoglobulin-light chain (AL) Amyloidosis who did not respond to initial treatment with this method. These findings were published on-line in the June 25th issue of Bone Marrow Transplantation. AL amyloidosis occurs when clonal plasma cells in bone marrow produce proteins ......creatic islets have been shown to target insulin B chain amino acids 923 (insulin B:923), and NOD mice lacking insulin B:923 are protected from diabetes. This suggests that insulin, specifically the insulin B:923 sequence, may be essential for the initiation of spontaneous diabetes in NOD mice. In the Ju...